Search results for: 'research-area metabolism'
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A3146 AGI-6780Target: IDH2Summary: IDH2/R140Q mutation inhibitor -
A4383 TolcaponeTarget: Catechol O-Methyltransferase (COMT)Summary: COMT inhibitor -
A4381 FK866 (APO866)1 CitationTarget: NamptSummary: NAMPT inhibitor, non-competitive, highly specific -
A4373 NLG9191 CitationSummary: Potent IDO pathway inhibitor -
A4365 LovastatinTarget: HMG-CoA ReductasesSummary: HMG-CoA reductase inhibitor -
A4358 U-104Target: Carbonic AnhydrasesSummary: CAIX inhibitor -
A4347 Methotrexate2 CitationTarget: Folate AnalogueSummary: Folate antagonist,inhibits DFHR -
A4346 AminophyllineTarget: Phosphodiesterases (PDEs)Summary: Pan-PDE inhibitor -
A4333 CPI-6131 CitationTarget: Pyruvate dehydrogenases (PDH)Summary: PDH/α-KGDH inhibitor -
A4330 IsotretinoinTarget: RARsSummary: Dopamine β-hydroxylase activator