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In vitro transcription of capped mRNA with modified nucleotides and Poly(A) tail
TSA (Tyramide Signal Amplification), used for signal amplification of ISH, IHC and IC etc.
Separation of phosphorylated and non-phosphorylated proteins without phospho-specific antibody
A convenient and sensitive way for cell proliferation assay and cytotoxicity assay
Protect the integrity of proteins from multiple proteases and phosphatases for different applications.
Animal models
Rats
Dosage form
0.5~10 mg/kg (i.v.)
Application
The results showed that Loteprednol etabonate showed a rapid dose-dependent elimination effect, with a total blood clearance of more than 60 ml/min/kg. Loteprednol etabonate, which is absorbed systemically after topical administration, can be quickly converted into inactive metabolites and is mainly cleared from the body by bile and urine.
Other notes
Please test the solubility of all compounds indoor, and the actual solubility may slightly differ with the theoretical value. This is caused by an experimental system error and it is normal.
References:
[1]. Bodor N, Wu WM, Murakami T, Engel S. Soft drugs. 19. Pharmacokinetics, metabolism and excretion of a novel soft corticosteroid, loteprednol etabonate, in rats. Pharm Res. 1995 Jun;12(6):875-9. PubMed PMID: 7667193.