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  • Search results for: 'research-area gpcr-g-protein angiotensin-receptor'

Search results for: 'research-area gpcr-g-protein angiotensin-receptor'

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  1. Imatinib (STI571)
    B2171 Imatinib (STI571)
    Target: PDGFR|c-Kit|Bcr-Abl
    Summary: Protein-tyrosine kinase inhibitor
      ≥24.68 mg/mL
  2. Pazopanib (GW-786034)
    A3022 Pazopanib (GW-786034)
    Target: CSF-1R|VEGFR|PDGFR|c-Kit|FGFR
    Summary: VEGFR/PDGFR/FGFR inhibitor
      ≥10.95 mg/mL
      <2.52 mg/mL
      <2.76 mg/mL
  3. Sorafenib
    A3009 Sorafenib
     2 Citation
    Target: Raf|VEGFR
    Summary: Raf kinases and tyrosine kinases inhibitor
      ≥23.25 mg/mL
  4. Telatinib (BAY 57-9352)
    A8550 Telatinib (BAY 57-9352)
    Target: VEGFR|PDGFR|c-Kit
    Summary: VEGFR-2/-3,PDGFR-β and c-Kit inhibitor
      ≥20.5 mg/mL
  5. RAF265
    A8313 RAF265
    Target: Raf|VEGFR
    Summary: Multiple intracellular kinases inhibitor
      ≥25.9 mg/mL
      ≥7.97 mg/mL
      <2.52 mg/mL
  6. AZD2932
    B5835 AZD2932
    Target: FLT3|VEGFR|PDGFR|c-Kit
    Summary: inhibitor of VEGFR-2, PDGFRβ, Flt-3, and c-Kit
      soluble in dmso
  7. Dabrafenib Mesylate (GSK-2118436)
    A3347 Dabrafenib Mesylate (GSK-2118436)
    Target: Raf
    Summary: Inhibitor of BRAF(V600) mutants
      ≥30.75 mg/mL
      ≥2.74 mg/mL
      <2.25 mg/mL
  8. GDC-0152
    A4224 GDC-0152
     2 Citation
    Target: Inhibitor of apoptosis proteins (IAP)
    Summary: IAP antagonist,potent amd samll-molecule
      ≥24.95 mg/mL
      ≥50.6 mg/mL
      <2.44 mg/mL
  9. PLX-4720
    A3016 PLX-4720
     1 Citation
    Target: Raf
    Summary: BRAF kinase inhibitor
      ≥20.69 mg/mL
  10. Dovitinib (TKI258) Lactate
    B5953 Dovitinib (TKI258) Lactate
    Target: CSF-1R|FLT3|VEGFR|PDGFR|c-Kit|FGFR
    Summary: Oral tyrosine kinase inhibitor (TKI) against FGFR1–3, VEGFR1–3, and platelet-derived growth factor receptor (PDGFR).
      ≥168.2 mg/mL

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Specificity
  1. Selective 12 items
Target
  1. Cyclin-Dependent Kinases 4 items
  2. Adenosine A2A Receptors 4 items
  3. Proteasome 1 item
  4. Cathepsins 2 items
  5. Histone Deacetylases (HDACs) 1 item
  6. Inhibitor of apoptosis proteins (IAP) 1 item
  7. Akt 1 item
  8. Bcl-2 2 items
  9. PI3K 2 items
  10. CXCR 6 items
  11. Raf 5 items
  12. Aurora Kinases 3 items
  13. CSF-1R 3 items
  14. Glycoproteins 1 item
  15. Gap Junctions 1 item
  16. MDM2 1 item
  17. EZH2 1 item
  18. Bromodomains 3 items
  19. Androgen Receptors 6 items
  20. Voltage-gated Potassium (KV) Channels 2 items
  21. FLT3 4 items
  22. GSK-3 4 items
  23. Farnesoid X receptors (FXRs) 2 items
  24. LPA Receptors 4 items
  25. P-glycoprotein (P-gp) 2 items
  26. Chk 1 item
  27. Eph Receptors 1 item
  28. VEGFR 18 items
  29. PDGFR 14 items
  30. c-Kit 9 items
  31. RET 1 item
  32. IRAK 3 items
  33. Phosphodiesterases (PDEs) 2 items
  34. p38 3 items
  35. PKB 1 item
  36. Bcr-Abl 2 items
  37. MEK 1 item
  38. DOT1L 1 item
  39. FGFR 7 items
  40. Insulin-like growth factor receptors(IGFRs) 1 item
  41. CGRP receptors 2 items
  42. GABAB Receptors 2 items
  43. Liver X receptors (LXRs) 4 items
  44. Glucagon-like peptide 1 (GLP-1) receptors 2 items
  45. Sir2-like Family Deacetylases (Sirtuins) 2 items
  46. Voltage-gated Sodium (NaV) Channels 1 item
  47. PP1 1 item
  48. PP2A 1 item
  49. Ribosomal s6 kinases (RSK) 1 item
  50. MET 2 items
  51. Src 4 items
  52. RARs 4 items
  53. Trk Receptors 4 items
  54. NMDA Receptors 2 items
  55. STAT 3 items
  56. Endothelin receptors 1 item
  57. Estrogen and Related Receptors 7 items
  58. EGFR 11 items
  59. ROCK 2 items
  60. Purinergic (P2Y) Receptors 1 item
  61. Monocyte chemotactic proteins 1 item
  62. FAK 4 items
  63. BMP and Other Activin Receptors 4 items
  64. JAK 1 item
  65. p300 1 item
  66. Syk 1 item
  67. Progesterone Receptors 3 items
  68. DNA-PK 2 items
  69. HSP90 8 items
  70. AMPK 2 items
  71. CCR 1 item
  72. Angiotensin AT2 Receptors 3 items
  73. CFTR 2 items
  74. Topoisomerases 1 item
  75. Cytochrome P450 (CYP450) 2 items
  76. M3 Receptors 3 items
  77. Ksp 2 items
  78. Renin 1 item
  79. HIV proteases 1 item
  80. Pepsins 1 item
  81. ErbB 3 items
  82. Toll-like receptors (TLRs) 3 items
  83. Serine Proteases 1 item
  84. Calcitonin and Related Receptors 1 item
  85. ERK 4 items
  86. c-MET 2 items
  87. PKC 10 items
  88. CysLT1 1 item
  89. M1 Receptors 2 items
  90. Ca2 /calmodulin-dependent protein kinases (CaMKs) 6 items
  91. SMYD2 1 item
  92. CREBBP 1 item
  93. EP300 1 item
  94. Protease-Activated Receptors 1 item
  95. Lyn 1 item
  96. RAD51 1 item
  97. HER2 1 item
  98. Pyk2 3 items
  99. 5-HT2 Receptors 10 items
  100. S1P receptors 3 items
  101. Voltage-gated Calcium Channels (CaV) 1 item
  102. Insulin and Insulin-like Receptors 4 items
  103. CB1 Receptors 3 items
  104. Melanocortin (MC) Receptors 1 item
  105. ALK 4 items
  106. Trypsin 1 item
  107. Chymotrypsin 1 item
  108. Kallikrein 1 item
  109. Trypsinogen 1 item
  110. CETP 2 items
  111. NK1 Receptors 1 item
  112. PKG 1 item
  113. PKA 3 items
  114. Myosin light chain kinases (MLCKs) 1 item
  115. GPR30 1 item
  116. D1 and D5 Receptors 5 items
  117. D2 Receptors 9 items
  118. D3 Receptors 5 items
  119. 5-HT1 Receptors 9 items
  120. 5-HT7 Receptors 2 items
  121. CaM-KK 1 item
  122. AMPA 1 item
  123. MK2 1 item
  124. Fatty-acid-binding proteins (FABPs) 1 item
  125. 5-HT3 Receptors 6 items
  126. Angiotensin-Converting Enzymes (ACEs) 6 items
  127. Tie-2 1 item
  128. RSK 1 item
  129. Free Fatty Acid Receptors 3 items
  130. phosphatases 1 item
  131. ATM/ATR 1 item
  132. C5a receptors 1 item
  133. Histamine H4 Receptors 2 items
  134. Farnesyl Diphosphate Synthases 1 item
  135. Cryptochromes 1 item
  136. Melatonin Receptors 2 items
  137. SRPK1 1 item
  138. P2X Receptors 3 items
  139. Carbonic Anhydrases 1 item
  140. G9a 1 item
  141. Adenosine A2B Receptors 1 item
  142. Glutamate (Metabotropic) Group I Receptors 2 items
  143. NPY Receptors 1 item
  144. c-Fyn 1 item
  145. Leukotriene and Related Receptors 2 items
  146. TAK1 1 item
  147. Histamine H1 Receptors 13 items
  148. Sigma Receptors 2 items
  149. Nur77 1 item
  150. Na /K /Cl- Symporters (NKCCs) 1 item
  151. GABAA Receptors 4 items
  152. Histamine H2 Receptors 1 item
  153. TRP Channel 1 item
  154. Norepinephrine transporter 1 item
  155. 5-HT Transporters 1 item
  156. FoxM1 1 item
  157. Apoptosis Inducers 1 item
  158. M2 Receptors 2 items
  159. 5-Lipoxygenases 1 item
  160. CB2 Receptors 2 items
  161. Glucocorticoid Receptors 5 items
  162. Calcium-Activated Potassium (KCa) Channels 1 item
  163. 5-HT4 Receptors 1 item
  164. AChE 1 item
  165. Insulin Receptors 1 item
  166. Inward Rectifier Potassium (Kir) Channels 2 items
  167. CRTH2 1 item
  168. Cdc7 1 item
  169. Angiotensin AT1 Receptors 4 items
  170. D4 Receptors 2 items
  171. M4 Receptors 1 item
  172. M5 Receptors 1 item
  173. Hydroxylases 1 item
  174. Adenine receptors 1 item
  175. BACE 1 item
  176. GPR40 1 item
  177. Glucagon Receptors 1 item
  178. DPP-4 1 item
  179. DREADD Ligands 1 item
  180. PP4 1 item
  181. c-RET 1 item
  182. Nonstructural protein 5B (NS5B) 1 item
  183. ETA Receptors 2 items
  184. ETB Receptors 1 item
  185. AChR 4 items
  186. dopamine receptor 1 item
  187. 5-HT1 Receptor 3 items
  188. 5-HT2 Receptor 2 items
  189. interleukin receptor 1 item
  190. ADAMs 1 item
  191. PTP 1 item
  192. endothelin receptor 1 item
  193. PARs 1 item
  194. AXL 1 item
  195. ERAD 1 item
  196. p53 2 items
  197. adrenoceptor 1 item
  198. c-Fms tyrosine kinase 1 item
  199. PAR 2 items
  200. human lyase 1 item
  201. insulin 1 item
  202. Smoothened receptor 1 item
  203. cysteine protease 1 item
  204. PPAR 2 items
  205. prostaglandin FP receptor 1 item
  206. Vitamin D receptors (VDRs) 2 items
  207. cannabinoid receptor 1 item
  208. Calcium-Sensing Receptors (CaSRs) 2 items
  209. adrenergic receptor 4 items
  210. 5-HT4 Receptor 1 item
  211. TRPA 1 item
  212. Prostanoid Receptors 1 item
  213. Retinoid X receptors (RXR) 1 item
  214. constitutive androstane receptor (CAR) 1 item
  215. NPFF receptor 1 item
  216. Pregnane X receptor(PXR) 1 item
  217. Aryl hydrocarbon receptors (AHRs) 1 item
  218. PTK 1 item
  219. AMPA Receptors 1 item
  220. Lck 1 item
  221. SERT 1 item
  222. Thrombin Receptor 1 item
  223. prolactin secretion 1 item
  224. gonadotropin release 1 item
  225. Vitamin D 1 item
  226. 5-HT receptor 1 item
  227. p21 1 item
  228. NOP Receptors 1 item
  229. Protein Tyrosine Phosphatases 1 item
  230. alkaline phosphatases 1 item
  231. ATPases 1 item
  232. Dopamine receptor 1 item
  233. Histamine receptor 1 item
  234. glutamate release 1 item
  235. PAFR 1 item
  236. TRPC channel 1 item
  237. PKD 1 item
  238. P2Y Receptors 1 item
  239. enoyl-acyl-carrier protein reductase 1 item
  240. FKBP 1 item
  241. Bcl-w 1 item
  242. tropomyosin receptor kinase 1 item
  243. FXR 1 item
  244. GABAA receptor 1 item
  245. ghrelin receptor 1 item
  246. Androgen Receptor 1 item
  247. Substance P/NK1 Receptor 1 item
  248. Bax 1 item
Reported Experiments
  1. Animal Experiments 16 items
  2. Cell Experiments 11 items
Related Disease
  1. Adrenocortical Carcinoma 1 item
  2. Bladder Cancer 1 item
  3. Breast Cancer 3 items
  4. Cancer 13 items
  5. Clear Cell Renal Cell Carcinoma 1 item
  6. Colorectal Cancer 4 items
  7. Glioblastoma 2 items
  8. Liver Cancer 1 item
  9. Melanoma 2 items
  10. Multiple Myeloma 1 item
  11. Pancreatic Cancer 1 item
  12. Renal Cell Carcinoma 1 item
  13. Thyroid Cancer 2 items