Search results for: 'research-area stem-cell hippo-signaling'
- Epothilone B (EPO906, Patupilone)Catalog No. :A1630Microtubule stabilizing macrolideEpothilone B (EPO906, Patupilone) is a naturally occurring microtubule-stabilizing macrolide that was first isolated from the myxobacterium Sorangium cellulosum. The EC0.01 value of Epothilone B is 1.8 nM .
- Paclitaxel (Taxol)Catalog No. :A4393Antineoplastic agent
Paclitaxel is a novel antineoplastic agent, which was discovered in a screen of extracts of thousands of plants and natural products for antineoplastic activity by a National Cancer Institute program.
- NocodazoleCatalog No. :A8487Tubulin production inhibitor,anti-neoplastic agent
Nocodazole is a reversible anti-neoplastic agent which exerts its effect in cells by interfering with the polymerization of microtubules (tubulin).
- Ansamitocin P-3Catalog No. :A3183Inhibitor of tublin spiralization,maytansine analogAnsamitocin P-3, a natural product, is maytansinoid which showed potent cytotoxicity against the human solid tumor cell lines A-549 and HT-29 with ED50 of 4 x 10 -7, 4 x 10 – 7 μg/ml, respectively.