Search results for: 'signaling pathways membrane transporter ion channel cftr AND select 5033'
- EntacaponeCatalog No. :A4168COMT inhibitorEntacapone is a second-generation catechol-O-methyltransferase (COMT) inhibitor that potently inhibits rat liver total COMT with the half maximal inhibition concentration IC50 and inhibition constant Ki values of 20.1 nM and 10.7 nM respectively. The IC50 values of entacapone against rate liver soluble COMT (S-COMT) and rat liver membrane-bound COMT (MB-COMT) are 14.3 nM and 73.3 nM respectively .
- T 705Catalog No. :B1114Potent and selective RNA-dependent RNA polymerase inhibitorT 705(Favipiravir) is a RNA-directed RNA polymerase NS5B inhibitor.
- Foscarnet SodiumCatalog No. :B1946Reverse transcriptase inhibitorFoscarnet Sodium inhibits viral RNA polymerases, reverse transcriptase, and DNA polymerases through noncompetitive inhibition with dNTPs.
- TolcaponeCatalog No. :A4383COMT inhibitor
Tolcapone is a novel, reversible and orally-bioavailable small-molecule catechol-O-methyltransferase (COMT) inhibitor used for as an adjunct to levodopa therapy for the treatment of Parkinson’s disease (PD).