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  • Search results for: 'research-area dna-damage'

Search results for: 'research-area dna-damage'

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  1. DiscoveryProbe™ DNA Damage/DNA Repair Library
    DiscoveryProbe™ DNA Damage/DNA Repair Library
    Catalog No. :
    L1033
    A unique collection of 146 DNA Damage/DNA repair-related compounds for DNA damage/DNA repair research.
  2. DiscoveryProbe™ DNA Damage/DNA Repair-related Compounds Panel
    DiscoveryProbe™ DNA Damage/DNA Repair-related Compounds Panel
    Catalog No. :
    L1007
    A wide range of well-characterized bioactive molecules that covers various targets related to DNA damage/DNA repair, including ATM/ATR, HDAC, and topoisomerase etc.
  3. Trovafloxacin mesylate
    Trovafloxacin mesylate
    Catalog No. :
    A8646
    Fluoroquinolone antibiotic
    Fluoroquinolone antibiotic. Inhibits bacterial DNA topoisomerase IV and DNA gyrase and forms a stable quinolone-DNA complex with these enzymes which reversibly inhibits DNA synthesis.
  4. NU 7026
    NU 7026
    Catalog No. :
    A8649
    DNPK inhibitor,ATP-competitive and potent

    NU 7026 is a selective inhibitor of DNA-PK with IC50 value of 0.23 μM.

  5. Cytarabine
    Cytarabine
    Catalog No. :
    A8405
    cytotoxic agent, blocks DNA synthesis
    Cytarabine (AraC), an analogue of deoxycytidine, is the most effective cytotoxic agent in the treatment of acute myeloid leukemia (AML), which blocks DNA synthesis by inhibiting the function of DNA and RNA polymerases [1].
  6. Fludarabine Phosphate (Fludara)
    Fludarabine Phosphate (Fludara)
    Catalog No. :
    A8317
    Inhibits STAT1 activation and DNA synthesis

    Fludarabine phosphate is a STAT-1 activation inhibitor and a DNA synthesis inhibitor.

  7. NU7441 (KU-57788)
    NU7441 (KU-57788)
    Catalog No. :
    A8315
    DNA-PK inhibitor

    NU7441 is a selective inhibitor of DNA-dependent protein kinase (DNA-PK) with IC50 value of 13 nM .

  8. Mitomycin C
    Mitomycin C
    Catalog No. :
    A4452
    Inhibits DNA synthesis,antibiotic and antitumor agent

    Mitomycin C, a kind of antibiotic isolated from Streptomyces caespitosus or Streptomyces lavendulae, inhibits DNA synthesis through covalent mitomycin C-DNA adduct with EC50 values of 0.14μM in PC3 cells.

  9. Mithramycin A
    Mithramycin A
    Catalog No. :
    A4546
    Anticancer antibiotic
    Anticancer antibiotic that selectively binds to G-C-rich DNA in the presence of Mg2+ or Zn2+, inhibiting RNA and DNA polymerase action. Inhibits c-myc expression and induces myeloid differentiation of HL-60 promyelocytic leukemia cells.
  10. Oxaliplatin
    Oxaliplatin
    Catalog No. :
    A8648
    Antitumor agent

    Antitumor agent that forms platinum-DNA adducts.

Items 1-10 of 337

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