Search results for: 'research-area dna-damage'
- EtoposideCatalog No. :A1971Topo II inhibitor
Etoposide (VP-16) is the first agent recognized as a topoisomerase II inhibitor of anticancer drug with IC50 of 59.2 μM.
- AZD8055Catalog No. :A8214MTOR inhibitor
AZD8055 is a selective inhibitor of mTOR kinase with IC50 of 0.8 nM . It competes with ATP at the ATP-binding cleft of mTOR. AZD8055 showed ~1000 fold selectivity against closely related kinases PI3K isoforms and ATM/DNA-PK . Furthermore, it had no significant activity against a panel of 260 kinases at 10 μM .
- CidofovirCatalog No. :A5790Anti-CMV drug;inhibitor of viral DNA syntheis
Cidofovir(Vistide) is an injectable antiviral medication for the treatment of cytomegalovirus (CMV) retinitis.