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IGF-1, human recombinant

In stock
Catalog No.
P1016
IGF-1, endocrine hormone, expressed in E.Coli, cross-species reactivity.
Grouped product items
SizePriceStock Qty
20ug
$180.00
In stock
100ug
$615.00
In stock

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Background

Insulin-like growth factor I (IGF-1) is a polypeptide endocrine hormone structurally similar to insulin and is mainly produced in the liver when stimulated by growth hormone. IGF-1 is a growth factor that stimulates the proliferation of various cell types including muscle, bone, and cartilage tissue. IGF-1 binds and interacts with the IGF-1 binding proteins (IGFBPs). IGF-1 binds to the IGF-1 receptor with a higher affinity than the insulin receptor.

 Human IGF-I is synthesized as two precursor isoforms with N- and alternate C-terminal propeptides, which are proteolyzed to produce the identical 7.6 kDa mature IGF-I. Mature human IGF I shares 94% and 96% aa sequence identity with mouse IGF1 and rat IGF1, respectively, and exhibits cross species activity. Human IGF-1 is a 7.6 kDa protein containing 70 amino acid residues. The recombinant human IGF-1 was produced using animal origin free technology.

Biological Activity

Determined using dose dependent stimulation of Balbc 3T3 cell line.
ED50 21.6-54.7 ng/ml.          

Quality Control

Quality Control & DataSheet

View current batch:
    Purity: ≥98%, by SDS-PAGE and HPLC.
    Endotoxin Level:<0.1 ng/μg

Related Biological Data

IGF-1

Related Biological Data

IGF-1

Related Biological Data

IGF-1
 

Description

Gene ID: 3479 Accession #: P05019
Alternate Names:IGF1A, Insulin-Like Growth Factor 1, Somatomedin C, IGF-I, IGFI, IGF1, IGF-IA, Mechano growth factor, MGF.
Source: Escherichia Coli. M.Wt: 7.6 kDa
Appearance: Lyophilized powder Storage: Store at -20°C
Formulation:Lyophilized with no additives.
Solubility:Reconstitute in water to a concentration of 0.1-1.0 mg/ml. This solution can then be diluted into other aqueous buffers and stored at 4℃ for 1 week or -20℃ for future use.
Shipping Condition: Gel pack. Handling: Centrifuge the vial prior to opening.
Usage:For Research Use Only! Not to be used in humans.