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  • Search results for: 'all-target'

Search results for: 'all-target'

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Items 1-10 of 15

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  1. PP121
    B2172 PP121
    Target: mTOR|Eph Receptors|VEGFR|PDGFR|Bcr-Abl|Src|DNA-PK|P110|Hck
    Summary: Dual inhibitor of tyrosine and phosphoinositide kinases
      ≥15.95 mg/mL
  2. PTC-209
    B3179 PTC-209
    Target: BMI-1
    Summary: Bmi-1 inhibitor,cell-permeable and small-molecule
      ≥24.75 mg/mL
  3. PD173955
    A8812 PD173955
    Target: Bcr-Abl|Src
    Summary: Dual Src/Abl kinase inhibitor, ATP-competitive,
      ≥22.15 mg/mL
  4. Butein
    A2689 Butein
    Target: Src|STAT|EGFR|Angiotensin-Converting Enzymes (ACEs)|5-Lipoxygenases|PTK|enoyl-acyl-carrier protein reductase
    Summary: Protein kinase inhibitor
      ≥13.6 mg/mL
  5. Ponatinib (AP24534)
    A5467 Ponatinib (AP24534)
     1 Citation
    Target: VEGFR|PDGFR|Bcr-Abl|FGFR|Src
    Summary: pan-BCR-ABL inhibitor,multi-kinase inhibitor
      ≥53.3 mg/mL
      <2.45 mg/mL
      <2.31 mg/mL
  6. Saracatinib (AZD0530)
    A2133 Saracatinib (AZD0530)
     3 Citation
    Target: Src
    Summary: Src/Abl inhibitor,potent and selective
      ≥27.1 mg/mL
  7. CP-724714
    A2412 CP-724714
    Target: VEGFR|PDGFR|Bcr-Abl|Src|EGFR|c-MET|Insulin Receptors|IRG-1R
    Summary: HER2 inhibitor,potent and selective
      ≥23.5 mg/mL
  8. Bosutinib (SKI-606)
    A2149 Bosutinib (SKI-606)
     1 Citation
    Target: Bcr-Abl|Src
    Summary: Potent Abl/Src kinases
      ≥26.5 mg/mL
  9. PP 1
    A8215 PP 1
    Target: Src|EGFR|JAK|ZAP-70
    Summary: Src family tyrosine kinase inhibitor
      ≥7.03 mg/mL
      ≥20.6 mg/mL
      <2.74 mg/mL
  10. TG 100801
    A3870 TG 100801
    Target: VEGFR|FGFR|Src|Fyn kinase
    Summary: Multi-kinase inhibitor
      soluble in dmso

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Category
Specificity
  1. Selective 8 items
Reversibility
  1. Reversible 1 item
Target
  1. Caspases 9 items
  2. Cyclin-Dependent Kinases 19 items
  3. Adenosine A2A Receptors 3 items
  4. Proteasome 6 items
  5. Cathepsins 10 items
  6. Histone Deacetylases (HDACs) 26 items
  7. Inhibitor of apoptosis proteins (IAP) 2 items
  8. Akt 10 items
  9. Bcl-2 7 items
  10. PI3K 23 items
  11. CXCR 2 items
  12. Raf 11 items
  13. Aurora Kinases 19 items
  14. Bcl-xl 3 items
  15. CSF-1R 2 items
  16. Glycoproteins 2 items
  17. Gap Junctions 3 items
  18. MDM2 2 items
  19. EZH2 4 items
  20. mTOR 16 items
  21. Bromodomains 8 items
  22. MMP 5 items
  23. Thymidine Phosphorylases 1 item
  24. Androgen Receptors 3 items
  25. Peptidylprolyl isomerases 1 item
  26. Acyl coenzyme A: cholesterol acyltransferases 1 item
  27. DT-diaphorases 1 item
  28. FLT3 13 items
  29. GSK-3 9 items
  30. Factor Xa 2 items
  31. Farnesoid X receptors (FXRs) 1 item
  32. LPA Receptors 3 items
  33. P-glycoprotein (P-gp) 4 items
  34. PLK 7 items
  35. Chk 4 items
  36. Eph Receptors 2 items
  37. VEGFR 30 items
  38. PDGFR 20 items
  39. c-Kit 8 items
  40. RET 4 items
  41. IRAK 3 items
  42. Bromodomain-containing proteins(BRDs) 1 item
  43. Phosphodiesterases (PDEs) 3 items
  44. Mcl-1 4 items
  45. Hydrolase 1 item
  46. Thymidylate Synthase 1 item
  47. p38 5 items
  48. PKB 1 item
  49. JNK 2 items
  50. SGK 1 item
  51. Bcr-Abl 11 items
  52. MEK 16 items
  53. PORCN 1 item
  54. DOT1L 2 items
  55. FGFR 12 items
  56. Nrf2 1 item
  57. Insulin-like growth factor receptors(IGFRs) 1 item
  58. CGRP receptors 2 items
  59. Pim 2 items
  60. Liver X receptors (LXRs) 2 items
  61. Sir2-like Family Deacetylases (Sirtuins) 3 items
  62. Voltage-gated Sodium (NaV) Channels 1 item
  63. Deubiquitinating enzymes (DUBs) 2 items
  64. Smoothened 3 items
  65. Ribosomal s6 kinases (RSK) 1 item
  66. MET 6 items
  67. Src 13 items
  68. RARs 1 item
  69. Trk Receptors 2 items
  70. Integrins 1 item
  71. Aminopeptidases 2 items
  72. NMDA Receptors 2 items
  73. STAT 5 items
  74. Microtubules/Tubulins 4 items
  75. EGFR 21 items
  76. Hedgehog 1 item
  77. Reverse Transcriptases 1 item
  78. ROCK 4 items
  79. BTK 1 item
  80. RIP kinases 1 item
  81. PAK 3 items
  82. sulfhydryls (-SH) 1 item
  83. FAK 6 items
  84. BMP and Other Activin Receptors 3 items
  85. JAK 16 items
  86. p300 1 item
  87. Stearoyl-CoA 9-desaturase (SCD-1) 1 item
  88. Syk 4 items
  89. EZH1 1 item
  90. DNA-PK 5 items
  91. HSP90 9 items
  92. Gutathione S-transferase 1 item
  93. CCR 2 items
  94. PDHK 1 item
  95. Angiotensin AT2 Receptors 1 item
  96. eIF4E/eIF3G interaction 1 item
  97. CFTR 3 items
  98. TNKS 1 item
  99. Topoisomerases 5 items
  100. Cytochrome P450 (CYP450) 3 items
  101. Ribosomes 1 item
  102. ErbB 4 items
  103. Ferroptosis 1 item
  104. Toll-like receptors (TLRs) 1 item
  105. Adenosine Kinases 1 item
  106. Serine Proteases 1 item
  107. DNA Methyltransferases 3 items
  108. Survivin 1 item
  109. Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitors (HIF-PHIs) 1 item
  110. ERK 4 items
  111. HMG-CoA Reductases 1 item
  112. c-MET 7 items
  113. BMI-1 1 item
  114. PKC 9 items
  115. Calpains 4 items
  116. Ubiquitin-specific proteases 1 item
  117. HCV Proteases 2 items
  118. Ca2 /calmodulin-dependent protein kinases (CaMKs) 3 items
  119. CREBBP 2 items
  120. EP300 2 items
  121. Protease-Activated Receptors 2 items
  122. Lyn 1 item
  123. SGLT 1 item
  124. RAD51 1 item
  125. Trypsins 1 item
  126. HER2 2 items
  127. Pyk2 3 items
  128. LRRK2 3 items
  129. S1P receptors 2 items
  130. Calcium chelator 1 item
  131. DGAT 1 item
  132. Insulin and Insulin-like Receptors 5 items
  133. PARP 8 items
  134. CB1 Receptors 1 item
  135. Pyruvate dehydrogenases (PDH) 1 item
  136. ALK 7 items
  137. Sphingosine kinases (SphKs) 1 item
  138. Trypsin 1 item
  139. Chymotrypsin 1 item
  140. Kallikrein 1 item
  141. Trypsinogen 1 item
  142. KRAS G12C 1 item
  143. GTPases 1 item
  144. CETP 2 items
  145. Dehydrogenase 1 item
  146. PKG 1 item
  147. PKA 5 items
  148. HIV-1 gp120 1 item
  149. 5-HT1 Receptors 1 item
  150. 5-HT7 Receptors 1 item
  151. Valosin-containing protein (VCP) 1 item
  152. MELK 1 item
  153. Insulin-like growth factors (IGFs) 1 item
  154. Clk 1 item
  155. TBK1 1 item
  156. MARK1 1 item
  157. NUAK1 1 item
  158. Integrin-ligand interactions 1 item
  159. Bromodomain and Extra-Terminal motif (BET) 1 item
  160. MK2 1 item
  161. 5-HT3 Receptors 1 item
  162. Angiotensin-Converting Enzymes (ACEs) 1 item
  163. Tie-2 2 items
  164. RSK 1 item
  165. Free Fatty Acid Receptors 1 item
  166. phosphatases 2 items
  167. Autophagy 1 item
  168. ATM/ATR 6 items
  169. COX 1 item
  170. YAP 1 item
  171. IDH2 1 item
  172. HIV Integrases 2 items
  173. Melatonin Receptors 1 item
  174. Nampt 1 item
  175. eIF4F 1 item
  176. Cdc42 1 item
  177. SRPK1 1 item
  178. P2X Receptors 2 items
  179. Ron 1 item
  180. G9a 1 item
  181. Histamine H1 Receptors 1 item
  182. RAR/RXR 1 item
  183. P110 1 item
  184. Hck 2 items
  185. GABAA Receptors 1 item
  186. Phospholipases 1 item
  187. TRP Channel 1 item
  188. Histone Demethylases 1 item
  189. MNK 1 item
  190. 5-Lipoxygenases 1 item
  191. Calcium-Activated Potassium (KCa) Channels 2 items
  192. AChE 2 items
  193. Insulin Receptors 1 item
  194. IRG-1R 1 item
  195. eEF-2 1 item
  196. Cdc7 1 item
  197. ZAP-70 1 item
  198. Angiotensin AT1 Receptors 1 item
  199. O6-methylguanine-DNA-methyl-transferase (MGMT) 1 item
  200. Antioxidants 2 items
  201. Papains 1 item
  202. Na /Ca2 Exchangers (NCXs) 1 item
  203. Ubiquitin-activating Enzyme E1 1 item
  204. BACE 3 items
  205. Cytidine deaminases 1 item
  206. GPR40 1 item
  207. angiogenesis 1 item
  208. Glucagon Receptors 1 item
  209. DPP-4 2 items
  210. c-RET 1 item
  211. Nonstructural protein 5B (NS5B) 1 item
  212. guanylyl cyclase 1 item
  213. p70 rsk 2 items
  214. FPTase 1 item
  215. Microtubule/Tubulin 1 item
  216. Myosin 1 item
  217. VEGFR3/FLT4 1 item
  218. NTRK1/TRKA 1 item
  219. CSF-1R/c-Fms 1 item
  220. Tryptophan hydroxylases (TPH) 1 item
  221. Bfl-1 1 item
  222. p53-MDM2 interaction 2 items
  223. KDR 2 items
  224. Fyn kinase 1 item
  225. Glyoxalase I 1 item
  226. p53 6 items
  227. HDAC 1 item
  228. Antifungal 1 item
  229. c-Fms tyrosine kinase 1 item
  230. insulin 1 item
  231. Ub-conjugating enzyme (E2) complex 1 item
  232. Smoothened receptor 1 item
  233. cysteine protease 2 items
  234. PPAR 3 items
  235. HDM2 ubiquitin ligase 1 item
  236. IKK 1 item
  237. GABA receptors 1 item
  238. gp120-CD4 interaction 1 item
  239. HCV polymerase 3 items
  240. Ftase 1 item
  241. PC-PLC 1 item
  242. GK 1 item
  243. P97 ATPase 1 item
  244. Glucosidases 1 item
  245. Vitamin D receptors (VDRs) 1 item
  246. Mer tyrosine kinase 1 item
  247. neprilysin 1 item
  248. GLI 1 item
  249. ErbB-2 1 item
  250. TRPA 1 item
  251. sterol demethylase 1 item
  252. PDK-1 1 item
  253. telomerase 1 item
  254. Prk 1 item
  255. Ribonucleotide Reductases 1 item
  256. HSP70 1 item
  257. Pregnane X receptor(PXR) 1 item
  258. ITK 2 items
  259. folate receptor 1 item
  260. NUAK 1 item
  261. DCLK2 1 item
  262. FAAH 1 item
  263. PTK 1 item
  264. L3MBTL 1 item
  265. MDMX 1 item
  266. TYK2 1 item
  267. MUSK 1 item
  268. MAP3K 1 item
  269. Lck 2 items
  270. SERT 1 item
  271. DprE 1 item
  272. Vitamin D 1 item
  273. Flk1 2 items
  274. p21 1 item
  275. DHFR 1 item
  276. GARFT 1 item
  277. FGR 1 item
  278. YES 1 item
  279. Fyn 1 item
  280. ARG 1 item
  281. Autotaxin 1 item
  282. UCH 1 item
  283. RHA 1 item
  284. TRPC channel 1 item
  285. enoyl-acyl-carrier protein reductase 1 item
  286. FKBP 1 item
  287. Bcl-w 1 item
  288. topoisomerase 1 item
  289. PPK 1 item
  290. c-Syk 1 item
  291. CDK1/CyclinB 1 item
  292. IDO 1 item
  293. FXR 1 item
  294. reverse transcriptase 1 item
  295. Vascular Disrupting Agents (VDA) 1 item
  296. Androgen Receptor 1 item
  297. gp120/CD4 1 item
  298. ATM 2 items
  299. Sirtuin 1 item
  300. NE 1 item
  301. PIKfyve 1 item
  302. Glycogen Phosphorylases 1 item
  303. MTH1 1 item
  304. Insulin Receptor 1 item
  305. NS3/4a Proteases 1 item
  306. p90 S6K 1 item
Reported Experiments
  1. Animal Experiments 13 items
  2. Cell Experiments 11 items
Related Disease
  1. Breast Cancer 1 item
  2. Cancer 8 items
  3. Colorectal Cancer 1 item
  4. Glioblastoma 1 item
  5. Lung Cancer 1 item
  6. Prostate Cancer 1 item
  7. Renal Cancer 1 item