Search results for: 'research-area metabolism transferase'
- BMS 309403Catalog No. :B7794FABP4 inhibitor,potent and selective
Potent and selective adipocyte fatty acid binding protein 4 (aFABP4) inhibitor (Ki values are <2, 250 and 350 nM for aFABP4, mFABP4 and eFABP4 respectively). Decreases fatty acid uptake in adipocytes in vitro and reduces atherosclerotic lesion area in a mouse model of atherosclerosis. Reduces blood glucose levels and increases insulin sensitivity in a mouse model of obesity. Orally active.
- CanagliflozinCatalog No. :A8333SGLT2 inhibitor,potent and selective
Canagliflozin is a novel, potent, and highly selective sodium glucose co-transporter (SGLT) 2 inhibitor . It has been proved that Canagliflozin can increase urine glucose excretion by reducing the renal glucose threshold and by decreasing the filtered glucose re-absorption .
- Pioglitazone HClCatalog No. :A4324PPARγ agonistPioglitazone HCl is a potent and highly selective agonist of PPARγ with IC50 value of 3μM.
- Rosiglitazone maleateCatalog No. :A4302PPARγ agonist,high-affinity and selective,potent insulin sensitizerRosiglitazone maleate is the maleic acid salt form of rosiglitazone, a potent insulin sensitizer, which is used for the treatment of diabetes.