Search results for: 'research-area epigenetics parp'
- CYC116Catalog No. :A4125Potent Aurora A/B inhibitorCYC116 is a potent inhibitor of Aurora A/B with Ki of 8.0 nM/9.2 nM, is less potent to VEGFR2 (Ki of 44 nM), with 50-fold greater potency than CDKs, not active against PKA, Akt/PKB, PKC, no effect on GSK-3α/β, CK2, Plk1 and SAPK2A.
- TAK-901Catalog No. :A4124Novel Aurora A/B inhibitorTAK-901 is a novel inhibitor of Aurora A/B with IC50 of 21 nM/15 nM.
- ENMD-2076Catalog No. :A4130Selective Aurora A/Flt3 inhibitorENMD-2076 is a selective activator of Aurora A and VEGFR with IC50 value of 14 and 1.86 nM.
- LY2784544Catalog No. :A4147JAK2 inhibitor,highly potent and selectiveLY2784544 is a potent, selective inhibitor of JAK2 with IC50 value of 3 nM.
- TG101348 (SAR302503)Catalog No. :A4136JAK-2 inhibitor,potent and selective
TG101348, also known as SAR302503, is a potent and selective inhibitor of janus kinase 2 (JAK2), one member of a family of 4 cytoplasmic tyrosine kinases including janus kinase 1(JAK1), JAK2, janus kinase 3 (JAK3) and tyrosine kinase 2 (Tyk2), with the inhibition constant IC50 of 3 nM.