Search results for: 'research-area gpcr-g-protein'
- Tenovin-1Catalog No. :A4203SIRT2 inhibitor, activates p53Tenovin-1, a small molecule discovered by a cell-based screen, is a bio-active activator of p53 that elevates the levels of p53 protein, p53-downstream target p21CIP/WAF1 protein and mRNA and protects p53 from mdm2-mediated degradation with little impact on p53 synthesis.
- PhiKan 083Catalog No. :A4481p53 stabilizerp53 stabilizing agent; preferentially binds mutated (Y220C) p53 over wild-type p53 at a site distinct from functional DNA/protein interaction regions. Slows rate of thermal denaturation of p53-Y220C.
- Cathepsin G Inhibitor ICatalog No. :A8174Cathepsin G inhibitorCathepsin G (EC 22.214.171.124, chymotrypsin-like proteinase, neutral proteinase) is an enzymatic protein belonging to the peptidase or protease families.
- Pepstatin ACatalog No. :A2571Aspartic proteinases inhibitor
Pepstatin A is a well-known inhibitor of aspartic proteinases with IC50 values of 15 μM, 2 μM, < 5 nM and < 40 nM for human renin, HIV protease, pepsin and cathepsin D, respectively.