Search results for: 'research-area gpcr-g-protein'
- ML347Catalog No. :B3688BMP receptor inhibitor,potent and selectiveML347 is a potent and selective inhibitor of bone morphogenetic protein (BMP) receptor with IC50 value of 32nM against ALK2 .
- DMH-1Catalog No. :B3686Selective BMP ALK2 receptorDMH1 is a small molecule inhibitor of bone morphogenetic protein (BMP) signaling with IC50 value of 107.9nM against ALK2 .
- LDN-193189Catalog No. :A8324ALK inhibitor,potent and selectiveLDN193189 is a selective transcriptional activity morphogenetic protein (BMP) type I receptors inhibitor. It inhibits activin receptor-like kinase-2 (ALK2) and ALK3 with IC50 values of 5 nM and 30 nM, respectively .
- EPZ005687Catalog No. :A4171EZH2 inhibitor,potent and selective
EPZ005687 is a potent inhibitor of EZH2, an enzymatic subunit of polycomb repressive complex 2 (PRC2) catalyzing the methylation of histone H3 lysine 27 (H3K27), that inhibits EZH2 with a value of inhibition constant Ki of 24 nM, which is 500-fold and 50-fold greater in selectivity than 15 other protein methyltransferases and closely related EZH1 respectively.