Search results for: 'research-area gpcr-g-protein'
- Tenovin-1Catalog No. :A4203SIRT2 inhibitor, activates p53Tenovin-1, a small molecule discovered by a cell-based screen, is a bio-active activator of p53 that elevates the levels of p53 protein, p53-downstream target p21CIP/WAF1 protein and mRNA and protects p53 from mdm2-mediated degradation with little impact on p53 synthesis.
- PhiKan 083Catalog No. :A4481p53 stabilizerp53 stabilizing agent; preferentially binds mutated (Y220C) p53 over wild-type p53 at a site distinct from functional DNA/protein interaction regions. Slows rate of thermal denaturation of p53-Y220C.