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  • Search results for: 'research-area gpcr-g-protein'

Search results for: 'research-area gpcr-g-protein'

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  1. GW9508
    GW9508
    Catalog No. :
    A1709
    FFA1/GPR40 agonist,potent and selective

    GW9508 is a selective agonist of GPR40 and 120 with pEC50 value of 7.32 ± 0.03 and 5.46 ± 0.09, respectively .

  2. TUG-770
    TUG-770
    Catalog No. :
    A3895
    FFA1/GPR40 agonist
    TUG-770 is a highly potent free fatty acid receptor 1 (FFA1/GPR40) agonist for treatment of type 2 diabetes.
  3. Butein
    Butein
    Catalog No. :
    A2689
    Protein kinase inhibitor
    Butein, a chalconoid has anti-oxidant effect, which has various pharmacological effects.
  4. Epidermal Growth Factor (EGF), human recombinant
    Epidermal Growth Factor (EGF), human recombinant
    Catalog No. :
    P1008
    EGF, expressed in E.Coli, His-tag, suitable for cell culture.

    Human epidermal growth factor (EGF) is a member of the EGF-family and plays an important role in the regulation of cell growth, proliferation, and differentiation through binding to its receptor EGFR.

  5. ML347
    ML347
    Catalog No. :
    B3688
    BMP receptor inhibitor,potent and selective
    ML347 is a potent and selective inhibitor of bone morphogenetic protein (BMP) receptor with IC50 value of 32nM against ALK2 .
  6. DMH-1
    DMH-1
    Catalog No. :
    B3686
    Selective BMP ALK2 receptor
    DMH1 is a small molecule inhibitor of bone morphogenetic protein (BMP) signaling with IC50 value of 107.9nM against ALK2 .
  7. LDN-193189
    LDN-193189
    Catalog No. :
    A8324
    ALK inhibitor,potent and selective
    LDN193189 is a selective transcriptional activity morphogenetic protein (BMP) type I receptors inhibitor. It inhibits activin receptor-like kinase-2 (ALK2) and ALK3 with IC50 values of 5 nM and 30 nM, respectively .

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  1. Target BMP and Other Activin Receptors Remove This Item
  2. Target Free Fatty Acid Receptors Remove This Item
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Category
  • Protein 1item
  • Signaling Pathways 6items
Specificity
  1. Selective 5 items
Target
  1. Cyclin-Dependent Kinases 4 items
  2. Proteasome 1 item
  3. Cathepsins 2 items
  4. Inhibitor of apoptosis proteins (IAP) 1 item
  5. Akt 1 item
  6. Bcl-2 2 items
  7. PI3K 2 items
  8. CXCR 1 item
  9. Raf 2 items
  10. Aurora Kinases 1 item
  11. Glycoproteins 1 item
  12. Gap Junctions 1 item
  13. MDM2 1 item
  14. EZH2 1 item
  15. Bromodomains 3 items
  16. FLT3 1 item
  17. GSK-3 4 items
  18. P-glycoprotein (P-gp) 2 items
  19. Chk 1 item
  20. VEGFR 2 items
  21. PDGFR 3 items
  22. c-Kit 3 items
  23. p38 2 items
  24. PKB 1 item
  25. Bcr-Abl 2 items
  26. MEK 1 item
  27. DOT1L 1 item
  28. Sir2-like Family Deacetylases (Sirtuins) 2 items
  29. Voltage-gated Sodium (NaV) Channels 1 item
  30. PP1 1 item
  31. PP2A 1 item
  32. Ribosomal s6 kinases (RSK) 1 item
  33. MET 1 item
  34. Src 3 items
  35. Trk Receptors 2 items
  36. STAT 3 items
  37. Estrogen and Related Receptors 1 item
  38. EGFR 2 items
  39. ROCK 2 items
  40. Monocyte chemotactic proteins 1 item
  41. FAK 3 items
  42. BMP and Other Activin Receptors 3 items
  43. JAK 1 item
  44. p300 1 item
  45. DNA-PK 2 items
  46. HSP90 8 items
  47. AMPK 2 items
  48. CFTR 2 items
  49. Topoisomerases 1 item
  50. Cytochrome P450 (CYP450) 1 item
  51. Ksp 2 items
  52. Renin 1 item
  53. HIV proteases 1 item
  54. Pepsins 1 item
  55. Serine Proteases 1 item
  56. ERK 4 items
  57. PKC 9 items
  58. Ca2 /calmodulin-dependent protein kinases (CaMKs) 4 items
  59. SMYD2 1 item
  60. CREBBP 1 item
  61. EP300 1 item
  62. RAD51 1 item
  63. Pyk2 3 items
  64. Melanocortin (MC) Receptors 1 item
  65. Trypsin 1 item
  66. Chymotrypsin 1 item
  67. Kallikrein 1 item
  68. Trypsinogen 1 item
  69. CETP 2 items
  70. PKG 1 item
  71. PKA 3 items
  72. Myosin light chain kinases (MLCKs) 1 item
  73. D1 and D5 Receptors 1 item
  74. D2 Receptors 1 item
  75. D3 Receptors 1 item
  76. CaM-KK 1 item
  77. MK2 1 item
  78. Fatty-acid-binding proteins (FABPs) 1 item
  79. Angiotensin-Converting Enzymes (ACEs) 1 item
  80. RSK 1 item
  81. Free Fatty Acid Receptors 2 items
  82. phosphatases 1 item
  83. ATM/ATR 1 item
  84. Farnesyl Diphosphate Synthases 1 item
  85. Cryptochromes 1 item
  86. SRPK1 1 item
  87. P2X Receptors 1 item
  88. Carbonic Anhydrases 1 item
  89. G9a 1 item
  90. c-Fyn 1 item
  91. TAK1 1 item
  92. Histamine H1 Receptors 1 item
  93. FoxM1 1 item
  94. Apoptosis Inducers 1 item
  95. 5-Lipoxygenases 1 item
  96. Cdc7 1 item
  97. D4 Receptors 1 item
  98. Hydroxylases 1 item
  99. BACE 1 item
  100. GPR40 1 item
  101. DPP-4 1 item
  102. PP4 1 item
  103. Nonstructural protein 5B (NS5B) 1 item
  104. ADAMs 1 item
  105. PTP 1 item
  106. ERAD 1 item
  107. p53 2 items
  108. cysteine protease 1 item
  109. PTK 1 item
  110. Lck 1 item
  111. prolactin secretion 1 item
  112. gonadotropin release 1 item
  113. p21 1 item
  114. Protein Tyrosine Phosphatases 1 item
  115. alkaline phosphatases 1 item
  116. ATPases 1 item
  117. glutamate release 1 item
  118. TRPC channel 1 item
  119. PKD 1 item
  120. enoyl-acyl-carrier protein reductase 1 item
  121. FKBP 1 item
  122. Bcl-w 1 item
  123. Bax 1 item
Reported Experiments
  1. Animal Experiments 4 items
  2. Cell Experiments 2 items
Related Disease
  1. Cancer 1 item
  2. Lung Cancer 1 item
  3. Type 2 Diabetes 1 item