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Search results for: 'research-area stem-cell hippo-signaling'

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 Paper Citing APExBIO Products  Ongoing Clinical Trials  Solubility in DMSO  Solubility in Water  Solubility in Ethanol  Solubility in Dimethyl Formamide
  1. 3-Deazaneplanocin A (DZNep) hydrochloride
    A8182 3-Deazaneplanocin A (DZNep) hydrochloride
     1 Citation
    Target: EZH2
    Summary: SAHH and EZH2 inhibitor
      ≥14.9 mg/mL
      <2.99 mg/mL
      ≥18.32 mg/mL
  2. AS-605240
    A5176 AS-605240
    Target: PI3K
    Summary: Potent and selective PI 3-Kγ inhibitor
      ≥4.28 mg/mL
      <2.45 mg/mL
      <2.43 mg/mL
  3. Sorafenib
    A3009 Sorafenib
     2 Citation
    Target: Raf|VEGFR
    Summary: Raf kinases and tyrosine kinases inhibitor
      ≥23.25 mg/mL
  4. Gefitinib (ZD1839)
    A8219 Gefitinib (ZD1839)
     3 Citation
    Target: EGFR
    Summary: Selective EGFR inhibitor
      ≥22.3 mg/mL
      ≥2.48 mg/mL
      <2.76 mg/mL
  5. Gefitinib hydrochloride
    A3433 Gefitinib hydrochloride
    Target: EGFR
    Summary: Potent EGFR inhibitor
      ≥6.9 mg/mL
      <2.16 mg/mL
      ≥4.28 mg/mL
  6. Phloretin
    A3723 Phloretin
    Target: SGLT
    Summary: A dihydrochalcone found in apple
      ≥105 mg/mL
      ≥87.6 mg/mL
      <2.68 mg/mL
  7. Apremilast (CC-10004)
    A4317 Apremilast (CC-10004)
    Target: Phosphodiesterases (PDEs)
    Summary: PDE4 inhibitor
      ≥23.05 mg/mL
      <2.51 mg/mL
      <2.43 mg/mL
  8. Belinostat (PXD101)
    A4096 Belinostat (PXD101)
     2 Citation
    Target: Histone Deacetylases (HDACs)
    Summary: Hydroxamate-type HDAC inhibitor
      ≥15.92 mg/mL
      ≥44.1 mg/mL
      <2.33 mg/mL
  9. Tofacitinib (CP-690550) Citrate
    A4135 Tofacitinib (CP-690550) Citrate
     2 Citation
    Target: JAK
    Summary: Potent JAK inhibitor
      ≥25.22 mg/mL
      <2.53 mg/mL
      ≥3.4 mg/mL

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