Search results for: 'signaling pathways membrane transporter ion channel cftr AND select 5033'
- CP-673451Catalog No. :B2173PDGFRα/β inhibitor,potent and selectiveCP-673451 is a potent inhibitor of PDGFR with IC50 value of 10nM and 1nM for PDGFR-α and PDGFR-β, respectively .
- RegorafenibCatalog No. :A8236Inhibitor of VEGFR/PDGFR/FGFR/mutant kit/RET/Raf-1
Regorafenib (BAY 73-4506) is a novel and orally active multikinase inhibitor of receptor tyrosine kinases VEGFR1, VEGFR2, VEGFR3, PDGFRβ, Kit, RET, Raf-1, B-RAF and B-RAFV600E with IC50 values of 13 nM/4.2 nM/46 nM, 22 nM, 7 nM, 1.5 nM, 2.5 nM, 28 nM and 19 nM .
- PP121Catalog No. :B2172Dual inhibitor of tyrosine and phosphoinositide kinasesPP121 is a dual inhibitor of tyrosine and phosphoinositide kinases .