Search results for: 'research-area stem-cell hippo-signaling'
- STF-62247Catalog No. :B2151Autophagy inducer in renal cellSTF-62247 shows selectivtoxicity and growth inhibition of renal cells lacking VHL; 25-fold greater sensitivity observed for cells with VHL deficiency compared to wild-type (VHL+).
- Chloroquine diphosphateCatalog No. :A8628Antimalarial drug,TLR7 TLR9 inhibitor
Chloroquine diphosphate is used as an antimalarial drug and also functions to increase sensitivity of tumor cells to radiation and chemotherapy via inducing autophagy .
- Tenovin-1Catalog No. :A4203SIRT2 inhibitor, activates p53Tenovin-1, a small molecule discovered by a cell-based screen, is a bio-active activator of p53 that elevates the levels of p53 protein, p53-downstream target p21CIP/WAF1 protein and mRNA and protects p53 from mdm2-mediated degradation with little impact on p53 synthesis.