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Caspase-8, human recombinant protein

Catalog No.
E1008
Caspase-8, expressed in E. coli, suitable for cell culture.
Grouped product items
SizePriceStock Qty
25 units
$221.00
Ship with 10-15 days
100 units
$384.00
Ship with 10-15 days

Tel: +1-832-696-8203

Email: [email protected]

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Background

Caspase-8 (also called FLICE, MASH, Mch5) belongs to the caspase-family of cysteine proteases. Caspase-8 like other caspases also exists in cells as an inactive proenzyme. Sequential activation of caspases plays a key role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymescomposed of a prodomain, a large and a small protease subunit. The N-terminal FADD-like death effector domain of this protein suggests that it may interact with Fas-interacting protein FADD. Active caspase-8 has been demonstrated to activate caspase-3 leading to degradation of a various of cellular target proteins during apoptosis. The recombinant active human caspase-8 was expressed in E. coli.

Description

Gene ID: 841 Accession #: Q14790
Alternate Names:Active Human Caspase-8, Active Caspase-8, Caspase-8 Enzyme, Recombinant caspase-8, human caspase-8, human caspases, active caspases.
Source: Escherichia Coli. M.Wt: N/A
Appearance: Lyophilized powder Storage: Store at -70℃
Formulation:Lyophilized powder
Solubility:Reconstitute to 1 unit per μl in PBS containing 15% glycerol.
Shipping Condition: Gel pack. Handling: Centrifuge the vial prior to opening.
Usage:For Research Use Only! Not to be used in humans.

Quality Control

Quality Control & DataSheet

View current batch:
    Purity: ≥95%, by SDS-PAGE.
    Endotoxin Level:N/A