Search results for: 'research-area stem-cell hippo-signaling'
- FludarabineCatalog No. :A5424DNA synthsis inhibitor
Purine analog that inhibits DNA synthesis.
- ASC-J9Catalog No. :A3190AR degradation enhancer,antiumor agentASC-J9, is antitumor agent. ASC-J9 suppresses castration-resistant prostate cancer growth via degradation of full-length and splice variant androgen receptors targeting both fAR- and AR3-mediated PCa growth by ASC-J9 may represent the novel therapeutic approach to suppress castration-resistant PCa.
- Entinostat (MS-275,SNDX-275)Catalog No. :A8171HDAC1 and HDAC3 inhibitorEntinostat (also known as MS-275 or SNDX-275), a derivative of 2-aminophenyl benzamides, is a potent and orally-available inhibitor of histone deacetylases (HDACs), a family of enzymes associated with a variety of well-characterized cellular oncogenes and tumor suppressors, that potently inhibits class I HDACs, including HDAC1, HDAC3 and HDAC8, with values of 50% inhibition concentration IC50 of 0.368 μM, 0.501 μM and 63.4 μM respectively.