Untitled Document
  ChemDraw06111414182D

 30 33  0  0  0  0  0  0  0  0999 V2000
   -2.4452   -1.5763    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.2317   -2.3732    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4348   -2.5867    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.8514   -2.0034    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.0650   -1.2065    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.8619   -0.9929    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.0546   -2.2169    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.5288   -1.6335    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.3153   -0.8366    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.4816   -0.6231    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.8986   -0.2533    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.6851    0.5436    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.1118    0.7571    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.6951    0.1738    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.7225   -0.2964    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.0182    0.4738    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.3770    0.9929    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.8151   -2.9566    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4775   -0.4920    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.1961   -0.2106    0.0000 F   0  0  0  0  0  0  0  0  0  0  0  0
    1.0298   -1.2491    0.0000 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.3111   -0.9677    0.0000 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.4716    1.3405    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.9645    1.7074    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.9604    1.5763    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.7469    2.3732    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.7573    1.3628    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.3302    2.9566    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.8151    0.6873    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4920    0.3873    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0      
  2  3  1  0      
  3  4  2  0      
  4  5  1  0      
  5  6  1  0      
  6  1  2  0      
  4  7  1  0      
  7  8  1  0      
  8  9  1  0      
  9 10  1  0      
 10  5  1  0      
  9 11  1  0      
 11 12  1  0      
 12 13  1  0      
 13 14  1  0      
 14 10  1  0      
 11 15  1  0      
 15 16  1  0      
 16 17  1  0      
 17 12  1  0      
  2 18  2  0      
  5 19  1  1      
 10 20  1  6      
  9 21  1  6      
 11 22  1  6      
 12 23  1  1      
 17 24  1  6      
 17 25  1  0      
 25 26  1  0      
 25 27  2  0      
 26 28  1  0      
 16 29  1  6      
 14 30  1  1      
M  END
>  <Catalog Number> (1)
A2324

>  <Item Name> (1)
Dexamethasone (DHAP)

>  <Formula> (1)
C22H29FO5

>  <MolWeight> (1)
392.46

>  <CAS Number> (1)
1950-2-2

>  <Target> (1)
Autophagy

>  <URL> (1)
http://www.apexbt.com/search.php?catalog=A2324

$$$$

Untitled Document
  ChemDraw06111414292D
 24 26  0  0  0  0  0  0  0  0999 V2000
   -2.2265    2.3923    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.7891    1.7889    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.5479    1.0000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.7441    0.8144    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.1814    1.4178    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4226    2.2067    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.3441    0.0928    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
   -0.5342    0.2503    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.4337    1.0691    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
   -2.4677    3.1813    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -3.2715    3.3668    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.0691   -0.3124    0.0000 S   0  0  0  0  0  0  0  0  0  0  0  0
   -0.1165   -1.1162    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.4869   -1.6789    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.8581   -0.0712    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.3013   -2.4828    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
    0.9047   -3.0454    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.6936   -2.8042    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.8792   -2.0003    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.2759   -1.4377    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4614   -0.6338    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.6682   -1.7591    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.2715   -2.3218    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.2970   -3.3668    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0      
  2  3  2  0      
  3  4  1  0      
  4  5  2  0      
  5  6  1  0      
  6  1  2  0      
  4  7  1  0      
  7  8  2  0      
  8  9  1  0      
  9  5  1  0      
  1 10  1  0      
 10 11  1  0      
  8 12  1  0      
 12 13  1  0      
 13 14  1  0      
 12 15  2  0      
 14 16  2  0      
 16 17  1  0      
 17 18  2  0      
 18 19  1  0      
 19 20  2  0      
 20 14  1  0      
 20 21  1  0      
 19 22  1  0      
 22 23  1  0      
 18 24  1  0      
M  END
>  <Catalog Number> (1)
A2845

>  <Item Name> (1)
Omeprazole

>  <Formula> (1)
C17H19N3O3S

>  <MolWeight> (1)
345.42

>  <CAS Number> (1)
73590-58-6

>  <Target> (1)
Autophagy

>  <URL> (1)
http://www.apexbt.com/search.php?catalog=A2845

$$$$

Untitled Document
  ChemDraw03251614422D
 64 71  0  0  0  0  0  0  0  0999 V2000
   -4.8226   -4.8543    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.9991   -4.9043    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.5441   -4.2161    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.8060   -3.8476    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.7561   -3.0241    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.2722   -2.3559    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.3427   -1.5339    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.9333   -0.9579    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.7568   -0.9080    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.4126   -1.4084    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.5820   -2.2158    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.1824   -2.9376    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
   -3.4442   -2.5691    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.2323   -3.7611    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.9637   -0.1093    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.6957    0.2712    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.7321    1.0954    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.0365    1.5390    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.3046    1.1585    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.2682    0.3343    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.6313   -0.1902    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
   -1.2738   -1.6217    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.9211   -2.3675    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.0988   -2.4349    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.3707   -1.7566    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.0180   -1.0108    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.8042   -0.9433    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.6184   -0.4449    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.1945   -0.5858    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.6232    0.1190    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.1242    0.7760    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
    0.5995    0.3799    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.3044    0.8086    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.2855    1.6334    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.5618    2.0295    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.1430    1.6008    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.0281    0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.0469   -0.4122    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.3421   -0.8410    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.1890   -1.6516    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
    1.7549   -2.2520    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.7706   -0.8083    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.7463   -1.6330    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.4970   -0.4171    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.1989   -0.8505    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.7518    0.0165    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.1559    1.0985    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.1370    1.9233    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.4133    2.3193    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.8419    2.3520    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.0092    1.2373    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.9904    2.0621    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.3906   -3.0458    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -2.2129   -2.9783    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.8731   -0.8556    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.0509   -0.9231    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -2.2258   -0.1098    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -1.7563    0.5686    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.1756   -4.9542    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.6220    3.7880    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.2223    4.3539    0.0000 S   0  0  0  0  0  0  0  0  0  0  0  0
    4.7882    3.7536    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.6564    4.9542    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.8226    4.9198    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0      
  2  3  1  0      
  3  4  1  0      
  4  5  1  0      
  5  6  1  0      
  6  7  1  0      
  7  8  1  0      
  8  9  2  0      
  9 10  1  0      
 10 11  1  0      
 11 12  1  0      
 12 13  1  0      
  5 13  1  0      
 12 14  1  0      
  3 14  1  0      
  9 15  1  0      
 15 16  2  0      
 16 17  1  0      
 17 18  2  0      
 18 19  1  0      
 19 20  2  0      
 15 20  1  0      
 20 21  1  0      
  8 21  1  0      
  7 22  1  0      
 22 23  2  0      
 23 24  1  0      
 24 25  2  0      
 25 26  1  0      
 26 27  2  0      
 22 27  1  0      
 26 28  1  0      
 28 29  1  0      
 29 30  1  0      
 30 31  1  0      
 31 32  1  0      
 28 32  1  0      
 32 33  1  0      
 33 34  1  0      
 34 35  2  0      
 35 36  1  0      
 31 36  1  0      
 33 37  1  0      
 37 38  1  0      
 38 39  1  0      
 28 39  1  0      
 39 40  1  0      
 25 40  1  0      
 40 41  1  0      
 38 42  1  0      
 42 43  2  0      
 42 44  1  0      
 44 45  1  0      
 38 46  1  0      
 37 47  1  0      
 47 48  1  0      
 48 49  2  0      
 48 50  1  0      
 33 51  1  0      
 51 52  1  0      
 23 53  1  0      
 53 54  1  0      
  7 55  1  0      
 55 56  2  0      
 55 57  1  0      
 57 58  1  0      
  3 59  1  0      
 60 61  1  0      
 61 62  2  0      
 61 63  2  0      
 61 64  1  0      
M  END
>  <Catalog Number> (1)
A3920

>  <Item Name> (1)
Vinblastine sulfate

>  <Formula> (1)
C46H60N4O13S

>  <MolWeight> (1)
909.05

>  <CAS Number> (1)
143-67-9

>  <Target> (1)
Autophagy

>  <URL> (1)
http://www.apexbt.com/search.php?catalog=A3920

$$$$

Untitled Document
  ChemDraw02181413222D
 11 12  0  0  0  0  0  0  0  0999 V2000
   -0.7145   -0.8591    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
   -1.3276    0.5179    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
    0.7145   -0.8591    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
   -0.1715    1.1854    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
    1.4289    0.3784    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7145   -0.0341    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.0000    0.3784    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.7145   -0.0341    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.0000   -1.2716    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4289   -1.2716    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.9920    1.2716    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
  6  1  1  0      
  9  1  1  0      
  1 10  1  0      
  2  6  2  0      
 11  2  1  0      
  3  8  1  0      
  9  3  2  0      
  7  4  1  0      
  4 11  2  0      
  5  8  1  0      
  7  6  1  0      
  8  7  2  0      
V    1 0
V    2 1
V    3 2
V    4 3
V    5 4
V    6 5
V    7 6
V    8 7
V    9 8
V   10 9
V   11 10
M  END
>  <Catalog Number> (1)
A8353

>  <Item Name> (1)
3-Methyladenine

>  <Formula> (1)
C6H7N5

>  <MolWeight> (1)
149.15

>  <CAS Number> (1)
5142-23-4

>  <Target> (1)
Autophagy

>  <URL> (1)
http://www.apexbt.com/search.php?catalog=A8353

$$$$

Untitled Document
  ChemDraw07031410452D
 30 31  0  0  0  0  0  0  0  0999 V2000
   -2.1732    0.6274    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.0866    0.0000    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -2.1732    1.8821    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.0000   -0.6274    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.5354   -1.2547    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -1.0866   -2.5094    0.0000 O   0  5  0  0  0  0  0  0  0  0  0  0
    0.0000   -1.8821    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.0000    1.8821    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7244   -1.8821    0.0000 N   0  3  0  0  0  0  0  0  0  0  0  0
   -0.7244    0.6274    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.0866    1.2547    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.0000    0.6274    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.0866    0.0000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7244    1.8821    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.3622    1.2547    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.8110    1.2547    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7244   -0.6274    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.3622    0.0000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.8110    0.0000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.0866    2.5094    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.0866    1.2547    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.0866   -1.2547    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.1732   -0.6274    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.8977    0.6274    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.8110   -1.2547    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4488   -0.6274    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.2599    1.2547    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.2599    0.0000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.1732   -0.6274    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.2599   -1.2547    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
  1 16  1  0      
  1 24  1  0      
  2 18  1  0      
  2 26  1  0      
  3 16  2  0      
  4 18  2  0      
  5 29  1  0      
  5 30  1  0      
  6  9  1  0      
  7  9  2  0      
 14  8  1  0      
  8 15  1  0      
  9 22  1  0      
 11 10  1  0      
 12 10  1  0      
 10 13  1  6      
 11 14  2  0      
 11 16  1  0      
 15 12  2  0      
 12 18  1  0      
 13 17  1  0      
 13 19  2  0      
 14 20  1  0      
 15 21  1  0      
 17 22  2  0      
 23 19  1  0      
 22 25  1  0      
 25 23  2  0      
 24 27  1  0      
 24 28  1  0      
 26 29  1  0      
M  CHG  2   6  -1   9   1
V    1 0
V    2 1
V    3 2
V    4 3
V    5 4
V    6 5
V    7 6
V    8 7
V    9 8
V   10 9
V   11 10
V   12 11
V   13 12
V   14 13
V   15 14
V   16 15
V   17 16
V   18 17
V   19 18
V   20 19
V   21 20
V   22 21
V   23 22
V   24 23
V   25 24
V   26 25
V   27 26
V   28 27
V   29 28
V   30 29
M  END
>  <Catalog Number> (1)
A8484

>  <Item Name> (1)
Nimodipine

>  <Formula> (1)
C21H26N2O7

>  <MolWeight> (1)
418.45

>  <CAS Number> (1)
66085-59-4

>  <Target> (1)
Autophagy

>  <URL> (1)
http://www.apexbt.com/search.php?catalog=A8484

$$$$

Untitled Document
  ChemDraw07031410462D
 21 23  0  0  0  0  0  0  0  0999 V2000
   -1.9654    1.8861    0.0000 S   0  0  0  0  0  0  0  0  0  0  0  0
   -0.6212    2.3638    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.8498   -2.2218    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.1218   -1.0892    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.1100   -0.5695    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
    1.1611   -0.2280    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
    0.9707   -1.4302    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
    0.1100    0.1135    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.7596    0.3246    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.2556    1.2387    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.3976    0.5706    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.9016    0.9927    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.7596   -0.7806    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.3940    1.4497    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7632    1.6957    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4128    1.4846    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.6238    0.8350    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.3069    0.8350    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.5179    1.4846    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.6388   -1.5722    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.5179   -2.3638    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
 16  1  1  0      
 19  1  1  0      
  2 15  2  0      
  3 20  1  0      
  3 21  1  0      
  4 20  2  0      
  5  8  1  0      
 13  5  1  0      
  6  9  1  0      
  6 13  2  0      
  7 13  1  0      
  7 20  1  0      
  8  9  1  0      
  8 11  2  0      
 12  9  2  0      
 11 10  1  0      
 10 14  2  0      
 10 15  1  0      
 14 12  1  0      
 15 16  1  0      
 16 17  2  0      
 17 18  1  0      
 18 19  2  0      
V    1 0
V    2 1
V    3 2
V    4 3
V    5 4
V    6 5
V    7 6
V    8 7
V    9 8
V   10 9
V   11 10
V   12 11
V   13 12
V   14 13
V   15 14
V   16 15
V   17 16
V   18 17
V   19 18
V   20 19
V   21 20
M  END
>  <Catalog Number> (1)
A8487

>  <Item Name> (1)
Nocodazole

>  <Formula> (1)
C14H11N3O3S

>  <MolWeight> (1)
301.32

>  <CAS Number> (1)
31430-18-9

>  <Target> (1)
Autophagy

>  <URL> (1)
http://www.apexbt.com/search.php?catalog=A8487

$$$$

Untitled Document
  ChemDraw07031411472D
 31 35  0  0  0  0  0  0  0  0999 V2000
   -0.6083    0.7269    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.2053    1.0759    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.8956   -1.1218    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -2.4144   -1.3402    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.6008   -2.0653    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.0038    1.7740    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.4144    1.0759    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -1.8173    0.7269    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -1.2128   -1.0182    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.6083   -1.3672    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.0038   -0.3202    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.2128   -0.3202    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.6008    0.0289    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.0038   -1.0182    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.6083    0.0289    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7534   -2.0500    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.7316   -1.4853    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4476   -2.1230    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.8505   -0.7343    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.2053   -0.3202    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.6008    0.7269    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.6008   -1.3672    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.2053   -1.0182    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.0038    0.3779    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.8098    0.0289    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.0038    1.0759    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.8098    0.7269    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.2447   -0.5172    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.2128    1.0759    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.2128    1.7740    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.6083    2.1230    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
 15  1  1  1      
  1 29  1  0      
  2 21  1  0      
  2 27  1  0      
  3 23  1  0      
  3 28  1  0      
  4 17  2  0      
  5 22  2  0      
  6 26  1  0      
  6 31  1  0      
  7 27  2  0      
  8 29  2  0      
  9 10  1  0      
  9 12  1  0      
  9 17  1  0      
  9 19  1  6      
 10 14  1  0      
 10 16  1  6      
 11 13  1  0      
 11 14  2  0      
 11 15  1  0      
 12 15  1  0      
 13 20  1  0      
 13 21  1  0      
 13 24  1  6      
 14 22  1  0      
 16 18  1  0      
 17 18  1  0      
 20 23  2  0      
 20 25  1  0      
 21 26  1  1      
 22 23  1  0      
 25 27  1  0      
 25 28  2  0      
 29 30  1  0      
V    1 0
V    2 1
V    3 2
V    4 3
V    5 4
V    6 5
V    7 6
V    8 7
V    9 8
V   10 9
V   11 10
V   12 11
V   13 12
V   14 13
V   15 14
V   16 15
V   17 16
V   18 17
V   19 18
V   20 19
V   21 20
V   22 21
V   23 22
V   24 23
V   25 24
V   26 25
V   27 26
V   28 27
V   29 28
V   30 29
V   31 30
M  END
>  <Catalog Number> (1)
A8544

>  <Item Name> (1)
Wortmannin

>  <Formula> (1)
C23H24O8

>  <MolWeight> (1)
428.43

>  <CAS Number> (1)
19545-26-7

>  <Target> (1)
Autophagy

>  <URL> (1)
http://www.apexbt.com/search.php?catalog=A8544

$$$$

Untitled Document
  ChemDraw01161710002D
 32 31  0  0  0  0  0  0  0  0999 V2000
   -4.2868    3.8559    0.0000 Cl  0  0  0  0  0  0  0  0  0  0  0  0
    2.8578    2.2059    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7145    2.6184    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
   -2.8578    1.3809    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
    0.7145    2.6184    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4289    2.2059    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.0000    2.2059    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.1434    2.6184    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.0000    1.3809    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.5723    2.6184    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8578    1.3809    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4289    2.2059    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.5723    0.9684    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.2868    2.2059    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.1434    2.6184    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4289    1.3809    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.8578    2.2059    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.1434    3.4434    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.1434    0.9684    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.5723    2.6184    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.8578    3.8559    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.5723    3.4434    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.2089   -0.6853    0.0000 P   0  0  0  0  0  0  0  0  0  0  0  0
   -0.6214   -1.3998    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.5056   -1.0977    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.2035    0.0292    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.9234   -0.2728    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.2089   -3.1414    0.0000 P   0  0  0  0  0  0  0  0  0  0  0  0
   -0.6214   -3.8559    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.5056   -3.5538    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.2035   -2.4269    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.9234   -2.7289    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
  1 22  1  0      
  2  8  1  0      
  2 10  1  0      
  2 11  1  0      
  3  7  1  0      
  3 12  1  0      
 17  4  1  0      
 19  4  2  0      
  5  6  1  0      
  5  7  1  0      
  6  8  1  0      
  7  9  1  1      
 10 14  1  0      
 11 13  1  0      
 12 15  1  0      
 16 12  2  0      
 15 17  1  0      
 15 18  2  0      
 19 16  1  0      
 20 17  2  0      
 18 21  1  0      
 22 20  1  0      
 21 22  2  0      
 23 24  1  0      
 23 25  1  0      
 23 26  1  0      
 23 27  2  0      
 28 29  1  0      
 28 30  1  0      
 28 31  1  0      
 28 32  2  0      
V    1 0
V    2 11
V    3 12
V    4 13
V    5 14
V    6 15
V    7 16
V    8 17
V    9 18
V   10 19
V   11 20
V   12 21
V   13 22
V   14 23
V   15 24
V   16 25
V   17 26
V   18 27
V   19 28
V   20 29
V   21 30
V   22 31
V   23 1
V   24 6
V   25 7
V   26 8
V   27 9
V   28 2
V   29 3
V   30 4
V   31 5
V   32 10
M  END
>  <Catalog Number> (1)
A8628

>  <Item Name> (1)
Chloroquine diphosphate

>  <Formula> (1)
C18H26ClN3.2H3PO4

>  <MolWeight> (1)
515.86

>  <CAS Number> (1)
50-63-5

>  <Target> (1)
Autophagy

>  <URL> (1)
http://www.apexbt.com/search.php?catalog=A8628

$$$$

Untitled Document
  ChemDraw06241609452D
 31 33  0  0  0  0  0  0  0  0999 V2000
   -2.2320   -3.5951    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.9045    2.8839    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.1865    3.5690    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.4864    3.5951    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.9045   -0.7503    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.4977   -0.0326    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.4864   -1.4615    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.6727   -0.0261    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.2659    1.4419    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.0228    2.1466    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.0340    1.4159    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4409    1.4354    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.6614   -1.4550    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4409    0.6982    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.2546   -0.7373    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.6727    2.1596    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4296    2.8643    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.2546    2.8708    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.2433   -2.1662    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.0228   -0.0130    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.2091    0.7112    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.2659    0.6916    0.0000 Br  0  0  0  0  0  0  0  0  0  0  0  0
   -2.6501   -2.8839    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
   -0.2091    1.4224    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
    1.0340    0.7177    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
   -0.1978   -0.0065    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4183   -2.1596    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.4977    2.1662    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.0115    3.5755    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.6614    3.5885    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4296   -0.7307    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
  6  5  2  0      
  7  5  1  0      
  8  6  1  0      
 12  9  2  0      
 12 10  1  0      
 13  7  2  0      
 14 11  2  0      
 15  8  2  0      
 15 13  1  0      
 16  9  1  0      
 17 10  2  0      
 18 16  2  0      
 18 17  1  0      
 19 13  1  0      
 20 14  1  0      
 22 14  1  0      
 23  1  1  0      
 23 19  2  0      
 24 11  1  0      
 24 21  2  0      
 25 12  1  0      
 25 21  1  0      
 26 20  2  0      
 26 21  1  0      
 27 19  1  0      
 28  2  1  0      
 28 16  1  0      
 29  3  1  0      
 29 17  1  0      
 30  4  1  0      
 30 18  1  0      
 31 15  1  0      
 31 20  1  0      
M  END
>  <Catalog Number> (1)
A8715

>  <Item Name> (1)
SBI-0206965

>  <Formula> (1)
C21H21BrN4O5

>  <MolWeight> (1)
489.32

>  <CAS Number> (1)
N/A

>  <Target> (1)
Autophagy

>  <URL> (1)
http://www.apexbt.com/search.php?catalog=A8715

$$$$

Untitled Document
  ChemDraw02031515482D
 30 33  0  0  0  0  0  0  0  0999 V2000
   -3.2151    0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.2151   -0.4125    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -2.5006   -0.8250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.7862   -0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.7862    0.4125    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
   -2.5006    0.8250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.5006    1.6500    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.0717    0.8250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.3572    0.4125    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
    0.3572    0.8250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.3572    1.6500    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
   -0.3572    2.0625    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.0717    1.6500    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.0717    0.4125    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
    1.7862    0.8250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.7862    1.6500    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.0717    2.0625    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.0717   -0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.3572   -0.8250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.3572   -0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.0717   -0.8250    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
   -1.0717   -1.6500    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.3572   -2.0625    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.3572   -1.6500    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.3572    2.8875    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.3572   -2.8875    0.0000 Cl  0  0  0  0  0  0  0  0  0  0  0  0
    2.5006    0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.0881   -0.3020    0.0000 F   0  0  0  0  0  0  0  0  0  0  0  0
    3.2151    0.0000    0.0000 F   0  0  0  0  0  0  0  0  0  0  0  0
    2.9131    1.1270    0.0000 F   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0      
  2  3  1  0      
  3  4  1  0      
  4  5  1  0      
  5  6  1  0      
  6  1  1  0      
  6  7  1  1      
  5  8  1  0      
  8  9  1  0      
  9 10  2  0      
 10 11  1  0      
 11 12  1  0      
 12 13  1  0      
 13  8  2  0      
 10 14  1  0      
 14 15  1  0      
 15 16  1  0      
 16 17  1  0      
 17 11  1  0      
 14 18  1  0      
 18 19  1  0      
 19 20  2  0      
 20 21  1  0      
 21 22  2  0      
 22 23  1  0      
 23 24  2  0      
 24 19  1  0      
 12 25  2  0      
 23 26  1  0      
 15 27  1  1      
 27 28  1  0      
 27 29  1  0      
 27 30  1  0      
M  STY  1   1 SUP
M  SLB  1   1   1
M  SAL   1  4  27  28  29  30
M  SBL   1  1  30
M  SMT   1 CF3
M  SBV   1  30   -0.7145    0.4125
M  END
>  <Catalog Number> (1)
A8883

>  <Item Name> (1)
SAR405

>  <Formula> (1)
C19H21ClF3N5O2

>  <MolWeight> (1)
443.85

>  <CAS Number> (1)
1523406-39-4

>  <Target> (1)
Autophagy

>  <URL> (1)
http://www.apexbt.com/search.php?catalog=A8883

$$$$

Untitled Document
  ChemDraw01161715172D
 15 14  0  0  0  0  0  0  0  0999 V2000
    0.2467   -0.4867    0.0000 S   0  0  0  0  0  0  0  0  0  0  0  0
   -0.1658   -1.2013    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.9612   -0.8992    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -1.1823   -1.3117    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.4678   -0.0743    0.0000 N   0  5  0  0  0  0  0  0  0  0  0  0
    1.8967    2.3711    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
    0.6593    0.2278    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.2467    0.9422    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4842    0.2278    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4842    1.6567    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.6593    1.6567    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.8967    0.9422    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.1823   -0.4867    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.8967   -0.0743    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.0661   -2.3711    0.0000 Na  0  3  0  0  0  0  0  0  0  0  0  0
  1  2  2  0      
  1  3  2  0      
  1  5  1  0      
  1  7  1  0      
  4 13  2  0      
  5 13  1  0      
  6 10  1  0      
  7  8  1  0      
  7  9  2  0      
  8 11  2  0      
 12  9  1  0      
 11 10  1  0      
 10 12  2  0      
 13 14  1  0      
M  CHG  2   5  -1  15   1
V    1 0
V    2 2
V    3 3
V    4 4
V    5 5
V    6 6
V    7 7
V    8 8
V    9 9
V   10 10
V   11 11
V   12 12
V   13 13
V   14 14
V   15 1
M  END
>  <Catalog Number> (1)
B1395

>  <Item Name> (1)
Sulfacetamide Sodium

>  <Formula> (1)
C8H10N2O3S.Na

>  <MolWeight> (1)
236.22

>  <CAS Number> (1)
127-56-0

>  <Target> (1)
Autophagy

>  <URL> (1)
http://www.apexbt.com/search.php?catalog=B1395

$$$$

Untitled Document
  ChemDraw02281417492D
 14 14  0  0  0  0  0  0  0  0999 V2000
    0.0000   -1.6070    0.0000 S   0  0  0  0  0  0  0  0  0  0  0  0
   -1.3917    0.8035    0.0000 S   0  0  0  0  0  0  0  0  0  0  0  0
    0.6958    0.4017    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
    1.3917   -0.8035    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
    0.0000    1.6070    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
    1.3917   -2.4105    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
   -1.3917    2.4105    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
    0.0000   -0.8035    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.6958    0.4017    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.6958   -0.4017    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.6958   -0.4017    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.0000    0.8035    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.6958   -2.0087    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.3917    1.6070    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
  1  8  1  0      
  1 13  1  0      
  2  9  1  0      
  2 14  1  0      
 11  3  2  0      
  3 12  1  0      
  4 11  1  0      
  5 12  1  0      
  6 13  3  0      
  7 14  3  0      
 10  8  2  0      
  8 11  1  0      
  9 10  1  0      
  9 12  2  0      
V    1 0
V    2 1
V    3 2
V    4 3
V    5 4
V    6 5
V    7 6
V    8 7
V    9 8
V   10 9
V   11 10
V   12 11
V   13 12
V   14 13
M  END
>  <Catalog Number> (1)
A8212

>  <Item Name> (1)
PR-619

>  <Formula> (1)
C7H5N5S2

>  <MolWeight> (1)
223.28

>  <CAS Number> (1)
2645-32-1

>  <Target> (1)
DUB

>  <URL> (1)
http://www.apexbt.com/search.php?catalog=A8212

$$$$

Untitled Document
  ChemDraw07031421552D
 27 29  0  0  0  0  0  0  0  0999 V2000
    1.4886   -2.0364    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.5794    0.2784    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.3354   -1.7765    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4421    2.6372    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -2.4006    2.0838    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.4006   -2.9709    0.0000 O   0  5  0  0  0  0  0  0  0  0  0  0
    1.5859   -3.7440    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.4836   -0.1297    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7435   -0.7134    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
    1.7834   -3.1363    0.0000 N   0  3  0  0  0  0  0  0  0  0  0  0
   -0.8031    0.4237    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.2847   -0.8215    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.1519   -0.1965    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.2686   -1.1410    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4421    0.4237    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.4836    0.9771    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.8685   -1.0814    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4421    1.5305    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.7616    0.9771    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.8031    1.5305    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.9353   -1.7169    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.4604   -2.1445    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.7616    2.0838    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.7203   -2.7282    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.3558   -2.6614    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.7616    3.1906    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4421    3.7440    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
 21  1  1  0      
 25  1  1  0      
  2 13  2  0      
  3 14  2  0      
  4 23  1  0      
  4 26  1  0      
  5 23  2  0      
  6 10  1  0      
  7 10  2  0      
  9  8  1  0      
  8 11  1  0      
 13  8  1  0      
 14  9  1  0      
 10 25  1  0      
 11 15  1  0      
 11 16  2  0      
 13 12  1  0      
 12 14  1  0      
 12 17  2  0      
 15 19  2  0      
 20 16  1  0      
 17 21  1  0      
 19 18  1  0      
 18 20  2  0      
 18 23  1  0      
 21 22  2  0      
 22 24  1  0      
 24 25  2  0      
 26 27  1  0      
M  CHG  2   6  -1  10   1
V    1 0
V    2 1
V    3 2
V    4 3
V    5 4
V    6 5
V    7 6
V    8 7
V    9 8
V   10 9
V   11 10
V   12 11
V   13 12
V   14 13
V   15 14
V   16 15
V   17 16
V   18 17
V   19 18
V   20 19
V   21 20
V   22 21
V   23 22
V   24 23
V   25 24
V   26 25
V   27 26
M  END
>  <Catalog Number> (1)
B1492

>  <Item Name> (1)
PYR-41

>  <Formula> (1)
C17H13N3O7

>  <MolWeight> (1)
371.3

>  <CAS Number> (1)
418805-02-4

>  <Target> (1)
E1 Activating

>  <URL> (1)
http://www.apexbt.com/search.php?catalog=B1492

$$$$

Untitled Document
  ChemDraw07031413252D
 26 29  0  0  0  0  0  0  0  0999 V2000
   -0.9453    0.3638    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
    0.3151   -1.8192    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
   -0.3151   -0.7277    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
   -0.9453   -1.8192    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
   -1.5755   -0.7277    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.9453   -0.3638    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.5755   -1.4554    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.3151    0.7277    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.3151   -1.4554    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.9453   -1.4554    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.3151    1.4554    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.2057   -0.3638    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.5755   -1.8192    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.2057   -1.8192    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.8359   -0.7277    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.8359   -1.4554    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.3151    1.8192    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.9453    1.8192    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.2057   -1.4554    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.5755   -2.5469    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.3151    2.5469    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.9453    2.5469    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8359   -1.8192    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.2057   -2.9108    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.3151    2.9108    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8359   -2.5469    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
  1  6  1  0      
  1  8  1  0      
  2  9  1  0      
  2 10  1  0      
  3  6  2  0      
  9  3  1  0      
  7  4  1  0      
  4  9  2  0      
  6  5  1  0      
  7  5  1  0      
  5 12  2  0      
 14  7  2  0      
  8 11  1  0      
 10 13  1  0      
 11 17  1  0      
 11 18  2  0      
 12 15  1  0      
 13 19  1  0      
 13 20  2  0      
 16 14  1  0      
 16 15  2  0      
 17 21  2  0      
 22 18  1  0      
 19 23  2  0      
 24 20  1  0      
 21 25  1  0      
 25 22  2  0      
 23 26  1  0      
 26 24  2  0      
V    1 0
V    2 1
V    3 2
V    4 3
V    5 4
V    6 5
V    7 6
V    8 7
V    9 8
V   10 9
V   11 10
V   12 11
V   13 12
V   14 13
V   15 14
V   16 15
V   17 16
V   18 17
V   19 18
V   20 19
V   21 20
V   22 21
V   23 22
V   24 23
V   25 24
V   26 25
M  END
>  <Catalog Number> (1)
A8629

>  <Item Name> (1)
DBeQ

>  <Formula> (1)
C22H20N4

>  <MolWeight> (1)
340.42

>  <CAS Number> (1)
177355-84-9

>  <Target> (1)
p97

>  <URL> (1)
http://www.apexbt.com/search.php?catalog=A8629

$$$$

Untitled Document
  ChemDraw07031414262D
 36 40  0  0  0  0  0  0  0  0999 V2000
   -2.3054   -1.6096    0.0000 S   0  0  0  0  0  0  0  0  0  0  0  0
    3.3474    1.8099    0.0000 S   0  0  0  0  0  0  0  0  0  0  0  0
   -0.3439   -0.3212    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.6518    1.2826    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.8747    2.1144    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4622   -0.9268    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
   -2.3622   -0.5261    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
   -1.9548   -0.0736    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
   -0.6838   -2.3372    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
   -2.9110   -1.6733    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.3184   -1.2208    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.2155   -2.2006    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.8747   -1.4685    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.8110   -2.0740    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.0578   -1.0534    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.3985   -0.3212    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.0097   -1.3342    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.8712   -0.0168    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.4306   -1.1461    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.1363   -1.9298    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.2381    0.5921    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.1834   -0.0168    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.2381   -0.0168    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.7654    0.8966    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.7108   -0.3212    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.7108    0.8966    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.1834    0.5921    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8200    1.5055    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.0219   -1.5535    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.2927    0.5921    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.7654    1.5055    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.7654   -0.3212    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8200    0.8966    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.2927    1.8099    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.1047   -2.1491    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.0429    2.3372    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
  1 10  1  0      
  1 15  1  0      
  2  4  2  0      
  2  5  2  0      
  2 28  1  0      
  2 36  1  0      
  3 18  1  0      
  3 22  1  0      
 15  6  1  0      
  6 16  1  0      
  6 17  1  0      
  8  7  1  0      
 15  7  2  0      
 16  8  2  0      
 20  9  2  0      
  9 35  1  0      
 10 11  1  0      
 10 12  1  0      
 11 13  1  0      
 14 12  1  0      
 13 14  1  0      
 16 18  1  0      
 19 17  2  0      
 17 20  1  0      
 29 19  1  0      
 21 23  1  0      
 21 24  1  0      
 21 26  2  0      
 25 22  1  0      
 22 27  2  0      
 23 25  2  0      
 23 32  1  0      
 24 30  1  0      
 24 31  2  0      
 27 26  1  0      
 33 28  1  0      
 28 34  2  0      
 29 35  2  0      
 30 33  2  0      
 34 31  1  0      
V    1 0
V    2 1
V    3 2
V    4 3
V    5 4
V    6 5
V    7 6
V    8 7
V    9 8
V   10 9
V   11 10
V   12 11
V   13 12
V   14 13
V   15 14
V   16 15
V   17 16
V   18 17
V   19 18
V   20 19
V   21 20
V   22 21
V   23 22
V   24 23
V   25 24
V   26 25
V   27 26
V   28 27
V   29 28
V   30 29
V   31 30
V   32 31
V   33 32
V   34 33
V   35 34
V   36 35
M  END
>  <Catalog Number> (1)
B2168

>  <Item Name> (1)
NMS-873

>  <Formula> (1)
C27H28N4O3S2

>  <MolWeight> (1)
520.67

>  <CAS Number> (1)
1418013-75-8

>  <Target> (1)
p97

>  <URL> (1)
http://www.apexbt.com/search.php?catalog=B2168

$$$$

Untitled Document
  ChemDraw02281418472D
 45 45  0  0  0  0  0  0  0  0999 V2000
   -6.8335    5.4929    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -6.4947    4.4672    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -5.4371    4.2479    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.7183    5.0541    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -5.0571    6.0798    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -6.1147    6.2991    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.6606    4.8347    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.3218    3.8091    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -2.2641    3.5897    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.5453    4.3960    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -1.9253    2.5641    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
   -0.8677    2.3447    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.1488    3.1510    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.5288    1.3191    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.2476    0.5128    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.5288    1.0997    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
   -0.4877    4.1766    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.9088    2.9316    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.6276    3.7378    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.8677    0.0741    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.1488   -0.7322    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.9253   -0.1453    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.6441    0.6609    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.2641   -1.1710    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
    0.4877   -1.7578    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.2311   -2.5641    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.2888   -2.3447    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.1077   -3.5897    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.6111   -4.3960    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.6687   -4.1766    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.2723   -5.4216    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.3299   -5.2022    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.3218   -1.3903    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.0406   -0.5841    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.6606   -2.4160    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.9418   -3.2222    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.7183   -2.6353    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
    5.0571   -3.6610    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.3383   -4.4672    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.1147   -3.8804    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.8335   -3.0741    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    6.4536   -4.9060    0.0000 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.6771   -5.4929    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.7348   -5.7123    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.9583   -6.2991    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  2  0      
  2  3  1  0      
  3  4  2  0      
  4  5  1  0      
  5  6  2  0      
  6  1  1  0      
  4  7  1  0      
  7  8  1  0      
  8  9  1  0      
  9 10  2  0      
  9 11  1  0      
 11 12  1  0      
 12 13  1  1      
 12 14  1  0      
 14 15  2  0      
 14 16  1  0      
 13 17  1  6      
 13 18  1  0      
 18 19  1  0      
 16 20  1  0      
 20 21  1  6      
 20 22  1  0      
 22 23  2  0      
 22 24  1  0      
 21 25  1  0      
 25 26  1  0      
 26 27  2  0      
 26 28  1  0      
 28 29  1  0      
 29 30  1  0      
 29 31  1  0      
 29 32  1  0      
 24 33  1  0      
 33 34  1  1      
 33 35  1  0      
 35 36  2  0      
 35 37  1  0      
 37 38  1  0      
 38 39  1  6      
 38 40  1  0      
 40 41  2  0      
 40 42  1  0      
 39 43  1  0      
 43 44  1  0      
 43 45  1  0      
M  END
>  <Catalog Number> (1)
A1900

>  <Item Name> (1)
PSI

>  <Formula> (1)
C32H50N4O8

>  <MolWeight> (1)
618.76

>  <CAS Number> (1)
158442-41-2

>  <Target> (1)
Proteasome

>  <URL> (1)
http://www.apexbt.com/search.php?catalog=A1900

$$$$

Untitled Document
  ChemDraw02281418492D
 52 55  0  0  0  0  0  0  0  0999 V2000
    5.6064   -5.1102    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.6712   -5.0600    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.2470   -4.2251    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.7580   -3.4402    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
    5.6932   -3.4903    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.1174   -4.3253    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.3338   -2.6052    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.3986   -2.5551    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8875   -3.3399    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.9744   -1.7201    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
    2.0391   -1.6700    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.5281   -2.4548    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.5929   -2.4047    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.0819   -3.1896    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.5061   -4.0246    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.0049   -4.8094    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.9402   -4.7593    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.3644   -3.9243    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.8533   -3.1395    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.6149   -0.8350    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.6797   -0.7849    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
    2.1260   -0.0501    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.2555    0.0501    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.7665    0.8350    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.3423    1.6700    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.5929    1.7201    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.8533    2.4548    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.6797    0.1002    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.1039    0.9352    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
   -1.1907   -0.6846    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -2.0391    0.9854    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.5502    0.2005    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.4854    0.2506    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.9964   -0.5342    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.9316   -0.4841    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -5.3558    0.3509    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.8448    1.1357    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.9096    1.0856    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.4633    1.8203    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.3986    1.8705    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
   -1.9523    2.6052    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -3.8228    2.7055    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.3117    3.4903    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.7580    2.7556    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.7359    4.3253    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.6712    4.3754    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.2249    5.1102    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -5.1822    3.5906    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -5.2690    1.9707    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -6.1174    3.6407    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -5.6064    4.4255    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.2470    3.5404    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0      
  2  3  1  0      
  3  4  1  0      
  4  5  1  0      
  5  6  1  0      
  6  1  1  0      
  4  7  1  0      
  7  8  1  0      
  8  9  2  0      
  8 10  1  0      
 10 11  1  0      
 11 12  1  1      
 12 13  1  0      
 13 14  1  0      
 14 15  2  0      
 15 16  1  0      
 16 17  2  0      
 17 18  1  0      
 18 19  2  0      
 19 14  1  0      
 11 20  1  0      
 20 21  1  0      
 20 22  2  0      
 21 23  1  0      
 23 24  1  6      
 24 25  1  0      
 25 26  1  0      
 25 27  1  0      
 23 28  1  0      
 28 29  1  0      
 28 30  2  0      
 29 31  1  0      
 31 32  1  1      
 32 33  1  0      
 33 34  2  0      
 34 35  1  0      
 35 36  2  0      
 36 37  1  0      
 37 38  2  0      
 38 33  1  0      
 31 39  1  0      
 39 40  1  0      
 39 41  2  0      
 40 42  1  0      
 42 43  1  6      
 42 44  1  0      
 43 45  1  0      
 45 46  1  0      
 45 47  1  0      
 44 48  1  0      
 44 49  2  0      
 48 50  1  0      
 50 51  1  0      
 51 48  1  0      
 48 52  1  6      
M  END
>  <Catalog Number> (1)
A1933

>  <Item Name> (1)
Carfilzomib (PR-171)

>  <Formula> (1)
C40H57N5O7

>  <MolWeight> (1)
719.91

>  <CAS Number> (1)
868540-17-4

>  <Target> (1)
Proteasome

>  <URL> (1)
http://www.apexbt.com/search.php?catalog=A1933

$$$$

Untitled Document
  ChemDraw06111414102D
 37 39  0  0  0  0  0  0  0  0999 V2000
   -4.4933    3.2524    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.6719    3.3126    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.3633    3.0492    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.4584    3.8687    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.2671    4.0315    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
   -3.0454    2.6267    0.0000 S   0  0  0  0  0  0  0  0  0  0  0  0
   -1.6218    2.6907    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.9406    3.1536    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -1.5616    1.8693    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
   -0.8201    1.5108    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.1389    1.9737    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7598    0.6894    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.0183    0.3309    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4410    0.2265    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.6026    1.6152    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.0419   -0.4905    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.6393   -0.9533    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.7834   -0.8490    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.5790   -1.7747    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -1.2602   -2.2376    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.8437   -1.6703    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
    1.4646   -0.3861    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.5851   -2.0288    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.6454   -2.8502    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.2663   -1.5660    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.0078   -1.9245    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.6902   -1.4608    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.4329   -1.8199    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.4933   -2.6427    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.8109   -3.1064    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.0682   -2.7472    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.3869   -3.2087    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.9642   -3.3131    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.1296   -3.5678    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.4473   -4.0315    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.8478   -3.8332    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.2838    2.0781    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0      
  3  4  2  0      
  4  5  1  0      
  5  2  2  0      
  2  6  1  0      
  6  3  1  0      
  3  7  1  0      
  7  8  2  0      
  7  9  1  0      
  9 10  1  0      
 10 11  1  1      
 10 12  1  0      
 12 13  1  0      
 12 14  2  0      
 11 15  1  0      
 13 16  1  0      
 16 17  1  6      
 16 18  1  0      
 17 19  1  0      
 19 20  1  0      
 18 21  1  0      
 18 22  2  0      
 21 23  1  0      
 23 24  1  0      
 23 25  1  1      
 25 26  1  0      
 26 27  2  0      
 27 28  1  0      
 28 29  2  0      
 29 30  1  0      
 30 31  2  0      
 31 26  1  0      
 24 32  1  0      
 24 33  2  0      
 32 34  1  0      
 32 35  1  0      
 34 35  1  0      
 32 36  1  6      
 15 37  1  0      
M  END
>  <Catalog Number> (1)
A1934

>  <Item Name> (1)
Oprozomib (ONX-0912)

>  <Formula> (1)
C25H32N4O7S

>  <MolWeight> (1)
532.61

>  <CAS Number> (1)
935888-69-0

>  <Target> (1)
Proteasome

>  <URL> (1)
http://www.apexbt.com/search.php?catalog=A1934

$$$$

Untitled Document
  ChemDraw02281418502D
 35 35  0  0  0  0  0  0  0  0999 V2000
   -3.5176    0.6196    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -2.6935    0.6571    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.2489   -0.0378    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4247   -0.0002    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.9801   -0.6952    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.1560   -0.6576    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
    0.2886   -1.3525    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.1128   -1.3149    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.5574   -2.0099    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
    2.3815   -1.9723    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8262   -2.6672    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.6503   -2.6297    0.0000 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.9620    1.3141    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.5834    2.0448    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.7592    2.0824    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.3797    2.8149    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.8243    3.5098    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.6485    3.4722    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.0280    2.7397    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.3142    1.3892    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -1.0454    0.7319    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.2218    0.7694    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.2217    0.0762    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.1568    1.5001    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.3594   -1.4272    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.0907   -2.0846    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.3537   -2.7791    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.0249   -3.5098    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.1758   -2.7416    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4921   -0.5829    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.7608   -1.2402    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.5845   -1.2027    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.0280   -1.8959    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.9631   -0.4720    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.4469   -3.3993    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0      
  2  3  1  0      
  4  3  1  1      
  4  5  1  0      
  5  6  1  0      
  7  6  1  6      
  7  8  1  0      
  8  9  1  0      
 10  9  1  1      
 10 11  1  0      
 11 12  1  0      
  1 13  1  0      
 13 14  1  0      
 14 15  2  0      
 15 16  1  0      
 16 17  2  0      
 17 18  1  0      
 18 19  2  0      
 19 14  1  0      
  2 20  2  0      
  4 21  1  0      
 21 22  1  0      
 22 23  1  0      
 22 24  1  0      
  5 25  2  0      
  7 26  1  0      
 26 27  1  0      
 27 28  1  0      
 27 29  1  0      
  8 30  2  0      
 10 31  1  0      
 31 32  1  0      
 32 33  1  0      
 32 34  1  0      
 11 35  2  0      
M  END
>  <Catalog Number> (1)
A2585

>  <Item Name> (1)
MG-132

>  <Formula> (1)
C26H41N3O5

>  <MolWeight> (1)
475.6

>  <CAS Number> (1)
133407-82-6

>  <Target> (1)
Proteasome

>  <URL> (1)
http://www.apexbt.com/search.php?catalog=A2585

$$$$

Untitled Document
  ChemDraw06111414262D
 34 38  0  0  0  0  0  0  0  0999 V2000
   -3.4049   -1.4036    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.4049   -2.5270    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.4320   -3.0885    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4592   -2.5270    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4592   -1.4036    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.4320   -0.8420    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.4864   -3.0885    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.4864   -2.5270    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.4864   -1.4036    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.4864   -0.8420    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.3777   -0.8420    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -4.3777   -3.0885    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -2.4320   -4.2119    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4593   -0.8420    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4593    0.2813    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.4864    0.8431    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.4864    0.2813    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.4320   -1.4036    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.4049   -0.8420    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.4049    0.2813    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.4320    0.8431    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.3777    0.8431    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.3777    1.9664    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.4049    2.5281    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.4320    1.9664    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4593   -1.9653    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4593    1.4048    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.4320   -0.2802    0.0000 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.3777   -0.2802    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.4049    3.6507    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.3770    4.2119    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.4327    4.2119    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.4864   -1.9653    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.3777    3.0898    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0      
  2  3  2  0      
  3  4  1  0      
  4  5  1  0      
  5  6  2  0      
  6  1  1  0      
  4  7  2  0      
  7  8  1  0      
  8  9  2  0      
  9 10  1  0      
 10  5  1  0      
  1 11  2  0      
  2 12  1  0      
  3 13  1  0      
  9 14  1  0      
 14 15  1  0      
 15 16  1  0      
 16 17  1  0      
 17 10  1  0      
 14 18  1  0      
 18 19  1  0      
 19 20  1  0      
 20 21  1  0      
 21 15  1  0      
 20 22  1  0      
 22 23  1  0      
 23 24  1  0      
 24 25  1  0      
 25 21  1  0      
 14 26  1  1      
 15 27  1  6      
 21 28  1  1      
 20 29  1  1      
 24 30  1  0      
 30 31  1  0      
 30 32  2  0      
 10 33  1  1      
 24 34  1  1      
M  END
>  <Catalog Number> (1)
A2604

>  <Item Name> (1)
Celastrol

>  <Formula> (1)
C29H38O4

>  <MolWeight> (1)
450.61

>  <CAS Number> (1)
34157-83-0

>  <Target> (1)
Proteasome

>  <URL> (1)
http://www.apexbt.com/search.php?catalog=A2604

$$$$

Untitled Document
  ChemDraw02281418512D
 39 39  0  0  0  0  0  0  0  0999 V2000
    3.7393   -3.0018    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.3590   -2.2697    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
    4.5635   -3.0385    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.2954   -3.6972    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.8028   -1.5743    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.5348   -2.2330    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.0909   -2.9284    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.1545   -1.5008    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.2667   -2.8918    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.4713   -3.6606    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.8229   -3.5872    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.5983   -0.8054    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.3303   -1.4641    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
    0.9500   -0.7321    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.1258   -0.6954    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.3938   -0.0366    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.0135    0.6955    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.2180   -0.0733    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4573    1.3909    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.3181   -1.3908    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.2546    0.0367    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
   -1.0787    0.0734    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4591    0.8055    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.5225   -0.6221    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.1422   -1.3542    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -2.3467   -0.5854    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.0152    1.5009    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -2.2833    0.8422    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
   -2.6636    1.5743    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.4877    1.6109    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.2198    2.2697    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.6000    3.0018    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.1562    3.6972    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.4243    3.0385    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.8681    2.3430    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.9316    0.9155    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -3.8315    3.1672    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -4.5635    2.7868    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.1360    2.7234    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0      
  1  3  1  0      
  1  4  2  0      
  2  5  1  0      
  6  2  1  1      
  6  7  1  0      
  6  8  1  0      
  7  9  1  0      
  7 10  1  1      
  9 11  1  0      
  8 12  2  0      
  8 13  1  0      
 14 13  1  6      
 14 15  1  0      
 14 16  1  0      
 16 17  1  0      
 16 18  1  6      
 17 19  1  0      
 15 20  2  0      
 15 21  1  0      
 22 21  1  1      
 22 23  1  0      
 22 24  1  0      
 24 25  1  6      
 24 26  1  0      
 23 27  2  0      
 23 28  1  0      
 29 28  1  0      
 29 30  1  0      
 29 31  1  6      
 31 32  1  0      
 32 33  1  0      
 32 34  1  0      
 30 35  1  0      
 30 36  2  0      
 35 37  1  1      
 37 38  1  0      
 38 35  1  0      
 35 39  1  6      
M  END
>  <Catalog Number> (1)
A2606

>  <Item Name> (1)
Epoxomicin

>  <Formula> (1)
C28H50N4O7

>  <MolWeight> (1)
554.7

>  <CAS Number> (1)
134381-21-8

>  <Target> (1)
Proteasome

>  <URL> (1)
http://www.apexbt.com/search.php?catalog=A2606

$$$$

Untitled Document
  ChemDraw02281418512D
 34 34  0  0  0  0  0  0  0  0999 V2000
   -4.5645    3.4500    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.3952    2.6427    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.6115    2.3857    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.9970    2.9359    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.1663    3.7432    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.9500    4.0002    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.2133    2.6789    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.0440    1.8716    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -1.2602    1.6145    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.0910    0.8073    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
   -0.3072    0.5502    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.1380   -0.2570    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.6458   -0.5141    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
   -0.6458    2.1648    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.3072    1.1004    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.0910    0.8434    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.2602    0.0361    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.7055    1.3936    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.8150   -1.3214    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7525   -0.8073    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.2005   -1.8716    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.3698   -2.6789    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.1536   -2.9359    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.2447   -3.2291    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.5988   -1.5784    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.7680   -2.3857    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
    2.2133   -1.0282    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.5518   -2.6427    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.7210   -3.4500    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.1663   -2.0925    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.9500   -2.3496    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.5645   -1.7993    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.5048   -3.7070    0.0000 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.1066   -4.0002    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  2  0      
  2  3  1  0      
  3  4  2  0      
  4  5  1  0      
  5  6  2  0      
  6  1  1  0      
  4  7  1  0      
  7  8  1  0      
  8  9  1  0      
 10 11  1  0      
  9 10  1  0      
 11 12  1  0      
 12 13  1  0      
  9 14  2  0      
 11 15  1  1      
 15 16  1  0      
 16 17  1  0      
 16 18  1  0      
 13 19  1  0      
 12 20  2  0      
 19 21  1  6      
 21 22  1  0      
 22 23  1  0      
 22 24  1  0      
 19 25  1  0      
 25 26  1  0      
 25 27  2  0      
 26 28  1  0      
 28 29  1  0      
 28 30  1  1      
 30 31  1  0      
 31 32  1  0      
 29 33  1  0      
 29 34  2  0      
M  END
>  <Catalog Number> (1)
A2612

>  <Item Name> (1)
MG-115

>  <Formula> (1)
C25H39N3O5

>  <MolWeight> (1)
461.59

>  <CAS Number> (1)
 

>  <Target> (1)
Proteasome

>  <URL> (1)
http://www.apexbt.com/search.php?catalog=A2612

$$$$

Untitled Document
  ChemDraw02281418512D
 28 29  0  0  0  0  0  0  0  0999 V2000
   -3.5723   -0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.5723   -1.2375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.8578   -1.6500    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
   -2.1433   -1.2375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.1433   -0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.8578    0.0000    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4289    0.0000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7145   -0.4125    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4289    0.8250    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.0000    0.0000    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.7145   -0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.0000    0.8250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.7145    1.2375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4289    0.8250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.1433    1.2375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.1433    2.0624    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4289    2.4749    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.7145    2.0624    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.7145   -1.2375    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.4289    0.0000    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
    2.1433   -0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8578    0.0000    0.0000 B   0  0  0  0  0  0  0  0  0  0  0  0
    2.1433   -1.2375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8578   -1.6500    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8578   -2.4749    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.5723   -1.2375    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.5723   -0.4125    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.8578    0.8250    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  2  0      
  2  3  1  0      
  3  4  2  0      
  4  5  1  0      
  5  6  2  0      
  6  1  1  0      
  5  7  1  0      
  7  8  1  0      
  7  9  2  0      
  8 10  1  0      
 10 11  1  0      
 10 12  1  1      
 12 13  1  0      
 13 14  2  0      
 14 15  1  0      
 15 16  2  0      
 16 17  1  0      
 17 18  2  0      
 18 13  1  0      
 11 19  2  0      
 11 20  1  0      
 20 21  1  0      
 21 22  1  0      
 21 23  1  6      
 23 24  1  0      
 24 25  1  0      
 24 26  1  0      
 22 27  1  0      
 22 28  1  0      
M  END
>  <Catalog Number> (1)
A2614

>  <Item Name> (1)
Bortezomib (PS-341)

>  <Formula> (1)
C19H25BN4O4

>  <MolWeight> (1)
384.24

>  <CAS Number> (1)
179324-69-7

>  <Target> (1)
Proteasome

>  <URL> (1)
http://www.apexbt.com/search.php?catalog=A2614

$$$$

Untitled Document
  ChemDraw02251418422D
 34 35  0  0  0  0  0  0  0  0999 V2000
   -3.2099   -1.8829    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.9106   -1.4683    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.9106   -0.6391    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.2099   -0.2245    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.5047   -0.6391    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.5092   -1.4683    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.2099   -2.7066    0.0000 Cl  0  0  0  0  0  0  0  0  0  0  0  0
   -3.2099    0.5991    0.0000 Cl  0  0  0  0  0  0  0  0  0  0  0  0
   -1.7958   -1.8801    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.0825   -1.4683    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
   -0.3692   -1.8801    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.3441   -1.4683    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.0574   -1.8801    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
    1.7707   -1.4683    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.7707   -0.6446    0.0000 B   0  0  0  0  0  0  0  0  0  0  0  0
    1.0670   -0.2433    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -1.7958   -2.7038    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.3441   -0.6446    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.4840   -1.8801    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.1973   -1.4683    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.9106   -1.8801    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.1973   -0.6446    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.4874   -0.2360    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.5003    0.5740    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.2136    0.9859    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.7966    0.9753    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.0800    0.5666    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.2563    0.5666    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.6681    1.2799    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.1555    1.2799    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.1555   -0.1467    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.0800    1.9933    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.6681    2.7066    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.9036    1.9933    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  2  0      
  2  3  1  0      
  3  4  2  0      
  4  5  1  0      
  5  6  2  0      
  6  1  1  0      
  1  7  1  0      
  4  8  1  0      
  6  9  1  0      
  9 10  1  0      
 10 11  1  0      
 11 12  1  0      
 12 13  1  0      
 13 14  1  0      
 14 15  1  6      
 15 16  1  0      
  9 17  2  0      
 12 18  2  0      
 14 19  1  0      
 20 21  1  0      
 19 20  1  0      
 20 22  1  0      
 15 23  1  0      
 23 24  1  0      
 24 25  2  0      
 24 26  1  0      
 26 27  1  0      
 27 28  1  0      
 16 27  1  0      
 27 29  1  0      
 28 30  1  0      
 28 31  2  0      
 29 32  1  0      
 32 33  1  0      
 32 34  2  0      
M  END
>  <Catalog Number> (1)
A4007

>  <Item Name> (1)
MLN9708

>  <Formula> (1)
C20H23BCl2N2O9

>  <MolWeight> (1)
517.1

>  <CAS Number> (1)
1201902-80-8

>  <Target> (1)
Proteasome

>  <URL> (1)
http://www.apexbt.com/search.php?catalog=A4007

$$$$

Untitled Document
  ChemDraw07041410492D
 23 23  0  0  0  0  0  0  0  0999 V2000
   -1.8929    0.3279    0.0000 Cl  0  0  0  0  0  0  0  0  0  0  0  0
   -3.4073   -2.2951    0.0000 Cl  0  0  0  0  0  0  0  0  0  0  0  0
    1.5144    2.2951    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.3786    1.6393    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.0000    0.9836    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7572   -1.6393    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.1358    0.3279    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7572   -0.3279    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
    2.6501    1.6393    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.2715    0.9836    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.5144    0.9836    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.2715    2.2951    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.4073    1.6393    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.3786    0.3279    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.0000   -0.3279    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.1358   -0.9836    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.8929   -0.9836    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.2715   -0.3279    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.2715   -1.6393    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.0287   -1.6393    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.0287   -0.3279    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.4073   -0.9836    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.1358    1.6393    0.0000 B   0  0  0  0  0  0  0  0  0  0  0  0
  1 18  1  0      
  2 20  1  0      
  3 23  1  0      
  4 23  1  0      
  5 14  2  0      
  6 16  2  0      
 11  7  1  6      
  7 14  1  0      
  8 15  1  0      
  8 16  1  0      
  9 10  1  0      
  9 12  1  0      
  9 13  1  0      
 10 11  1  0      
 11 23  1  0      
 14 15  1  0      
 16 17  1  0      
 17 18  1  0      
 17 19  2  0      
 18 21  2  0      
 20 19  1  0      
 22 20  2  0      
 21 22  1  0      
V    1 0
V    2 1
V    3 2
V    4 3
V    5 4
V    6 5
V    7 6
V    8 7
V    9 8
V   10 9
V   11 10
V   12 11
V   13 12
V   14 13
V   15 14
V   16 15
V   17 16
V   18 17
V   19 18
V   20 19
V   21 20
V   22 21
V   23 22
M  END
>  <Catalog Number> (1)
A4008

>  <Item Name> (1)
MLN2238

>  <Formula> (1)
C14H19BCl2N2O4

>  <MolWeight> (1)
361

>  <CAS Number> (1)
1072833-77-2

>  <Target> (1)
Proteasome

>  <URL> (1)
http://www.apexbt.com/search.php?catalog=A4008

$$$$

Untitled Document
  ChemDraw06111415022D
 30 31  0  0  0  0  0  0  0  0999 V2000
   -1.0907   -2.2654    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -1.7862   -0.1964    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
   -1.0831   -1.4405    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.7938   -1.0214    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.5120   -1.4273    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.4969    0.2227    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.2227   -1.0082    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.2151   -0.1833    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.4893    1.0476    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.1999    1.4667    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.7710    1.4535    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.1924    2.2917    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.7634    2.2785    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.4741    2.6976    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.3649   -1.0346    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
    0.3458   -1.4536    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.0640   -1.0477    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.3382   -2.2786    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.3800   -2.6845    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.0488   -2.6976    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.7747   -1.4667    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.0716   -0.2227    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
    1.7898    0.1832    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.7974    1.0068    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.5144    1.4120    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.0879    1.4251    0.0000 B   0  0  0  0  0  0  0  0  0  0  0  0
    0.3721    1.0206    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.0955    2.2473    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.2227    0.9944    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.5220    2.2342    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
  1  3  2  0      
  2  4  1  0      
  2  6  2  0      
  3  4  1  0      
  4  5  2  0      
  5  7  1  0      
  6  8  1  0      
  6  9  1  0      
  7  8  2  0      
  9 10  2  0      
  9 11  1  0      
 10 12  1  0      
 11 13  2  0      
 12 14  2  0      
 13 14  1  0      
  3 15  1  0      
 16 15  1  6      
 16 17  1  0      
 16 18  1  0      
 18 19  1  0      
 18 20  1  6      
 17 21  2  0      
 17 22  1  0      
 22 23  1  0      
 23 24  1  0      
 24 25  1  6      
 24 26  1  0      
 26 27  1  0      
 26 28  1  0      
 25 29  1  0      
 25 30  1  0      
M  END
>  <Catalog Number> (1)
A4009

>  <Item Name> (1)
CEP-18770

>  <Formula> (1)
C21H28BN3O5

>  <MolWeight> (1)
413.3

>  <CAS Number> (1)
847499-27-8

>  <Target> (1)
Proteasome

>  <URL> (1)
http://www.apexbt.com/search.php?catalog=A4009

$$$$

Untitled Document
  ChemDraw02281418542D
 42 45  0  0  0  0  0  0  0  0999 V2000
   -4.7432    4.2875    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -5.1558    3.5731    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -4.7435    2.8586    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.9185    2.8584    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
   -3.5058    3.5727    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.9182    4.2873    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.5062    2.1438    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.6812    2.1436    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.2685    2.8580    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -2.2688    1.4290    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4438    1.4288    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.0312    2.1432    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.0315    0.7143    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4442   -0.0001    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.2065    0.7141    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
    0.2058   -0.0005    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.2068   -0.7149    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.0308   -0.0007    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4435    0.7137    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.4432   -0.7152    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
    0.2055   -1.4294    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.2072   -2.1438    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.2052   -2.8584    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.0302   -2.8586    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4428   -2.1442    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.0305   -1.4296    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4425   -3.5731    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.0298   -4.2875    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.2682   -0.7154    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.6808   -0.0011    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.6805   -1.4300    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.2678   -2.1444    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.5055   -1.4302    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.5058   -0.0013    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.9182   -0.7158    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.7432   -0.7160    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.1558   -0.0017    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.7435    0.7129    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.9185    0.7131    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.0887   -2.0137    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.3024   -1.2169    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.2922   -0.6333    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0      
  2  3  1  0      
  3  4  1  0      
  4  5  1  0      
  5  6  1  0      
  6  1  1  0      
  4  7  1  0      
  7  8  1  0      
  8  9  2  0      
  8 10  1  0      
 10 11  1  0      
 11 12  1  1      
 11 13  1  0      
 13 14  2  0      
 13 15  1  0      
 15 16  1  0      
 16 17  1  6      
 16 18  1  0      
 18 19  2  0      
 18 20  1  0      
 17 21  1  0      
 21 22  2  0      
 22 23  1  0      
 23 24  2  0      
 24 25  1  0      
 25 26  2  0      
 26 21  1  0      
 24 27  1  0      
 27 28  1  0      
 29 30  1  1      
 20 29  1  0      
 29 31  1  0      
 31 32  2  0      
 31 33  1  0      
 30 34  1  0      
 34 35  2  0      
 35 36  1  0      
 36 37  2  0      
 37 38  1  0      
 38 39  2  0      
 39 34  1  0      
 33 40  1  0      
 40 41  1  0      
 41 33  1  0      
 33 42  1  1      
M  END
>  <Catalog Number> (1)
A4011

>  <Item Name> (1)
ONX-0914 (PR-957)

>  <Formula> (1)
C31H40N4O7

>  <MolWeight> (1)
580.67

>  <CAS Number> (1)
960374-59-8

>  <Target> (1)
Proteasome

>  <URL> (1)
http://www.apexbt.com/search.php?catalog=A4011

$$$$

Untitled Document
  ChemDraw06111415132D
 26 29  0  0  0  0  0  0  0  0999 V2000
   -1.7696    1.1780    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.2984    0.1425    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.1949   -0.1346    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.7097    0.5553    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.7343    1.6927    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.1396    2.4211    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.2539    2.1921    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.6824   -0.0348    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.6797    0.5126    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.7044    1.6500    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.7317    2.2400    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.0498   -1.2630    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.0000   -1.7015    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.9046   -1.0116    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.6802    1.5059    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.3523    0.4165    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.8439    2.8244    0.0000 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.7563    3.3768    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.7284    2.7871    0.0000 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.7193   -0.5011    0.0000 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.9394   -2.1487    0.0000 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.9068   -1.5500    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.0347   -2.8386    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.0363   -3.3768    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.9744   -0.9633    0.0000 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.9068    1.1432    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0      
  2  3  1  0      
  3  4  1  0      
  4  5  1  0      
  5  6  1  0      
  6  7  1  0      
  7  1  1  0      
  4  8  1  0      
  8  9  1  0      
  9 10  1  0      
 10 11  1  0      
 11  5  1  0      
  3 12  1  6      
 12 13  1  0      
 13 14  1  0      
 14  8  1  0      
  1 15  1  6      
 15 16  1  0      
  4 16  1  6      
  5 17  1  6      
 11 18  1  6      
 11 19  1  1      
  8 20  1  6      
 14 21  1  6      
 14 22  1  1      
 13 23  1  1      
 23 24  1  0      
  3 25  1  1      
  1 26  1  1      
M  END
>  <Catalog Number> (1)
A4014

>  <Item Name> (1)
Artemether (SM-224)

>  <Formula> (1)
C16H26O5

>  <MolWeight> (1)
298.4

>  <CAS Number> (1)
71963-77-4

>  <Target> (1)
Proteasome

>  <URL> (1)
http://www.apexbt.com/search.php?catalog=A4014

$$$$

Untitled Document
  ChemDraw02281419022D
 28 30  0  0  0  0  0  0  0  0999 V2000
   -2.6215    2.5345    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.3370    1.7600    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.5241    1.6192    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.9957    2.2528    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.2802    3.0272    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.0931    3.1680    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.4344    2.6753    0.0000 B   0  0  0  0  0  0  0  0  0  0  0  0
   -3.7188    3.4497    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -3.9628    2.0417    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.1828    2.1120    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.1017    1.3376    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.9146    1.1967    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.4267    0.7040    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.1422   -0.0704    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
    1.1991    0.4223    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4430    1.8303    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.0120    0.2815    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.6707   -0.2112    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.6707   -0.7040    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.2964   -0.4929    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.7680   -1.1265    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.0525   -1.9009    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8654   -2.0417    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.3938   -1.4081    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.1093   -0.6337    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.1499   -2.8161    0.0000 B   0  0  0  0  0  0  0  0  0  0  0  0
    3.9628   -2.9569    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.6215   -3.4497    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  2  0      
  2  3  1  0      
  3  4  2  0      
  4  5  1  0      
  5  6  2  0      
  6  1  1  0      
  1  7  1  0      
  7  8  1  0      
  7  9  1  0      
  4 10  1  0      
 11 12  1  0      
 11 13  1  0      
 13 14  1  0      
 12 15  1  0      
 12 16  2  0      
 15 17  2  0      
 15 18  1  0      
 18 14  1  0      
 14 19  1  0      
 17 20  1  0      
 20 21  2  0      
 21 22  1  0      
 22 23  2  0      
 23 24  1  0      
 24 25  2  0      
 25 20  1  0      
 23 26  1  0      
 26 27  1  0      
 26 28  1  0      
 10 11  2  0      
M  END
>  <Catalog Number> (1)
A8163

>  <Item Name> (1)
AM 114

>  <Formula> (1)
C20H21B2NO5

>  <MolWeight> (1)
377.01

>  <CAS Number> (1)
856849-35-9

>  <Target> (1)
Proteasome

>  <URL> (1)
http://www.apexbt.com/search.php?catalog=A8163

$$$$

Untitled Document
  ChemDraw02281419042D
 28 28  0  0  0  0  0  0  0  0999 V2000
   -0.5571    0.8730    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.2467    1.0092    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4735    1.6745    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.1631    1.8107    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.3899    2.4760    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.0795    2.6122    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.5422    2.0831    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.0943    1.4021    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.3303    0.2077    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
   -3.3063    3.2775    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.5861   -0.5938    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.3593    0.0715    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.8221    0.6006    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.1234   -1.1229    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.2757   -0.7300    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
    2.3990   -1.5724    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.5025   -1.3953    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.9010   -2.0831    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.1278   -2.7484    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.6650   -3.2775    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8617   -1.0433    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.8174   -2.8846    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.9605   -2.4645    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.6258   -2.2377    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.4896   -2.9273    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.3154   -2.3739    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.5422   -3.0392    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.5116    0.4644    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0      
  2  3  1  0      
  3  4  1  0      
  4  5  1  0      
  5  6  1  0      
  6  7  1  0      
  1  8  2  0      
  1  9  1  0      
  6 10  1  0      
 11 12  1  0      
 12 13  1  1      
 11 14  2  0      
 16 17  1  0      
 17 18  1  6      
 18 19  1  0      
 19 20  1  0      
 16 21  2  0      
 19 22  1  0      
 23 24  1  0      
 24 25  1  0      
 23 25  1  0      
 26 27  1  0      
 24 26  1  6      
 16 24  1  0      
 15 17  1  0      
 11 15  1  0      
 13 28  1  0      
  9 12  1  0      
M  END
>  <Catalog Number> (1)
A8172

>  <Item Name> (1)
Dihydroeponemycin

>  <Formula> (1)
C20H36N2O6

>  <MolWeight> (1)
400.51

>  <CAS Number> (1)
126463-64-7

>  <Target> (1)
Proteasome

>  <URL> (1)
http://www.apexbt.com/search.php?catalog=A8172

$$$$

Untitled Document
  ChemDraw02281419052D
 35 35  0  0  0  0  0  0  0  0999 V2000
   -3.0661    2.9782    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.5219    2.5476    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.3769    1.9376    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.7761    1.7582    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.3203    2.1888    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.4653    2.7988    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.7195    2.0094    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.5745    1.3994    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.9737    1.2200    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.8287    0.6100    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
   -0.5179    1.6506    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.2279    0.4306    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.0828   -0.1794    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.5179   -0.3588    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
   -0.5386   -0.6100    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.2279    0.8612    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.8287    0.6818    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.2844    1.1124    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.9737    0.0718    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.6630   -0.9688    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.2638   -1.1482    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.2072   -1.3994    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.3523   -2.0094    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.9531   -2.1888    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.1035   -2.4400    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4088   -1.7582    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
    1.7195   -0.7176    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.0096   -1.9376    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.1546   -2.5476    0.0000 B   0  0  0  0  0  0  0  0  0  0  0  0
    2.7554   -2.7270    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.6989   -2.9782    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.4653   -1.5070    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.0661   -1.6864    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.5219   -1.2558    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.2112   -2.2963    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  2  0      
  2  3  1  0      
  3  4  2  0      
  4  5  1  0      
  5  6  2  0      
  6  1  1  0      
  5  7  1  0      
  7  8  1  0      
  8  9  1  0      
  9 10  1  0      
  9 11  2  0      
 10 12  1  0      
 12 13  1  0      
 13 14  1  0      
 13 15  2  0      
 12 16  1  1      
 16 17  1  0      
 17 18  1  0      
 17 19  1  0      
 14 20  1  0      
 20 21  1  0      
 20 22  1  6      
 22 23  1  0      
 23 24  1  0      
 23 25  1  0      
 21 26  1  0      
 21 27  2  0      
 26 28  1  0      
 28 29  1  0      
 29 30  1  0      
 29 31  1  0      
 28 32  1  1      
 32 33  1  0      
 33 34  1  0      
 33 35  1  0      
M  END
>  <Catalog Number> (1)
A8179

>  <Item Name> (1)
MG-262

>  <Formula> (1)
C25H42BN3O6

>  <MolWeight> (1)
491.44

>  <CAS Number> (1)
N/A

>  <Target> (1)
Proteasome

>  <URL> (1)
http://www.apexbt.com/search.php?catalog=A8179

$$$$

