Search results for: 'research-area stem-cell hippo-signaling'
- TAK-242Catalog No. :A3850TLR 4 signaling inhibitor
IC50: With IC50 of 1.1 to 11 nM, TAK-242 inhibited LPS-induced NO production, tumor necrosis factor-alpha and interleukin (IL)-6 in RAW264.7 cells and mouse peritoneal macrophages .
- ImiquimodCatalog No. :A5161TLR-7 agonist,immunomodulator with antiviral and antitumor activityIC50: Imiquimod activates toll-like receptor 7 (EC50 2.1 μM) on immune cells and also enables an OGF-mediated block of cell proliferation (IC50 2 μM) .
- LRRK2-IN-1Catalog No. :A3558LRRK2 inhibitor,cell-permeable and ATP competitive
LRRK2-IN-1 is a potent and selective inhibitor of LRRK2 with IC50 value of 13 nM.
- AT-101Catalog No. :A3196BH3-mimetic,gossypol enantiomerAT101, a natural product from cottonseed with a BH3-mimetic structure, was identified as a small molecule inhibitor of Bcl-2/Bcl-xL/Mcl-1 that potently induces apoptosis in various cancer cell lines .