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  • Search results for: 'research-area stem-cell hippo-signaling'

Search results for: 'research-area stem-cell hippo-signaling'

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Items 1-10 of 11

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  1. CHIR-99021 (CT99021)
    A3011 CHIR-99021 (CT99021)
     2 Citation
    Target: GSK-3
    Summary: GSK-3 inhibitor, Cell-permeable, ATP-competitive
      ≥23.3 mg/mL
  2. CHIR-99021 (CT99021) HCl
    A8396 CHIR-99021 (CT99021) HCl
    Target: GSK-3
    Summary: GSK-3α/β inhibitor
      ≥25.1 mg/mL
  3. LY2090314
    A3570 LY2090314
    Target: GSK-3
    Summary: Potent GSK-3 inhibitor
      ≥91 mg/mL
      ≥4.27 mg/mL
      insoluble in h2o
  4. A-674563
    A8616 A-674563
    Target: Cyclin-Dependent Kinases|Akt|GSK-3|ERK|PKC|PKA|RSK
    Summary: Akt1/PKA/CDK2 inhibitor,potent and selective
      ≥4.9 mg/mL
  5. SB 216763
    A8240 SB 216763
     3 Citation
    Target: GSK-3
    Summary: GSK-3 inhibitor,ATP-competitive,potent and selective
      ≥56.8 mg/mL
      insoluble in etoh
      insoluble in h2o
  6. SB-505124 hydrochloride
    A3799 SB-505124 hydrochloride
    Target: ALK
    Summary: ALK5/ALK4/ALK7 inhibitor in TGF-β/activin signalling,selective
      ≥9.3 mg/mL
      ≥87 mg/mL
      insoluble in h2o
  7. AR-A014418
    A3184 AR-A014418
     2 Citation
    Target: GSK-3
    Summary: GSK3β inhibitor, ATP-competitive and selective
      ≥15.4 mg/mL
      insoluble in etoh
      insoluble in h2o
  8. CHIR-124
    A8394 CHIR-124
    Target: FLT3|GSK-3|Chk|PDGFR
    Summary: Chk1 inhibitor,novel and potent
      ≥10.5 mg/mL
  9. CEP-37440
    B3271 CEP-37440
    Target: FAK|ALK
    Summary: FAK/ALK inhibitor,potent and selective
      ≥9.25 mg/mL
  10. GSK1838705A
    A8440 GSK1838705A
    Target: Insulin and Insulin-like Receptors|ALK
    Summary: IGF-IR/IR/ALK inhibitor, ATP-competitive
      ≥26.65 mg/mL

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  1. Target ALK Remove This Item
  2. Target GSK-3 Remove This Item
  3. Reported Experiments Animal Experiments Remove This Item
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Category
Specificity
  1. Selective 6 items
Reversibility
  1. Reversible 1 item
Target
  1. Caspases 5 items
  2. Cyclin-Dependent Kinases 15 items
  3. Proteasome 5 items
  4. Cathepsins 1 item
  5. Histone Deacetylases (HDACs) 14 items
  6. Inhibitor of apoptosis proteins (IAP) 1 item
  7. Akt 9 items
  8. Bcl-2 2 items
  9. PI3K 15 items
  10. Raf 9 items
  11. Aurora Kinases 3 items
  12. Glycoproteins 1 item
  13. MDM2 1 item
  14. EZH2 1 item
  15. mTOR 8 items
  16. AP-1 2 items
  17. MMP 1 item
  18. Androgen Receptors 1 item
  19. Myosin II ATPases 1 item
  20. FLT3 2 items
  21. GSK-3 7 items
  22. LPA Receptors 1 item
  23. P-glycoprotein (P-gp) 3 items
  24. PLK 7 items
  25. Chk 4 items
  26. VEGFR 7 items
  27. PDGFR 4 items
  28. c-Kit 1 item
  29. Bromodomain-containing proteins(BRDs) 1 item
  30. Phosphodiesterases (PDEs) 2 items
  31. Hydrolase 1 item
  32. p38 4 items
  33. PKB 1 item
  34. JNK 2 items
  35. MEK 5 items
  36. PORCN 1 item
  37. DOT1L 1 item
  38. FGFR 3 items
  39. Glucagon-like peptide 1 (GLP-1) receptors 1 item
  40. Sir2-like Family Deacetylases (Sirtuins) 1 item
  41. Smoothened 2 items
  42. Ras 1 item
  43. Trk Receptors 1 item
  44. STAT 7 items
  45. Microtubules/Tubulins 4 items
  46. Estrogen and Related Receptors 1 item
  47. EGFR 6 items
  48. Hedgehog 1 item
  49. ROCK 5 items
  50. FAK 4 items
  51. BMP and Other Activin Receptors 2 items
  52. JAK 5 items
  53. p300 1 item
  54. Stearoyl-CoA 9-desaturase (SCD-1) 1 item
  55. Syk 1 item
  56. DNA-PK 2 items
  57. HSP90 1 item
  58. AMPK 2 items
  59. CCR 1 item
  60. CFTR 3 items
  61. TNKS 1 item
  62. Cytochrome P450 (CYP450) 1 item
  63. ErbB 2 items
  64. Toll-like receptors (TLRs) 2 items
  65. Actin 1 item
  66. DNA Methyltransferases 1 item
  67. Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitors (HIF-PHIs) 1 item
  68. ERK 3 items
  69. BMI-1 1 item
  70. PKC 10 items
  71. Ca2 /calmodulin-dependent protein kinases (CaMKs) 1 item
  72. Lyn 1 item
  73. SGLT 1 item
  74. RAD51 1 item
  75. Pyk2 3 items
  76. LRRK2 2 items
  77. Voltage-gated Calcium Channels (CaV) 1 item
  78. Insulin and Insulin-like Receptors 1 item
  79. ALK 4 items
  80. Sphingosine kinases (SphKs) 1 item
  81. PKG 1 item
  82. PKA 5 items
  83. D2 Receptors 1 item
  84. Fatty-acid-binding proteins (FABPs) 1 item
  85. Tie-2 1 item
  86. RSK 1 item
  87. Free Fatty Acid Receptors 1 item
  88. phosphatases 1 item
  89. Autophagy 2 items
  90. ATM/ATR 2 items
  91. Farnesyl Diphosphate Synthases 1 item
  92. HIV Integrases 1 item
  93. Melatonin Receptors 1 item
  94. Peroxynitrite 1 item
  95. MAGL 1 item
  96. NPY Receptors 1 item
  97. Histamine H1 Receptors 3 items
  98. TRP Channel 1 item
  99. MNK 1 item
  100. NO Donors / Precursors 1 item
  101. Glucocorticoid Receptors 1 item
  102. IL Receptors 1 item
  103. 15-lipoxygenases 1 item
  104. Inward Rectifier Potassium (Kir) Channels 2 items
  105. O6-methylguanine-DNA-methyl-transferase (MGMT) 1 item
  106. NMDA receptor 1 item
  107. Aldosterone receptor 1 item
  108. RNA synthesis 1 item
  109. BACE 1 item
  110. DPP-4 1 item
  111. DREADD Ligands 1 item
  112. p70 rsk 2 items
  113. Microtubule/Tubulin 2 items
  114. p53-MDM2 interaction 1 item
  115. KDR 1 item
  116. p53 3 items
  117. c-Fms tyrosine kinase 1 item
  118. insulin 1 item
  119. Ub-conjugating enzyme (E2) complex 1 item
  120. Smoothened receptor 1 item
  121. PPAR 1 item
  122. HDM2 ubiquitin ligase 1 item
  123. Glucosidases 1 item
  124. Vitamin D receptors (VDRs) 1 item
  125. Antibiotic 1 item
  126. DNA Alkylating 1 item
  127. GLI 1 item
  128. Stem Cell Differentiation 1 item
  129. PP2A/Nkd interaction 1 item
  130. adrenergic receptor 1 item
  131. Prk 1 item
  132. Ribonucleotide Reductases 1 item
  133. Rho 1 item
  134. Aryl hydrocarbon receptors (AHRs) 1 item
  135. DCLK2 1 item
  136. phosphatidylinositol kinase 1 item
  137. Adenosine Deaminases 1 item
  138. Histamine receptors 1 item
  139. GluR 1 item
  140. 5-HT receptor 1 item
  141. dopamine receptors 1 item
  142. AMPA receptor 1 item
  143. Flk1 1 item
  144. p21 1 item
  145. RHA 1 item
  146. TRPC channel 1 item
  147. FKBP 1 item
  148. Bcl-w 1 item
  149. PPK 1 item
  150. c-Syk 1 item
  151. CDK1/CyclinB 1 item
  152. FXR 1 item
  153. Vascular Disrupting Agents (VDA) 1 item
  154. Sirtuin 1 item
  155. PIKfyve 1 item
  156. Bax 1 item
  157. NS3/4a Proteases 1 item
  158. p90 S6K 1 item
Related Disease
  1. Cancer 7 items
  2. Leukemia 1 item
  3. Melanoma 1 item
  4. Neuroblastoma 1 item
  5. Pancreatic Cancer 1 item
  6. Type 2 Diabetes 1 item