Search results for: 'research-area stem-cell hippo-signaling'
- AS-605240Catalog No. :A5176Potent and selective PI 3-Kγ inhibitor
AS-605240 is a selective PI3K γ inhibitor with an IC50 of 8 nM. 
- Ascomycin(FK 520)Catalog No. :A3191Macrolide immunosuppressant,FK-520 analogMixed lymphocyte reaction (MLR) has been thought to be the in vitro correlative model for allograft rejection and a representative reaction of interleukin-2 (IL-2) dependent T cell proliferation.
- Apremilast (CC-10004)Catalog No. :A4317PDE4 inhibitorApremilast, also known as CC-10004, is a novel and potent small-molecule inhibitor of phosphodiesterase 4 (PDE4), a key enzyme involved in cyclic adenosine monophosphate (cAMP) degradation and cytokine production of inflammatory cells.
- Tofacitinib (CP-690550) CitrateCatalog No. :A4135Potent JAK inhibitor
Tofacitinib citrate, also known as CP-690550 citrate, is a potent inhibitor of janus kinase 3 (JAK3), a hematopoetic cell-restricted tyrosine kinase involved in signal transduction regulating lymphocyte survival, proliferation, differentiation, and apoptosis.