Search results for: 'research-area stem-cell hippo-signaling'
- CHIR-99021 (CT99021)Catalog No. :A3011GSK-3 inhibitor, Cell-permeable, ATP-competitive
CHIR-99021 is a highly specific glycogen synthase kinase-3 (GSK-3) inhibitor which can inhibit both isoforms with IC50 of 10 nM (GSK-3α) and 6.7 nM (GSK-3β).
- CHIR-99021 (CT99021) HClCatalog No. :A8396GSK-3α/β inhibitorCHIR-99021 is a highly specific glycogen synthase kinase-3 (GSK-3) inhibitor which can inhibit both isoforms with IC50 of 10 nM (GSK-3α) and 6.7 nM (GSK-3β).
- LY2090314Catalog No. :A3570Potent GSK-3 inhibitorLY2090314 is a potent inhibitor of glycogen synthase kinase-3 (GSK-3) which plays an important role in many pathways, including initiation of protein synthesis, cell proliferation, cell differentiation, and apoptosis.
- BikininCatalog No. :B4898GSK3 inhibitor and Brassinosteroid activatorBikini is a strong activator of Brassinosteroid (BR) signaling  and an inhibitor of glycogen synthase kinase 3 proteins (GSK3) .
- A-674563Catalog No. :A8616Akt1/PKA/CDK2 inhibitor,potent and selectiveA-674563 is a potent selective protein kinase B/Akt inhibitor with an IC50 of 14 nM.
- SB 216763Catalog No. :A8240GSK-3 inhibitor,ATP-competitive,potent and selective
SB-216763 is a Potent and selective inhibitor of glycogen synthase kinase-3 (GSK-3) with IC50 of 34.3 nM.
- AR-A014418Catalog No. :A3184GSK3β inhibitor, ATP-competitive and selective
AR-A014418 is a effective GSK3 inhibitor with an IC 50 value of 104 +/- 27 nM.
- CHIR-124Catalog No. :A8394Chk1 inhibitor,novel and potentCHIR-124, a selective inhibitor, inhibits Chk1 with IC50 value of 0.3nM 2,000-fold more potently than Chk2 with IC50 value of 0.7μM. CHIR-124 also potently targets other kinases such as PDGFR with IC50 value of 6.6nM and FLT3 with IC50 value of 5.8nM .