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Mitochondrial Permeability Transition Pore Assay Kit

Catalog No.
K2061
Distinguishes between apoptotic & healthy cells
Grouped product items
SizePriceStock Qty
100 assays
$510.00
In stock

Tel: +1-832-696-8203

Email: [email protected]

Worldwide Distributors

Background

Mitochondria is the cell power centrals and have a significant role in the energy production. Apoptosis is induced upon damages of mitochondria.

MPT pore or MPTP (mitochondrial permeability transition pore) is a nonspecific channel. It formed by inner and out mitochondrial membranes components and mediates in the releases of mitochondrial components in cell death. MPTP’s switch between open and closed states in healthy cells, but during cell death, it significantly change the mitochondria permeability. Cytochrome c release and loss of mitochondrial membrane potential are subsequent to continuous pore activation. Mitochondrial Permeability Transition Pore Assay Kit gives a direct method of measuring cell death by measuring MPTP opening rather than relying on mitochondrial membrane potential alone.

Features & Properties

FeaturesSimple procedure. Fast, convenient and sensitive. The assay provides a direct method of measuring mitochondrial permeability transition pore activation as an early marker of apoptosis.
ShippingGel pack
Storage ConditionsStore at -20°C.

Quality Control

Quality Control & DataSheet

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Related Biological Data

Mitochondrial Permeability Transition Pore Assay Kit
 

Storage

Store at -20°C.

Overview

Kit componentsMPTP Staining Dye CoCl2 Ionomycin MPTP Wash Buffer