Search results for: 'signaling pathways membrane transporter ion channel cftr AND select 5033'
- ABT-199Catalog No. :A8194Bcl-2 inhibitor,potent and selective
ABT-199 (GDC-0199) is a Bcl-2-selective inhibitor with Ki of 4800-fold more selective versus Bcl-xL and Bcl-w, and no activity to Mcl-1.
- Romidepsin (FK228, depsipeptide)Catalog No. :A8173HDAC1/HDAC2 inhibitor,potent and selective
Romidepsin, also known as FK228 or depsipeptide, is potent and selective inhibitor of histone deacetylases (HDACs) which are associated with the regulation of re-expression of silenced tumor suppressor genes.
- GS-9973Catalog No. :B3553Syk inhibitor, orally bioavailable and selectiveGS-9973 is an orally bioavailable, selective Syk inhibitor with IC50 of 7.7 nM. Phase 2.
- BRL 50481Catalog No. :B6988PDE7 inhibitor,potent and selectiveSelective PDE7 inhibitor
- SNS-032 (BMS-387032)Catalog No. :A1980CDK inhibitor
Potent inhibitor of cyclin-dependent kinases (cdks) 9, 2 and 7 (IC50 values are 4, 38 and 62 nM respectively).