Search results for: 'research-area stem-cell hippo-signaling'
- STF-62247Catalog No. :B2151Autophagy inducer in renal cellSTF-62247 shows selectivtoxicity and growth inhibition of renal cells lacking VHL; 25-fold greater sensitivity observed for cells with VHL deficiency compared to wild-type (VHL+).
- Panobinostat (LBH589)Catalog No. :A8178HDAC inhibitor
Panobinostat, as known as LBH589, is a novel and potent hydroxamic acid-based deacetylase inhibitor (DACis)that inhibits a broad spectrum of histone deacetylases (HDACs), including all Classes 1, 2 and 4 HDAC enzymes, at low nanomolar concentrations.
- RO4929097Catalog No. :A4005γ secretase inhibitor
RO4929097 is a small-molecule inhibitor of γ secretase with IC50 of 4 nM and EC50 of 5 nM.