Search results for: 'research-area stem-cell hippo-signaling'
- TAK-242Catalog No. :A3850TLR 4 signaling inhibitor
IC50: With IC50 of 1.1 to 11 nM, TAK-242 inhibited LPS-induced NO production, tumor necrosis factor-alpha and interleukin (IL)-6 in RAW264.7 cells and mouse peritoneal macrophages .
- ImiquimodCatalog No. :A5161TLR-7 agonist,immunomodulator with antiviral and antitumor activityIC50: Imiquimod activates toll-like receptor 7 (EC50 2.1 μM) on immune cells and also enables an OGF-mediated block of cell proliferation (IC50 2 μM) .
- PhloretinCatalog No. :A3723A dihydrochalcone found in apple
Phloretin is a dihydrochalcone, a type of natural phenols. It can be found in apple tree leaves. Phloretin inhibits the active transport of glucose into cells by SGLT1 and SGLT2. Phloretin can block other glucose transporter including GLUT1.