Search results for: 'CIAP1/2'
- GDC-0152Catalog No. :A4224IAP antagonist,potent amd samll-molecule
GDC-0152 is a potent small-molecule antagonist of inhibitor of apoptosis (IAP) proteins, including ML-IAP, XIAP, cIAP1 and cIAP2, that binds to the BIR domain of ML-IAP and the BIR3 domains of XIAP, cIAP1 and cIAP2 with values of inhibition constant Ki of 14 nM, 28 nM, 17 nM and 43 nM respectively.
- Birinapant (TL32711)Catalog No. :A4219Potent XIAP/cIAP1 antagonist
Birinapant, also called TL32711, is a potent antagonist for XIAP with Kd value of 45 nM and cIAP1 with Kd value <1 nM .