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Metabolism

  1. Cat.No. Product Name Information
  2. B4750 (-)-p-Bromotetramisole Oxalate ALP inhibitor, potent and non-specific
  3. A8703 Isosafrole A stiripentol analog, a potent LDH inhibitor.
  4. A8704 Stiripentol An LDH inhibitor
  5. A3152 Aleglitazar PPARα/PPARγagonist
  6. A3216 Balaglitazone PPAR-γ partial agonist
  7. A3453 GW1929 Potent PPARγ agonist
  8. A3498 Inolitazone PPARgamma agonist
  9. A3893 Troglitazone Selective PPARγ agonist
  10. A4300 GW9662 PPARγ antagonist
  11. A4324 Pioglitazone HCl PPARγ agonist
  12. A4310 Rosiglitazone HCl PPARγ agonist
  13. A4301 T0070907 Human PPARγ antagonist,potent and selective
  14. A4302 Rosiglitazone maleate PPARγ agonist,high-affinity and selective,potent insulin sensitizer
  15. A4303 GSK3787 PPARβ/δ antagonist,novel and irreversible
  16. A4304 Rosiglitazone Potent PPARγ agonist
  17. A4305 WY-14643 (Pirinixic Acid) PPARα agonist,selective and highly potent
  18. A4306 Ciprofibrate PPARα agonist
  19. A4307 GW0742 PPARδ/β agonist,potent and selective
  20. A4309 GW501516 PPARδ agonist,selective and potent
  21. C5151 Cetaben unique,PPARα-independent peroxisome proliferator
  22. C4892 MCC-555 thiazolidinedione class anti-diabetic compound,a novel PPARα/γ dual ligand
  23. C4735 N-Octadecyl-N'-propyl-sulfamide activator of PPARα
  24. C4916 GW 590735 potent and selective agonist of PPARα
  25. C4758 Darglitazone PPARγ agonist with antidiabetic actions
  26. C5263 LT175 dual PPARα/γ ligand
  27. C5280 3-Thiatetradecanoic Acid activator of PPAR
  28. C5631 Glycerophospho-N-Oleoyl Ethanolamine precursor of oleoyl ethanolamide (OEA)
  29. C5712 DG-172 (hydrochloride) orally available inverse agonist of PPARβ/δ
  30. C5557 SR 1824 non-agonist PPARγ ligand
  31. C5435 G3335 PPARγ antagonist
  32. C5572 SR 2595 inverse agonist of PPARγ
  33. C5671 RB394 dual modulator of soluble epoxide hydrolase (sEH) and PPARγ
  34. C3986 Muraglitazar dual agonist of PPARα and PPARγ
  35. C3544 BMS 687453 PPARα agonist
  36. A3536 L-165041 PPARβ/δ agonist,cell permeable,potent and selective
  37. A3499 Inolitazone dihydrochloride PPARγ agonist,high-affinity and novel
  38. B6681 Ciglitazone PPARγ agonist
  39. B6691 BADGE PPARγ antagonist
  40. B6826 GW 7647 PPARα agonist
  41. B6929 SR 202 PPAR antagonist
  42. B6955 nTZDpa PPARγ partial agonist
  43. B7406 GSK 0660 PPARδ antagonist
  44. B7471 S26948 PPARγ agonist
  45. B7553 Tesaglitazar Dual-specificity PPARα/γ agonist
  46. B7609 CP 775146 PPARα agonist
  47. B5581 SR 1664 inhibits Cdk5-mediated PPARγ phosphorylation, antidiabetic agent
  48. A8957 AUDA Potent epoxide hydrolase inhibitor/PPARα activator
  49. B6128 Fenofibric acid ppar inhibitor, lipid-lowering agent
  50. C3407 GQ-16 partial agonist for PPARγ
  51. B7010 15-deoxy-Δ-12,14-Prostaglandin J2 PPARγ agonist
  52. B2117 Pioglitazone PPAR agonist
  53. B1943 Fenofibrate PPARα agonist
  54. B1947 Gemfibrozil PPARα activator
  55. B3610 Clofibrate PPAR agonist
  56. A5143 Finasteride Inhibitor of Type II 5α-reductase
  57. A1659 Dutasteride 5-alpha-reductase inhibitor
  58. B1195 Finasteride acetate 5α-reductase inhibitor
  59. B3422 U-73122 inhibitor of phospholipase C, phospholipase A2, and 5-LO (5-lipoxygenase)
  60. B1207 Zileuton sodium 5-lipoxygenase and leukotrienes inhibitor
  61. A5384 Zileuton 5-lipoxygenase (5-LOX) inhibitor, orally active
  62. A2486 Malotilate Stimulates hepatocyte regeneration
  63. C4828 Piriprost (potassium salt) 5-lipoxygenase inhibitor
  64. C4371 BW 755C dual inhibitor of 5-lipoxygenase (5-LO) and cyclooxygenase (COX) pathways
  65. C4199 HZ52 5-lipoxygenase inhibitor
  66. C3091 11-keto-β-Boswellic Acid leukotriene synthesis inhibitor via 5-lipoxygenase
  67. C4696 Ebselen
  68. C3055 3-acetyl-11-keto-β-Boswellic Acid 5-lipoxygenase inhibitor
  69. C3794 1-Naphthyl 3,5-dinitrobenzoate dual 5-lipoxygenase and microsomal prostaglandin E synthase-1 inhibitor
  70. A3277 Capadenoson Adenosine A1 receptor agonist
  71. B6662 EHNA hydrochloride cGMP-stimulated phosphodiesterase (PDE2) and adenosine deaminase inhibitor
  72. B5619 1-Deazaadenosine adenosine deaminase inhibitor
  73. A4355 Tosedostat (CHR2797) Aminopeptidase inhibitor
  74. A1718 Posaconazole Sterol C14ɑ demethylase inhibitor
  75. B1225 Posaconazole hydrate C14ɑ demethylase inhibitor
  76. A4364 Methazolamide Carbonic anhydrase inhibitor
  77. A4360 Topiramate GluR5 receptor antagonist,anticonvulsant
  78. A4359 Brinzolamide CA II inhibitor
  79. A4357 Dorzolamide HCl Carbonic anhydrase inhibitor
  80. A4358 U-104 CAIX inhibitor
  81. A4362 Tioxolone CAI inhibitor
  82. B6125 Acetazolamide carbonic anhydrase (CA) inhibitor
  83. B6154 Benzenesulfonamide carbonic anhydrase inhibitor
  84. A4378 Torcetrapib CETP inhibitor
  85. A4376 Dalcetrapib (JTT-705, RO4607381) rhCETP inhibitor
  86. A4375 Anacetrapib (MK-0859) RhCETP/mutant CETP(C13S) inhibitor
  87. A4377 Evacetrapib (LY2484595) CETP inhibitor,potent and selective
  88. A8430 Ezetimibe Cholesterol transport inhibitor
  89. A3404 Etomoxir (CPT)-1 and DGAT activity inhibitor
  90. C4945 Perhexiline (maleate) CPT1 and CPT2 inhibitor
  91. A4313 Cobicistat (GS-9350) Selective CYP3A inhibitor
  92. C4880 6,7-dihydroxy Bergamottin potent inhibitor of CYP3A4
  93. C4691 4-phenyl-1,2,3-Thiadiazole selective inhibitor of certain CYP450 enzymes (CYP2B4, CYP2E1)
  94. C5228 DDMS CYP4A2 enzyme inhibitor
  95. C5234 PPOH inhibitor of CYP epoxidase activity on arachadonic acid
  96. C5540 4β-hydroxy Cholesterol marker for CYP3A4/5 activity
  97. C5345 Tienilic Acid specific suicide substrate for CYP2C9 and CYP2C10
  98. B5990 Diosmetin CYP1A1 inhibitor
  99. B5963 7-Ethoxyresorufin Specific subtrate of CYP1A
  100. A4322 Clarithromycin CYP3A inhibitor, potent
  101. A3374 Dronedarone CYP3A4 and 2D6 inhibitor,moderate
  102. B7737 ABT Cytochrome P450 inhibitor
  103. B5723 Methoxyresorufin fluorometric substrate of cytochrome P450
  104. B5724 Pentoxyresorufin fluorometric cytochrome P450 substrate
  105. B6768 TMS cytochrome P450 1B1 inhibitor
  106. B7714 3-Cyano-7-ethoxycoumarin Fluorescent P450 substrate
  107. B5405 YM 511 aromatase (CYP19) inhibitor
  108. A4320 Voriconazole CYP51 inhibitor
  109. B4692 Dafadine-A DAF-9 cytochrome P450 inhibitor
  110. B4685 VT-464 racemate CYP17 lyase inhibitor
  111. B4684 VT-464 R enantiomer CYP17 lyase inhibitor
  112. B4683 VT-464 Human CYP17 lyase inhibitor
  113. A4351 PluriSIn #1 (NSC 14613) Top Seller SCD1 inhibitor
  114. A4348 Trilostane 3β-HSD inhibitor
  115. A4342 Gimeracil Dihydropyrimidine dehydrogenase inhibitor
  116. A4339 AGI-5198 Top Seller IDH1 inhibitor against R132 mutant,selective and cell-permeable
  117. A4336 Mycophenolate Mofetil IMPDH inhibitor
  118. B7804 AG-221 (Enasidenib) mutant isocitrate dehydrogenase 2 (IDH2) inhibitor
  119. B7805 AG-120 mutant IDH1 inhibitor
  120. B7824 ML390 human DHODH inhibitor
  121. C3039 STK393606 competitive inhibitor of NAD+-dependent type-I 15-hydroxy PGDH
  122. C3535 Piericidin A mitochondrial complex I inhibitor
  123. C3853 NCT-503 3-phosphoglycerate dehydrogenase (PHGDH) inhibitor
  124. C4497 6-Aminonicotinamide 6-phosphogluconate dehydrogenase inhibitor
  125. C4671 Inosine-5'-monophosphate (sodium salt hydrate) substrate of IMP dehydrogenase (IMPDH)
  126. C4845 PHGDH-inactive inactive analog of the 3-phosphoglycerate dehydrogenase (PHGDH) inhibitors NCT-502 and NCT-503
  127. C5603 A-771726 dihydroorotate dehydrogenase inhibitor
  128. C5478 NCT-502 inhibitor of 3-phosphoglycerate dehydrogenase (PHGDH)
  129. B6124 Fomepizole competitive inhibitor of the enzyme alcohol dehydrogenase
  130. A1606 L-a-Hydroxyglutaric acid disodium salt salt form of L-α-Hydroxyglutaric acid
  131. A3837 DL-α-Hydroxyglutaric acid disodium salt alpha hydroxy acid
  132. A3146 AGI-6780 IDH2/R140Q mutation inhibitor
  133. B4669 Vidofludimus DHODH inhibitor
  134. A4333 CPI-613 PDH/α-KGDH inhibitor
  135. B7725 Methylmalonate reversible succinate dehydrogenase inhibitor
  136. B5697 WIN 18446 inhibitor of aldehyde dehydrogenase 1a2 (ALDH1a2)
  137. B5716 Galloflavin human lactate dehydrogenase (LDH) inhibitor
  138. B5354 CGP 3466B maleate GAPDH inhibitor
  139. B5508 Alda 1 ALDH2 activator
  140. B5643 TC HSD 21 17β-hydroxysteroid dehydrogenase type 3 (17β-HSD3) inhibitor
  141. B5799 Qc 1 threonine dehydrogenase (TDH) inhibitor
  142. B4928 CVT 10216 reversible inhibitor of aldehyde dehydrogenase 2 (ALDH2)
  143. B4929 GSK 2837808A Potent, selective lactate dehydrogenase A (LDHA) inhibitor
  144. B6104 BVT 2733 11beta-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor
  145. A8721 CBR-5884 selective inhibitor of PHGDH
  146. B1129 Mutant IDH1 inhibitor Potent mutant IDH1 R132H inhibitor
  147. A4347 Methotrexate Folate antagonist,inhibits DFHR
  148. A4350 Pralatrexate Antifolate,a folate analog
  149. A4353 Pyrimethamine DHFR inhibitor
  150. A4390 Pemetrexed Top Seller TS, DHFR,GARFT and AICARFT inhibitor
  151. A3707 Pemetrexed disodium hemipenta hydrate Antifolate and antimetabolite agent
  152. C5763 Cycloguanil (hydrochloride) inhibitor of dihydrofolate reductase (DHFR)
  153. A3363 DGAT-1 inhibitor Diacylglycerol acyltransferase (DGAT1) inhibitor
  154. A3215 AZD7687 DGAT inhibitor,potent and selective
  155. A3542 LCQ-908 DGAT1 inhibitor
  156. A3140 ABT-046 DGAT-1 inhibitor,potent and selective
  157. A3364 DGAT-1 inhibitor 2 Antiobesity agents
  158. C4875 Amidepsine D DGAT inhibitor
  159. C4872 Amidepsine A DGAT inhibitor
  160. B4822 DGAT1-IN-1 potent DGAT1 inhibitor
  161. B4944 AZD 3988 diacylglycerol acyltransferase (DGAT-1) inhibitor
  162. A4015 Disulfiram Dopamine β-hydroxylase inhibitor
  163. A4330 Isotretinoin Dopamine β-hydroxylase activator
  164. A4332 Nepicastat (SYN-117) HCl Dopamine-β-hydroxylase inhibitor
  165. A4335 Mildronate GBB hydroxylase inhibitor
  166. C5062 Fusaric Acid inhibitor of dopamine β-hydroxylase
  167. B7346 PF 915275 11β-hydroxysteroid dehydrogenase type 1 (11βHSD1) inhibitor
  168. B3588 AP-III-a4 enolase inhibitor
  169. A3714 PF-04457845 FAAH inhibitor,potent and exquisitely selective
  170. B5714 SA 47 FAAH inhibitor
  171. B5704 SA 57 FAAH inhibitor
  172. B5562 TC-F 2 FAAH inhibitor
  173. B7701 JZL 195 Dual inhibitor of fatty acid amide hydrolase (FAAH) and monoacylglycerol lipase (MAGL)
  174. B7356 PF 750 FAAH inhibitor
  175. A3571 LY2183240 Blocker of anandamide uptake,highly potent
  176. A4372 URB597 FAAH inhibitor,potent and selective
  177. A4361 JNJ-1661010 FAAH inhibitor,potent and selective
  178. C4756 PF-622 potent, time-dependent, irreversible FAAH inhibitor
  179. C5719 Oleyl Trifluoromethyl Ketone potent inhibitor of FAAH
  180. C5452 Monoacylglycerol Lipase Inhibitor 21 inhibitor of monoacylglycerol lipase (MAGL) and FAAH
  181. C5619 N-Benzylpalmitamide inhibitor of fatty acid amide hydrolase (FAAH)
  182. C5178 Methyl α-Linolenyl Fluorophosphonate inhibitor of phospholipases, FAAH
  183. B4931 TAK 21d Potent FAAH inhibitor
  184. C4251 Oleoyl Ethyl Amide FAAH inhibitor with potential analgesic and anxiolytic activity
  185. C4122 JNJ-42165279 FAAH inhibitor
  186. C4279 4-(n-nonyl) Benzeneboronic Acid FAAH and MAGL inhibitor
  187. C4983 JP83 irreversible fatty acyl amide hydrolase (FAAH) inhibitor
  188. B1245 FAAH inhibitor 1 Potent fatty acid amide hydrolase (FAAH) inhibitor
  189. A4374 PF-3845 FAAH ihibitor,highly potent and selective
  190. A4338 Rivaroxaban Factor Xa inhibitor
  191. B3234 Betrixaban Factor Xa inhibitor
  192. A4344 Ozagrel Thromboxane A2 synthetase inhibitor
  193. A4371 Ferrostatin-1 (Fer-1) Ferroptosis inhibitor, erastin-induced
  194. B4987 Liproxstatin-1 A potent ferroptosis inhibitor
  195. A2489 Leucovorin Calcium Derivative of folic acid
  196. A3552 Levomefolate calcium Artificial form of folate
  197. B1108 Ro 28-1675 Glucokinase activator
  198. B2160 LY2608204 GK activator
  199. A3369 DMP 777 Leukocyte elastase (HLE) inhibitor
  200. B1124 Pitavastatin HMG-CoA reductase inhibitor
  201. A8522 Simvastatin (Zocor) HMGCR (HMG-CoA reductase) inhibitor

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