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  • Search results for: 'research-area gpcr-g-protein'

Search results for: 'research-area gpcr-g-protein'

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Items 1-10 of 13

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  1. PF-04929113 (SNX-5422)
    A4065 PF-04929113 (SNX-5422)
    Target: HSP90
    Summary: Hsp90 inhibitor,potent and selective
      ≥23.85 mg/mL
      <2.56 mg/mL
      <2.38 mg/mL
  2. NVP-BEP800
    A4064 NVP-BEP800
    Target: HSP90
    Summary: Oral Hsp90β inhibitor, novel, fully synthetic
      ≥24.7 mg/mL
      ≥16 mg/mL
      <1.98 mg/mL
  3. BIIB021
    A4058 BIIB021
    Target: HSP90
    Summary: Hsp90 inhibitor,selective and competitive
      ≥14.95 mg/mL
      <2.44 mg/mL
      <2.52 mg/mL
  4. Butein
    A2689 Butein
    Target: Src|STAT|EGFR|Angiotensin-Converting Enzymes (ACEs)|5-Lipoxygenases|PTK|enoyl-acyl-carrier protein reductase
    Summary: Protein kinase inhibitor
      ≥13.6 mg/mL
  5. Fasudil (HA-1077) HCl
    A5734 Fasudil (HA-1077) HCl
     1 Citation
    Target: ROCK
    Summary: Protein kinase inhibitor
      ≥16.4 mg/mL
      ≥4.81 mg/mL
      ≥50 mg/mL
  6. XL-888
    A4388 XL-888
     1 Citation
    Target: HSP90
    Summary: Hsp90 inhibitor
      ≥18.2 mg/mL
      <2.56 mg/mL
      <2.38 mg/mL
  7. KW-2478
    A4062 KW-2478
    Target: HSP90
    Summary: Potent Hsp90 inhibitor, novel, non-ansamycin,
      ≥100 mg/mL
  8. IPI-504 (Retaspimycin hydrochloride)
    A4061 IPI-504 (Retaspimycin hydrochloride)
     3 Citation
    Target: HSP90
    Summary: Hsp90 inhibitor,novel, potent,selective
      ≥26.1 mg/mL
      ≥100 mg/mL
      <2.5 mg/mL
  9. AUY922 (NVP-AUY922)
    A4057 AUY922 (NVP-AUY922)
     1 Citation
    Target: HSP90
    Summary: Potent Hsp90 inhibitor
      ≥23.3 mg/mL
      ≥100.6 mg/mL
      <2.57 mg/mL
  10. AT13387
    A4056 AT13387
    Target: HSP90
    Summary: Hsp90 inhibitor
      ≥13.25 mg/mL
      ≥47.7 mg/mL
      <2.54 mg/mL

Items 1-10 of 13

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Category
Specificity
  1. Selective 10 items
Reversibility
  1. Reversible 1 item
  2. Irreversible 1 item
Target
  1. Cyclin-Dependent Kinases 4 items
  2. Proteasome 1 item
  3. Cathepsins 2 items
  4. Inhibitor of apoptosis proteins (IAP) 1 item
  5. Akt 1 item
  6. Bcl-2 2 items
  7. PI3K 2 items
  8. CXCR 1 item
  9. Raf 2 items
  10. Aurora Kinases 1 item
  11. Glycoproteins 1 item
  12. Gap Junctions 1 item
  13. MDM2 1 item
  14. EZH2 1 item
  15. Bromodomains 3 items
  16. FLT3 1 item
  17. GSK-3 4 items
  18. P-glycoprotein (P-gp) 2 items
  19. Chk 1 item
  20. VEGFR 2 items
  21. PDGFR 3 items
  22. c-Kit 3 items
  23. p38 2 items
  24. PKB 1 item
  25. Bcr-Abl 2 items
  26. MEK 1 item
  27. DOT1L 1 item
  28. Sir2-like Family Deacetylases (Sirtuins) 2 items
  29. Voltage-gated Sodium (NaV) Channels 1 item
  30. PP1 1 item
  31. PP2A 1 item
  32. Ribosomal s6 kinases (RSK) 1 item
  33. MET 1 item
  34. Src 3 items
  35. Trk Receptors 2 items
  36. STAT 3 items
  37. Estrogen and Related Receptors 1 item
  38. EGFR 2 items
  39. ROCK 2 items
  40. Monocyte chemotactic proteins 1 item
  41. FAK 3 items
  42. BMP and Other Activin Receptors 3 items
  43. JAK 1 item
  44. p300 1 item
  45. DNA-PK 2 items
  46. HSP90 8 items
  47. AMPK 2 items
  48. CFTR 2 items
  49. Topoisomerases 1 item
  50. Cytochrome P450 (CYP450) 1 item
  51. Ksp 2 items
  52. Renin 1 item
  53. HIV proteases 1 item
  54. Pepsins 1 item
  55. Serine Proteases 1 item
  56. ERK 4 items
  57. PKC 9 items
  58. Ca2 /calmodulin-dependent protein kinases (CaMKs) 4 items
  59. SMYD2 1 item
  60. CREBBP 1 item
  61. EP300 1 item
  62. RAD51 1 item
  63. Pyk2 3 items
  64. Melanocortin (MC) Receptors 1 item
  65. Trypsin 1 item
  66. Chymotrypsin 1 item
  67. Kallikrein 1 item
  68. Trypsinogen 1 item
  69. CETP 2 items
  70. PKG 1 item
  71. PKA 3 items
  72. Myosin light chain kinases (MLCKs) 1 item
  73. D1 and D5 Receptors 1 item
  74. D2 Receptors 1 item
  75. D3 Receptors 1 item
  76. CaM-KK 1 item
  77. MK2 1 item
  78. Fatty-acid-binding proteins (FABPs) 1 item
  79. Angiotensin-Converting Enzymes (ACEs) 1 item
  80. RSK 1 item
  81. Free Fatty Acid Receptors 2 items
  82. phosphatases 1 item
  83. ATM/ATR 1 item
  84. Farnesyl Diphosphate Synthases 1 item
  85. Cryptochromes 1 item
  86. SRPK1 1 item
  87. P2X Receptors 1 item
  88. Carbonic Anhydrases 1 item
  89. G9a 1 item
  90. c-Fyn 1 item
  91. TAK1 1 item
  92. FoxM1 1 item
  93. Apoptosis Inducers 1 item
  94. 5-Lipoxygenases 1 item
  95. Cdc7 1 item
  96. D4 Receptors 1 item
  97. Hydroxylases 1 item
  98. BACE 1 item
  99. GPR40 1 item
  100. DPP-4 1 item
  101. PP4 1 item
  102. Nonstructural protein 5B (NS5B) 1 item
  103. ADAMs 1 item
  104. PTP 1 item
  105. ERAD 1 item
  106. p53 2 items
  107. cysteine protease 1 item
  108. PTK 1 item
  109. Lck 1 item
  110. prolactin secretion 1 item
  111. gonadotropin release 1 item
  112. p21 1 item
  113. Protein Tyrosine Phosphatases 1 item
  114. alkaline phosphatases 1 item
  115. ATPases 1 item
  116. glutamate release 1 item
  117. PKD 1 item
  118. enoyl-acyl-carrier protein reductase 1 item
  119. FKBP 1 item
  120. Bcl-w 1 item
  121. Bax 1 item
Reported Experiments
  1. Animal Experiments 11 items
  2. Cell Experiments 8 items
Related Disease
  1. Breast Cancer 3 items
  2. Cancer 8 items
  3. Colon Cancer 1 item
  4. Lung Cancer 2 items
  5. Melanoma 2 items
  6. Multiple Myeloma 2 items
  7. Non-small Cell Lung Cancer 1 item
  8. Pancreatic Cancer 1 item
  9. Prostate Cancer 3 items