Search results for: 'research-area pi3k-akt-signaling'
- XL147Catalog No. :A5112PI3K inhibitor,selective and reversibleXL147 is a potent and orally active inhibitor that targets Class I PI3Ks with IC50 values in the nanomolar level.
- AR-A014418Catalog No. :A3184GSK3β inhibitor, ATP-competitive and selective
AR-A014418 is a effective GSK3 inhibitor with an IC 50 value of 104 +/- 27 nM.
- SorafenibCatalog No. :A3009Raf kinases and tyrosine kinases inhibitor
Sorafenib is an oral multikinase inhibitor with activity against Raf kinase and several receptor tyrosine kinases, including vascular endothelial growth factor receptor 2 (VEGFR2), platelet-derived growth factor receptor (PDGFR), FLT3, Ret, and c-Kit. sorafenib, inhibits tumor growth and disrupts tumor microvasculature through antiproliferative, antiangiogenic, and/or proapoptotic effects.