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  • Search results for: 'research-area stem-cell hippo-signaling'

Search results for: 'research-area stem-cell hippo-signaling'

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Items 1-10 of 11

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  1. CHIR-99021 (CT99021)
    A3011 CHIR-99021 (CT99021)
     2 Citation
    Target: GSK-3
    Summary: GSK-3 inhibitor, Cell-permeable, ATP-competitive
      ≥23.3 mg/mL
  2. CHIR-99021 (CT99021) HCl
    A8396 CHIR-99021 (CT99021) HCl
    Target: GSK-3
    Summary: GSK-3α/β inhibitor
      ≥25.1 mg/mL
  3. LY2090314
    A3570 LY2090314
    Target: GSK-3
    Summary: Potent GSK-3 inhibitor
      ≥91 mg/mL
      ≥4.27 mg/mL
      <2.63 mg/mL
  4. A-674563
    A8616 A-674563
    Target: Cyclin-Dependent Kinases|Akt|GSK-3|ERK|PKC|PKA|RSK
    Summary: Akt1/PKA/CDK2 inhibitor,potent and selective
      ≥4.9 mg/mL
  5. SB 216763
    A8240 SB 216763
     3 Citation
    Target: GSK-3
    Summary: GSK-3 inhibitor,ATP-competitive,potent and selective
      ≥56.8 mg/mL
      <2.38 mg/mL
      <2.62 mg/mL
  6. SB-505124 hydrochloride
    A3799 SB-505124 hydrochloride
    Target: ALK
    Summary: ALK5/ALK4/ALK7 inhibitor in TGF-β/activin signalling,selective
      ≥9.3 mg/mL
      ≥87 mg/mL
      <2.18 mg/mL
  7. AR-A014418
    A3184 AR-A014418
     2 Citation
    Target: GSK-3
    Summary: GSK3β inhibitor, ATP-competitive and selective
      ≥15.4 mg/mL
      <2.19 mg/mL
      <2.7 mg/mL
  8. CHIR-124
    A8394 CHIR-124
    Target: FLT3|GSK-3|Chk|PDGFR
    Summary: Chk1 inhibitor,novel and potent
      ≥10.5 mg/mL
  9. CEP-37440
    B3271 CEP-37440
    Target: FAK|ALK
    Summary: FAK/ALK inhibitor,potent and selective
      ≥9.25 mg/mL
  10. GSK1838705A
    A8440 GSK1838705A
    Target: Insulin and Insulin-like Receptors|ALK
    Summary: IGF-IR/IR/ALK inhibitor, ATP-competitive
      ≥26.65 mg/mL

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  2. Target GSK-3 Remove This Item
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Category
Specificity
  1. Selective 6 items
Reversibility
  1. Reversible 1 item
Target
  1. Caspases 5 items
  2. Cyclin-Dependent Kinases 15 items
  3. Proteasome 5 items
  4. Cathepsins 1 item
  5. Histone Deacetylases (HDACs) 14 items
  6. Inhibitor of apoptosis proteins (IAP) 1 item
  7. Akt 9 items
  8. Bcl-2 2 items
  9. PI3K 15 items
  10. Raf 9 items
  11. Aurora Kinases 3 items
  12. Glycoproteins 1 item
  13. MDM2 1 item
  14. EZH2 1 item
  15. mTOR 8 items
  16. AP-1 2 items
  17. MMP 2 items
  18. Androgen Receptors 1 item
  19. Myosin II ATPases 1 item
  20. FLT3 2 items
  21. GSK-3 7 items
  22. LPA Receptors 1 item
  23. P-glycoprotein (P-gp) 3 items
  24. PLK 7 items
  25. Chk 4 items
  26. VEGFR 7 items
  27. PDGFR 4 items
  28. c-Kit 1 item
  29. Bromodomain-containing proteins(BRDs) 1 item
  30. Phosphodiesterases (PDEs) 2 items
  31. Hydrolase 1 item
  32. p38 4 items
  33. PKB 1 item
  34. JNK 2 items
  35. MEK 5 items
  36. PORCN 1 item
  37. DOT1L 1 item
  38. FGFR 3 items
  39. Glucagon-like peptide 1 (GLP-1) receptors 1 item
  40. Sir2-like Family Deacetylases (Sirtuins) 1 item
  41. Smoothened 2 items
  42. Ras 1 item
  43. Trk Receptors 1 item
  44. STAT 7 items
  45. Microtubules/Tubulins 4 items
  46. Estrogen and Related Receptors 1 item
  47. EGFR 6 items
  48. Hedgehog 1 item
  49. ROCK 5 items
  50. FAK 4 items
  51. BMP and Other Activin Receptors 2 items
  52. JAK 5 items
  53. p300 1 item
  54. Stearoyl-CoA 9-desaturase (SCD-1) 1 item
  55. Syk 1 item
  56. DNA-PK 2 items
  57. HSP90 1 item
  58. AMPK 2 items
  59. CCR 1 item
  60. CFTR 3 items
  61. TNKS 1 item
  62. Cytochrome P450 (CYP450) 1 item
  63. ErbB 2 items
  64. Toll-like receptors (TLRs) 2 items
  65. DNA Methyltransferases 1 item
  66. Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitors (HIF-PHIs) 1 item
  67. ERK 3 items
  68. BMI-1 1 item
  69. PKC 10 items
  70. Ca2 /calmodulin-dependent protein kinases (CaMKs) 1 item
  71. Lyn 1 item
  72. SGLT 1 item
  73. RAD51 1 item
  74. Pyk2 3 items
  75. LRRK2 2 items
  76. Voltage-gated Calcium Channels (CaV) 1 item
  77. Insulin and Insulin-like Receptors 1 item
  78. ALK 4 items
  79. Sphingosine kinases (SphKs) 1 item
  80. PKG 1 item
  81. PKA 5 items
  82. Fatty-acid-binding proteins (FABPs) 1 item
  83. Tie-2 1 item
  84. RSK 1 item
  85. Free Fatty Acid Receptors 1 item
  86. phosphatases 1 item
  87. Autophagy 2 items
  88. ATM/ATR 2 items
  89. Farnesyl Diphosphate Synthases 1 item
  90. HIV Integrases 1 item
  91. Melatonin Receptors 1 item
  92. Peroxynitrite 1 item
  93. MAGL 1 item
  94. NPY Receptors 1 item
  95. Histamine H1 Receptors 2 items
  96. TRP Channel 1 item
  97. MNK 1 item
  98. NO Donors / Precursors 1 item
  99. Glucocorticoid Receptors 1 item
  100. IL Receptors 1 item
  101. 15-lipoxygenases 1 item
  102. Inward Rectifier Potassium (Kir) Channels 2 items
  103. O6-methylguanine-DNA-methyl-transferase (MGMT) 1 item
  104. NMDA receptor 1 item
  105. Aldosterone receptor 1 item
  106. RNA synthesis 1 item
  107. BACE 1 item
  108. DPP-4 1 item
  109. DREADD Ligands 1 item
  110. p70 rsk 2 items
  111. Microtubule/Tubulin 2 items
  112. p53-MDM2 interaction 1 item
  113. KDR 1 item
  114. p53 3 items
  115. c-Fms tyrosine kinase 1 item
  116. insulin 1 item
  117. Ub-conjugating enzyme (E2) complex 1 item
  118. Smoothened receptor 1 item
  119. PPAR 1 item
  120. HDM2 ubiquitin ligase 1 item
  121. Glucosidases 1 item
  122. Vitamin D receptors (VDRs) 1 item
  123. Antibiotic 1 item
  124. DNA Alkylating 1 item
  125. GLI 1 item
  126. Stem Cell Differentiation 1 item
  127. PP2A/Nkd interaction 1 item
  128. adrenergic receptor 1 item
  129. Prk 1 item
  130. Ribonucleotide Reductases 1 item
  131. Rho 1 item
  132. Aryl hydrocarbon receptors (AHRs) 1 item
  133. DCLK2 1 item
  134. phosphatidylinositol kinase 1 item
  135. Adenosine Deaminases 1 item
  136. Histamine receptors 1 item
  137. GluR 1 item
  138. 5-HT receptor 1 item
  139. dopamine receptors 1 item
  140. AMPA receptor 1 item
  141. Flk1 1 item
  142. p21 1 item
  143. RHA 1 item
  144. FKBP 1 item
  145. Bcl-w 1 item
  146. PPK 1 item
  147. c-Syk 1 item
  148. CDK1/CyclinB 1 item
  149. FXR 1 item
  150. Vascular Disrupting Agents (VDA) 1 item
  151. Sirtuin 1 item
  152. PIKfyve 1 item
  153. Bax 1 item
  154. NS3/4a Proteases 1 item
  155. p90 S6K 1 item
Related Disease
  1. Cancer 7 items
  2. Leukemia 1 item
  3. Melanoma 1 item
  4. Neuroblastoma 1 item
  5. Pancreatic Cancer 1 item
  6. Type 2 Diabetes 1 item