Search results for: 'research-area stem-cell hippo-signaling'
- SB 203580Catalog No. :A8254P38 MAP kinase inhibitor
SB203580, also called 4-(4-fluorophenyl)-2-(4-methylsulfinylphenyl)-5-(4-pyridyl) 1Himidazole , is a specific pyridinyl imidazole inhibitor of p38-MAPK (Mitogen-activated Protein Kinase) signaling pathway  .
- TAK-242Catalog No. :A3850TLR 4 signaling inhibitor
IC50: With IC50 of 1.1 to 11 nM, TAK-242 inhibited LPS-induced NO production, tumor necrosis factor-alpha and interleukin (IL)-6 in RAW264.7 cells and mouse peritoneal macrophages .
- AMG232Catalog No. :A8804p53-MDM2 inhibitor, novel
A potent and selective piperidinone inhibitor of the MDM2–p53 interaction.
- ImiquimodCatalog No. :A5161TLR-7 agonist,immunomodulator with antiviral and antitumor activityIC50: Imiquimod activates toll-like receptor 7 (EC50 2.1 μM) on immune cells and also enables an OGF-mediated block of cell proliferation (IC50 2 μM) .