Search results for: 'research-area stem-cell hippo-signaling'
- STF-62247Catalog No. :B2151Autophagy inducer in renal cellSTF-62247 shows selectivtoxicity and growth inhibition of renal cells lacking VHL; 25-fold greater sensitivity observed for cells with VHL deficiency compared to wild-type (VHL+).
- Chloroquine diphosphateCatalog No. :A8628Antimalarial drug,TLR7 TLR9 inhibitor
Chloroquine diphosphate is used as an antimalarial drug and also functions to increase sensitivity of tumor cells to radiation and chemotherapy via inducing autophagy .
- ZM 447439Catalog No. :A4113Aurora Kinase inhibitor,potent and selective
ZM 447439 is a novel, potent and selective inhibitor of Aurora kinase, a family of serine/threonine kinases essential for accurate chromosome segregation during cell division, that inhibits the activity of purified recombinant Aurora A and Aurora B proteins in vitro with 50% inhibition concentration IC50 values of 110 nM and 130 nM respectively and hence inhibits phosphorylation of histone H3 on serine 10.