Search results for: 'research-area gpcr-g-protein'
- VRT752271Catalog No. :B1106ERK1/ERK2 inhibitorVRT752271 is a pyrrole inhibitors of ERK protein kinase.
- A-674563Catalog No. :A8616Akt1/PKA/CDK2 inhibitor,potent and selectiveA-674563 is a potent selective protein kinase B/Akt inhibitor with an IC50 of 14 nM.
- XMD8-92Catalog No. :A3943BMK1/ERK5 inhibitor,highly selectiveIC50: XMD8-92 has been synthesized as a potent inhibitor of Mitogen-activated protein kinase 7 (MAPK7/BMK1; Kd = 80 nM). XMD8-92 blocks EGF-induced activation of BMK1 with IC50 of 240 nM .
- XMD17-109Catalog No. :A3942ERK-5 inhibitorThe protein kinase ERK5 (MAPK7) is an emerging drug target for a variety of indications, especially for cancer where it plays a key role mediating cell proliferation, survival, angiogenesis, and epithelial−mesenchymal transition.