Search results for: 'research-area pi3k-akt-signaling'
- BIX 02189Catalog No. :A5801Selective MEK5 inhibitorBIX 02189 is a selective inhibitor of MEK5 with IC50 value of 1.5 nM.
- Trametinib (GSK1120212)Catalog No. :A3018MEK1 and MEK2 inhibitor, potent and selective
Trametinib (also known as GSK1120212 or JTP 74057), originally identified as a p15 inductive compound, is a novel and potent allosteric inhibitor of MEK kinase, which exhibits ATP non-competitive inhibition against MEK1 and MEK2 kinase.