Search results for: 'research-area endocrinology-and-hormones'
- AR-42 (OSU-HDAC42)Catalog No. :A4104HDAC inhibitor,novel and potentAR-42 (also known as OSU-HDAC42), a derivative of hydroxamate-tethered phenylbutyrate, is a novel and potent inhibitor of histone deacetylase (HDAC) that potently inhibits the activity of HDAC with 50% inhibition concentration IC50 value of 16 nM and induces histone H3 acetylation, α-tubulin acetylation and p21 up-regulation, which have been considered as the hallmark indicators of HDAC inhibition.
- Simvastatin (Zocor)Catalog No. :A8522HMGCR (HMG-CoA reductase) inhibitorSimvastatin (SIM), a lactone, is white, crystalline, nonhygroscopic and powdery, practically insoluble in water (30 mcg/ml), and 0.1 (N) HCl (60 mcg/ml).