Search results for: 'research-area stem-cell hippo-signaling'
- ThiazovivinCatalog No. :A5506ROCK inhibitorGreatly enhances the efficiency of fibroblast reprogramming to generate induced pluripotent stem cells (iPSCs) when used in combination with SB 431542 and PD 0325901.
- SR-3677Catalog No. :B1294Rho Kinase (ROCK-II) inhibitorSR-3677 is a novel, potent and highly selective inhibitor of Rho Kinase (ROCK-II) with the IC50 value of ~0.3nM in enzyme and cell based assays .
- Fasudil (HA-1077) HClCatalog No. :A5734Protein kinase inhibitorCyclic nucleotide-dependent protein kinase inhibitor and Rho-associated kinase inhibitor (IC50 = 10.7 μM).
- GSK429286ACatalog No. :A5611Selective ROCK1/ROCK2 inhibitorSelective Rho-kinase inhibitor (IC50 values are 14, 780 and 1940 nM for ROCK1, RSK and p70S6K respectively).
- SLx-2119Catalog No. :A3825Selective ROCK2 inhibitor
SLx-2119(KD-025) is a selective inhibitor of ROCK2 with IC50 of 105 nM .
- RKI-1447Catalog No. :A3771Potent ROCK1/ROCK2 inhibitorRKI-1447 is a potent small molecule inhibitor of ROCK1 and ROCK2.
- Y-27632 dihydrochlorideCatalog No. :A3008ROCK1 inhibitor
Y-27632 dihydrochloride is a small-molecule inhibitor of Rho-associated protein kinase p160ROCK with the IC50 of 140 nM.