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  • Search results for: 'research-area cell-cycle aurora-kinase-a'

Search results for: 'research-area cell-cycle aurora-kinase-a'

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  1. PF-03814735
    A4128 PF-03814735
    Target: Aurora Kinases
    Summary: Aurora A/B inhibitor
      soluble in dmso
  2. GSK1070916
    A4127 GSK1070916
    Target: Aurora Kinases
    Summary: Aurora B/C inhibitor
      ≥25.4 mg/mL
  3. MLN8054
    A4114 MLN8054
    Target: Aurora Kinases
    Summary: Aurora A inhibitor
      ≥39.05 mg/mL
      insoluble in etoh
      insoluble in h2o
  4. AZD1152
    A3214 AZD1152
     1 Citation
    Target: Aurora Kinases
    Summary: Aurora B kinase inhibitor,highly potent and selective
      ≥5.88 mg/mL
      insoluble in etoh
      insoluble in h2o
  5. TC-A 2317 hydrochloride
    A4489 TC-A 2317 hydrochloride
    Target: Aurora Kinases
    Summary: Aurora kinase A inhibitor,potent and selective
      <39.29 mg/mL
  6. KW 2449
    A4123 KW 2449
    Target: Aurora Kinases|FLT3|Bcr-Abl
    Summary: Multikinase inhibitor
      ≥16.6 mg/mL
      insoluble in etoh
      insoluble in h2o
  7. Reversine
    A3760 Reversine
    Target: Aurora Kinases
    Summary: A3 adenosine receptor antagonist,ARK-1/-2/-3 inhibitor
      ≥19.65 mg/mL
      ≥6.69 mg/mL
      insoluble in h2o
  8. AZD7762
    A5919 AZD7762
    Target: Chk
    Summary: Checkpoint kinase inhibitor,ATP competitive
      ≥18.1 mg/mL
      insoluble in etoh
      insoluble in h2o
  9. MK-8776 (SCH-900776)
    A8477 MK-8776 (SCH-900776)
    Target: Chk
    Summary: Chk1 inhibitor,potent and selective
      ≥18.8 mg/mL
      insoluble in etoh
      insoluble in h2o
  10. Fasudil (HA-1077) HCl
    A5734 Fasudil (HA-1077) HCl
     1 Citation
    Target: ROCK
    Summary: Protein kinase inhibitor
      ≥16.4 mg/mL
      ≥4.81 mg/mL
      ≥50 mg/mL

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  • Signaling Pathways 354items
Reversibility
  1. Reversible 33 items
  2. Irreversible 12 items
Target
  1. Caspases 6 items
  2. Cyclin-Dependent Kinases 22 items
  3. Proteasome 4 items
  4. Cathepsins 1 item
  5. Histone Deacetylases (HDACs) 12 items
  6. Inhibitor of apoptosis proteins (IAP) 1 item
  7. Akt 1 item
  8. Bcl-2 2 items
  9. PI3K 12 items
  10. Raf 7 items
  11. Aurora Kinases 14 items
  12. Bcl-xl 1 item
  13. CSF-1R 2 items
  14. Glycoproteins 1 item
  15. MDM2 1 item
  16. EZH2 3 items
  17. mTOR 6 items
  18. AP-1 2 items
  19. MMP 1 item
  20. Myosin II ATPases 1 item
  21. FLT3 8 items
  22. GSK-3 7 items
  23. LPA Receptors 1 item
  24. P-glycoprotein (P-gp) 3 items
  25. PLK 5 items
  26. Chk 5 items
  27. Eph Receptors 3 items
  28. VEGFR 20 items
  29. PDGFR 14 items
  30. c-Kit 6 items
  31. RET 3 items
  32. IRAK 2 items
  33. Bromodomain-containing proteins(BRDs) 1 item
  34. Phosphodiesterases (PDEs) 1 item
  35. Hydrolase 1 item
  36. p38 6 items
  37. PKB 1 item
  38. JNK 2 items
  39. SGK 2 items
  40. Bcr-Abl 10 items
  41. MEK 5 items
  42. PORCN 1 item
  43. DOT1L 1 item
  44. FGFR 6 items
  45. Pim 4 items
  46. Glucagon-like peptide 1 (GLP-1) receptors 1 item
  47. Smoothened 2 items
  48. Eukaryotic elongation factors 1 item
  49. Ribosomal s6 kinases (RSK) 1 item
  50. MET 5 items
  51. Ras 1 item
  52. Src 8 items
  53. Trk Receptors 4 items
  54. STAT 3 items
  55. Microtubules/Tubulins 4 items
  56. EGFR 12 items
  57. Hedgehog 1 item
  58. Reverse Transcriptases 1 item
  59. ROCK 7 items
  60. BTK 1 item
  61. PAK 3 items
  62. FAK 4 items
  63. BMP and Other Activin Receptors 2 items
  64. JAK 9 items
  65. p300 1 item
  66. Syk 5 items
  67. DNA-PK 3 items
  68. HSP90 1 item
  69. AMPK 2 items
  70. PDHK 1 item
  71. CFTR 3 items
  72. TNKS 1 item
  73. ErbB 2 items
  74. S6 kinases 1 item
  75. Toll-like receptors (TLRs) 1 item
  76. Adenosine Kinases 2 items
  77. DNA Methyltransferases 1 item
  78. Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitors (HIF-PHIs) 1 item
  79. ERK 2 items
  80. c-MET 5 items
  81. BMI-1 1 item
  82. PKC 5 items
  83. Calpains 1 item
  84. Ubiquitin-specific proteases 1 item
  85. Ca2 /calmodulin-dependent protein kinases (CaMKs) 6 items
  86. Lyn 1 item
  87. SGLT 1 item
  88. HER2 2 items
  89. Pyk2 3 items
  90. USP 1 item
  91. LRRK2 4 items
  92. Insulin and Insulin-like Receptors 2 items
  93. ALK 3 items
  94. ROS1 1 item
  95. Sphingosine kinases (SphKs) 2 items
  96. GTPases 1 item
  97. PKG 1 item
  98. PKA 1 item
  99. Myosin light chain kinases (MLCKs) 2 items
  100. CaM-KK 1 item
  101. MELK 1 item
  102. Insulin-like growth factors (IGFs) 1 item
  103. Clk 1 item
  104. NUAK1 1 item
  105. NUAK2 1 item
  106. MK2 2 items
  107. Fatty-acid-binding proteins (FABPs) 1 item
  108. Tie-2 2 items
  109. RSK 1 item
  110. Granzyme B 1 item
  111. Free Fatty Acid Receptors 1 item
  112. phosphatases 1 item
  113. Autophagy 2 items
  114. ATM/ATR 4 items
  115. CK1 1 item
  116. Farnesyl Diphosphate Synthases 1 item
  117. CK2 3 items
  118. HIPK2 1 item
  119. HIPK3 1 item
  120. Melatonin Receptors 1 item
  121. Peroxynitrite 1 item
  122. P2X Receptors 1 item
  123. MAGL 1 item
  124. NPY Receptors 1 item
  125. c-Fyn 1 item
  126. TAK1 1 item
  127. Histamine H1 Receptors 2 items
  128. P110 1 item
  129. Hck 1 item
  130. TRP Channel 1 item
  131. Apoptosis Inducers 1 item
  132. NO Donors / Precursors 1 item
  133. IL Receptors 1 item
  134. 15-lipoxygenases 1 item
  135. Insulin Receptors 1 item
  136. IRG-1R 1 item
  137. Cdc2-like kinase (Clk) 1 item
  138. eEF-2 1 item
  139. Peptidoglycan synthesis 1 item
  140. Cdc7 2 items
  141. ZAP-70 1 item
  142. O6-methylguanine-DNA-methyl-transferase (MGMT) 1 item
  143. Aldosterone receptor 1 item
  144. DPP-4 1 item
  145. DREADD Ligands 1 item
  146. c-RET 1 item
  147. p70 rsk 1 item
  148. TAM kinase 1 item
  149. p53-MDM2 interaction 1 item
  150. AXL 1 item
  151. c-Fms tyrosine kinase 1 item
  152. Ub-conjugating enzyme (E2) complex 1 item
  153. STK 1 item
  154. MSK 1 item
  155. Lyn kinase 1 item
  156. ITK 1 item
  157. NUAK 1 item
  158. DCLK2 1 item
  159. Lck 1 item
  160. PKD 1 item
  161. Bcl-w 1 item
  162. tropomyosin receptor kinase 1 item
  163. SK 1 item
  164. FXR 1 item
  165. ATM 1 item
  166. Sirtuin 1 item
  167. PIKfyve 1 item
  168. Insulin Receptor 1 item
Reported Experiments
  1. Animal Experiments 316 items
  2. Cell Experiments 196 items
Related Disease
  1. Acute Myelogenous Leukemia 2 items
  2. Acute Myeloid Leukemia 18 items
  3. Adrenocortical Carcinoma 2 items
  4. Advanced Renal Cell Carcinoma 1 item
  5. Autoimmune Diseases 1 item
  6. Bladder Cancer 7 items
  7. Bladder Carcinoma 1 item
  8. B-lymphoid Malignancies 1 item
  9. Breast Cancer 66 items
  10. Cancer 225 items
  11. Cervical Cancer 4 items
  12. Cholangiocarcinoma 2 items
  13. Chronic Lymphocytic Leukemia 2 items
  14. Clear Cell Renal Cell Carcinoma 1 item
  15. Colon Cancer 30 items
  16. Colon Carcinoma 3 items
  17. Colorectal Cancer 29 items
  18. Diabetes 2 items
  19. Fungal Infection 1 item
  20. Glioblastoma 20 items
  21. Glioma 7 items
  22. Hepatocellular Carcinoma 6 items
  23. HIV 1 item
  24. HIV Infections 1 item
  25. Immunological Diseases 1 item
  26. Immunosuppressive Therapy 1 item
  27. Inflammatory Bowel Disease 1 item
  28. Inflammatory Diseases 8 items
  29. Leukemia 12 items
  30. Liver Cancer 4 items
  31. Lung Cancer 21 items
  32. Lung Carcinoma 3 items
  33. Lymphoma 12 items
  34. Mantle Cell Lymphoma 2 items
  35. Medulloblastoma 1 item
  36. Melanoma 19 items
  37. Mixed Lineage Leukemia 1 item
  38. Multiple Myeloma 11 items
  39. Myelofibrosis 1 item
  40. Myeloma 2 items
  41. Neuroblastoma 3 items
  42. Non-small Cell Lung Cancer 11 items
  43. Non-small Cell Lung Carcinoma 1 item
  44. Ovarian Cancer 22 items
  45. Pain Relief 1 item
  46. Pancreatic Cancer 27 items
  47. Pancreatic Carcinoma 2 items
  48. Prostate Cancer 29 items
  49. Psoriasis 2 items
  50. Pulmonary Arterial Hypertension 1 item
  51. Pulmonary Fibrosis 1 item
  52. Renal Cancer 3 items
  53. Renal Cell Carcinoma 8 items
  54. Rheumatoid Arthritis 6 items
  55. Sleep Disorders 1 item
  56. Thyroid Cancer 5 items
  57. Type 2 Diabetes 4 items