Search results for: 'research-area dna-damage'
- KU-0060648Catalog No. :A1769Dual DNA-PK/PI3-K inhibitor, ATP-competitive
IC50: KU-0060648 inhibited cellular DNA-PK autophosphorylation with IC50 values of 0.17 μmol/L (SW620 cells) and 0.019 μmol/L (MCF7 cells), and PI-3K–mediated AKT phosphorylation with IC50 values of 0.039 μmol/L (MCF7 cells) and more than 10 μmol/L (SW620 cells).
- FT-207 (NSC 148958)Catalog No. :B1474DNA/RNA synthesis inhibitorTegafur (also known as Ftorafur) is a chemotherapeutic 5-FU prodrug used in the treatment of cancers; is a component of tegafur-uracil.