Search results for: 'research-area dna-damage'
- ZebularineCatalog No. :A1915DNA methylation inhibitor
Zebularine, a chemically stable cytidine analog containing a 2-(1H)-pyridimidinone ring, is an effective DNA methylation inhibitor which can act with DNA methyltransferases to form a covalent complex. It has been shown to cause demethylation and reactivation of a silenced and hypermethylated p16 gene.
- BMH-21Catalog No. :B4896RNA polymerase I Inhibitior
BMH-21 is a planar heterocyclic small molecule DNA intercalator with inhibition of Pol I activity at IC50 = 0.06 µM. 
- Foscarnet SodiumCatalog No. :B1946Reverse transcriptase inhibitorFoscarnet Sodium inhibits viral RNA polymerases, reverse transcriptase, and DNA polymerases through noncompetitive inhibition with dNTPs.