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Search results for: 'research-area ion-channel'

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5 Items

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  1. Gliclazide
    Gliclazide
    Catalog No. :
    B2195
    Potassium channel inhibitor
    Gliclazide is a sulfonylurea hypoglycemic agent used as an antidiabetic.
  2. Mitiglinide Calcium
    Mitiglinide Calcium
    Catalog No. :
    B2193
    Potassium channel inhibitor
    Mitiglinide is a drug for the treatment of type 2 diabetes. It is a highly selective KATP channel antagonist.
  3. Glibenclamide
    Glibenclamide
    Catalog No. :
    B1296
    Insulin production modulator
    Glibenclamide is a sulfonylurea compound that modulates insulin production. Sulfonylureas bind to ATP-dependent K+ channels in beta cells of the pancreas, depolarizing them and stimulating the release of Ca2+, which in turn stimulates insulin production.
  4. Sotalol hydrochloride
    Sotalol hydrochloride
    Catalog No. :
    B3341
    β-adrenergic receptor antagonist

    Sotalol hydrochloride is a potent and non-selective antagonist of β-adrenergic receptor. Sotalol is also an inhibitor of potassinm channels with the IC50 value of ~1.2mM in HEK cell lines .

  5. Terfenadine
    Terfenadine
    Catalog No. :
    A8534
    Histamine H1-receptor antagonist
    Terfenadine is a histamine H1-receptor antagonist, which blocks HERG and KATP (KIR6) channels.

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  1. Target Inward Rectifier Potassium (Kir) Channels Remove This Item
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Category
Specificity
  1. Selective 3 items
  2. Non-Selective 1 item
Target
  1. Gap Junctions 1 item
  2. Voltage-gated Potassium (KV) Channels 3 items
  3. Phosphodiesterases (PDEs) 1 item
  4. Voltage-gated Sodium (NaV) Channels 8 items
  5. Trk Receptors 1 item
  6. EGFR 1 item
  7. CFTR 1 item
  8. Topoisomerases 1 item
  9. Cytochrome P450 (CYP450) 2 items
  10. DNA Methyltransferases 1 item
  11. PKC 1 item
  12. Ca2 /calmodulin-dependent protein kinases (CaMKs) 3 items
  13. Calcium ionophores 1 item
  14. Voltage-gated Calcium Channels (CaV) 11 items
  15. Mitochondrial apoptosis-induced channel (MAC) 1 item
  16. D1 and D5 Receptors 1 item
  17. D2 Receptors 1 item
  18. D3 Receptors 1 item
  19. Na /H Exchangers (NHEs) 1 item
  20. Fatty-acid-binding proteins (FABPs) 1 item
  21. Delayed rectifier outward potassium current (IKr) 1 item
  22. P2X Receptors 1 item
  23. Calcium-activated chloride channels (CaCC) 1 item
  24. GPR35 1 item
  25. Urokinases 1 item
  26. Histamine H1 Receptors 3 items
  27. GABAA Receptors 1 item
  28. Organic anion transporters (OATs) 1 item
  29. TRP Channel 2 items
  30. Ionophores 1 item
  31. Calcium-Activated Potassium (KCa) Channels 3 items
  32. cAMP 1 item
  33. Sulfonylurea receptors 1 item
  34. Inward Rectifier Potassium (Kir) Channels 5 items
  35. D4 Receptors 1 item
  36. voltage-gated chloride channels 1 item
  37. sodium channels 1 item
  38. Trypsin-like protease 1 item
  39. 5-HT receptors 1 item
  40. sodium channel 2 items
  41. Antibiotic 1 item
  42. Calcium-Sensing Receptors (CaSRs) 1 item
  43. 5-HT4 Receptor 1 item
  44. TRPA 1 item
  45. glutamate release 1 item
  46. TRPC channel 1 item
Reported Experiments
  1. Animal Experiments 5 items
  2. Cell Experiments 5 items
Related Disease
  1. Diabetes 1 item
  2. Type 2 Diabetes 2 items