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Search results for: 'research-area stem-cell hippo-signaling'

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Items 1-10 of 38

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  1. LY2090314
    A3570 LY2090314
    Target: GSK-3
    Summary: Potent GSK-3 inhibitor
      ≥91 mg/mL
      ≥4.27 mg/mL
      insoluble in h2o
  2. Dabrafenib Mesylate (GSK-2118436)
    A3347 Dabrafenib Mesylate (GSK-2118436)
    Target: Raf
    Summary: Inhibitor of BRAF(V600) mutants
      ≥30.75 mg/mL
      ≥2.74 mg/mL
      insoluble in h2o
  3. BYL-719
    A8346 BYL-719
     1 Citation
    Target: PI3K
    Summary: Selective PI3Kα inhibitor
      ≥22.1 mg/mL
  4. LY2228820
    A5566 LY2228820
     1 Citation
    Target: p38
    Summary: P38 MAP kinase inhibitor
      ≥30.65 mg/mL
      ≥9.9 mg/mL
      ≥45 mg/mL
  5. AS-605240
    A5176 AS-605240
    Target: PI3K
    Summary: Potent and selective PI 3-Kγ inhibitor
      ≥4.28 mg/mL
      insoluble in etoh
      insoluble in h2o
  6. GDC-0879
    A5071 GDC-0879
     1 Citation
    Target: Raf
    Summary: B-Raf inhibitor,potent and selective
      ≥16.7 mg/mL
      insoluble in etoh
      insoluble in h2o
  7. TAK-632
    A8226 TAK-632
    Target: Raf
    Summary: Pan-RAF inhibitor,potent and selective
      ≥27.75 mg/mL
      ≥2.23 mg/mL
      insoluble in h2o
  8. Trametinib (GSK1120212)
    A3018 Trametinib (GSK1120212)
     7 Citation
    Target: MEK
    Summary: MEK1 and MEK2 inhibitor, potent and selective
      ≥15.38 mg/mL
  9. MK-2206 dihydrochloride
    A3010 MK-2206 dihydrochloride
     21 Citation
    Target: Akt
    Summary: Akt1/2/3 inhibitor
      ≥12.01 mg/mL
  10. GDC-0068 (RG7440)
    A3006 GDC-0068 (RG7440)
    Target: Akt
    Summary: Pan-AKT inhibitor,highly selective
      ≥22.9 mg/mL

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Specificity
  1. Selective 37 items
  2. Non-Selective 1 item
Target
  1. Caspases 1 item
  2. Cyclin-Dependent Kinases 4 items
  3. Histone Deacetylases (HDACs) 2 items
  4. Akt 2 items
  5. PI3K 2 items
  6. Raf 5 items
  7. Glycoproteins 1 item
  8. mTOR 1 item
  9. GSK-3 1 item
  10. LPA Receptors 1 item
  11. P-glycoprotein (P-gp) 1 item
  12. Chk 1 item
  13. VEGFR 1 item
  14. PDGFR 1 item
  15. Phosphodiesterases (PDEs) 1 item
  16. p38 1 item
  17. MEK 2 items
  18. FGFR 1 item
  19. Microtubules/Tubulins 2 items
  20. EGFR 1 item
  21. JAK 1 item
  22. p300 1 item
  23. SGLT 1 item
  24. phosphatases 1 item
  25. ATM/ATR 1 item
  26. O6-methylguanine-DNA-methyl-transferase (MGMT) 1 item
Reported Experiments
  1. Animal Experiments 36 items
  2. Cell Experiments 23 items
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