IκB/IKK - MAGL - Proteasome - TBK1 - 15-lipoxygenases
IKK (IκB kinase) is an enzyme complex that participates in NF-κB signaling pathway. It phosphorylates and inhibits IκB, thus leads to the activation of NF-κB. It is a target for treatment of inflammatory diseases and cancer.
- A3635 MRT67307 HClTarget: TBK1|MARK1|NUAK1Summary: SIK/TBK-1/IKKe inhibitor
- A2604 CelastrolTarget: ProteasomeSummary: Antioxidant, anti-inflammatory and immunosuppressive agent
- N1846 Tanshinone IIATarget: AP-1|MAGLSummary: Antioxidant and anti-inflammatory reagent
- N1831 LuteolinTarget: AP-1|MMP|15-lipoxygenasesSummary: Antioxidant and free radical scavenger