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  • Search results for: 'research-area epigenetics sirtuin'

Search results for: 'research-area epigenetics sirtuin'

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  1. Tenovin-6
    A8302 Tenovin-6
    Target: Sir2-like Family Deacetylases (Sirtuins)
    Summary: SIRT inhibitor and p53 activator
      ≥22.75 mg/mL
      ≥2.62 mg/mL
      <2.02 mg/mL
  2. SRT2104 (GSK2245840)
    A3821 SRT2104 (GSK2245840)
     1 Citation
    Target: Sir2-like Family Deacetylases (Sirtuins)
    Summary: SIRT1 activator,selective
      ≥6.46 mg/mL
      <2.55 mg/mL
      <2.4 mg/mL
  3. SRT1720 HCl
    A4180 SRT1720 HCl
     3 Citation
    Target: Sir2-like Family Deacetylases (Sirtuins)
    Summary: SIRT1 activator
      ≥25.3 mg/mL
      <1.45 mg/mL
      ≥15.37 mg/mL
  4. Tenovin-1
    A4203 Tenovin-1
    Target: Sir2-like Family Deacetylases (Sirtuins)|p53|p21
    Summary: SIRT2 inhibitor, activates p53
      ≥15 mg/mL
      <2.51 mg/mL
      <2.45 mg/mL
  5. EX 527 (SEN0014196)
    A4181 EX 527 (SEN0014196)
     1 Citation
    Target: Sirtuin
    Summary: SIRT1 inhibitor
      ≥12.4 mg/mL
      ≥25.45 mg/mL
      <2.5 mg/mL
  6. Resveratrol
    A4182 Resveratrol
     2 Citation
    Target: Sir2-like Family Deacetylases (Sirtuins)|COX|LOX|Adenylyl cyclase|Quinone reductase
    Summary: SIRT1 activator
      ≥9.65 mg/mL
      ≥48.2 mg/mL
      <2.43 mg/mL
  7. Tubastatin A HCl
    A8547 Tubastatin A HCl
     1 Citation
    Target: Histone Deacetylases (HDACs)
    Summary: HDAC6 inhibitor,potent and selective
      ≥18.6 mg/mL
  8. NU7441 (KU-57788)
    A8315 NU7441 (KU-57788)
     4 Citation
    Target: PI3K|DNA-PK
    Summary: DNA-PK inhibitor
      ≥4.13 mg/mL
      <2.48 mg/mL
      <2.56 mg/mL
  9. EPZ-6438
    A8221 EPZ-6438
     5 Citation
    Summary: EZH2 inhibitor,potent and selective
      ≥28.637 mg/mL
      <2.39 mg/mL
      <2.4 mg/mL
  10. BI 2536
    A3965 BI 2536
     1 Citation
    Target: PLK|Bromodomain-containing proteins(BRDs)
    Summary: Plk1 inhibitor,potent and ATP-competitive
      ≥13.04 mg/mL
      ≥92.4 mg/mL
      <2.56 mg/mL

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Category
Specificity
  1. Selective 45 items
Reversibility
  1. Reversible 2 items
  2. Irreversible 1 item
Target
  1. Cyclin-Dependent Kinases 1 item
  2. Histone Deacetylases (HDACs) 17 items
  3. PI3K 1 item
  4. Aurora Kinases 14 items
  5. EZH2 1 item
  6. Bromodomains 1 item
  7. FLT3 5 items
  8. PLK 1 item
  9. VEGFR 2 items
  10. RET 1 item
  11. Bromodomain-containing proteins(BRDs) 1 item
  12. Hydrolase 1 item
  13. DOT1L 1 item
  14. FGFR 1 item
  15. Nrf2 1 item
  16. Pim 1 item
  17. Sir2-like Family Deacetylases (Sirtuins) 5 items
  18. PP1 1 item
  19. PP2A 1 item
  20. Src 2 items
  21. Trk Receptors 1 item
  22. STAT 1 item
  23. JAK 8 items
  24. DNA-PK 1 item
  25. Topoisomerases 1 item
  26. DNA Methyltransferases 2 items
  27. Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitors (HIF-PHIs) 1 item
  28. CREBBP 1 item
  29. EP300 1 item
  30. LRRK2 1 item
  31. PARP 2 items
  32. ALK 1 item
  33. Fatty-acid-binding proteins (FABPs) 1 item
  34. COX 1 item
  35. Hck 1 item
  36. O6-methylguanine-DNA-methyl-transferase (MGMT) 1 item
  37. Cytidine deaminases 1 item
  38. PP4 1 item
  39. c-RET 1 item
  40. VEGFR3/FLT4 1 item
  41. NTRK1/TRKA 1 item
  42. CSF-1R/c-Fms 1 item
  43. PTP 1 item
  44. p53 1 item
  45. LOX 1 item
  46. Adenylyl cyclase 1 item
  47. Quinone reductase 1 item
  48. Trx 1 item
  49. TYK2 1 item
  50. MUSK 1 item
  51. MAP3K 1 item
  52. p21 1 item
  53. FGR 1 item
  54. YES 1 item
  55. Fyn 1 item
  56. ARG 1 item
  57. Sirtuin 1 item
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