Search results for: 'research-area gpcr-g-protein'
- ML347Catalog No. :B3688BMP receptor inhibitor,potent and selectiveML347 is a potent and selective inhibitor of bone morphogenetic protein (BMP) receptor with IC50 value of 32nM against ALK2 .
- DMH-1Catalog No. :B3686Selective BMP ALK2 receptorDMH1 is a small molecule inhibitor of bone morphogenetic protein (BMP) signaling with IC50 value of 107.9nM against ALK2 .
- LDN-193189Catalog No. :A8324ALK inhibitor,potent and selectiveLDN193189 is a selective transcriptional activity morphogenetic protein (BMP) type I receptors inhibitor. It inhibits activin receptor-like kinase-2 (ALK2) and ALK3 with IC50 values of 5 nM and 30 nM, respectively .
- AZD7762Catalog No. :A5919Checkpoint kinase inhibitor,ATP competitiveAZD7762 is a novel ATP competitive inhibitor of checkpoint kinases. Chk family checkpoint kinases include Chk1 and Chk2. They are activated in response to DNA damage and phosphorylate CDC25A, CDC25C protein phosphatases, which delay cell cycle progression. Therefore, Chk activation initiates cell cycle checkpoint, causes cell cycle arrest, and allows DNA repair.