Search results for: 'research-area metabolism transferase'
- Ezatiostat hydrochlorideCatalog No. :B1250GST inhibitor
Ezatiostat hydrochloride(TLK199) is an effective inhibitor of glutathione S-transferase （GST）.
- 5-AzacytidineCatalog No. :A1907DNA methyltransferase inhibitor.
5-Azacytidine (also known as 5-AzaC), a compound belonging to a class of cytosine analogues, is a DNA methyl transferase (DNMT) inhibitor that exerts potent cytotoxicity against multiple myeloma (MM) cells, including MM.1S, MM.1R, RPMI-8266, RPMI-LR5, RPMI-Dox40 and Patient-derived MM, with the half maximal inhibition concentration IC50 values of 1.5 μmol/L, 0.7 μmol/L, 1.1 μmol/L, 2.5 μmol/L, 3.2 μmol/L and 1.5 μmol/L respectively .
- FK866 (APO866)Catalog No. :A4381NAMPT inhibitor,non-competitive, highly specificFK866 is an inhibitor of nicotinamide phosphoribosyltransferase (NMPRTase) with IC50 values ranging between 0.09nM and 27.2nM .
- MethotrexateCatalog No. :A4347Folate antagonist,inhibits DFHR
Methotrexate, a folate antagonist, is a potent anti-inflammatory agent when used weekly in low concentrations, the anti-phlogistic action of which is due to increased adenosine release at inflamed sites.