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  • Search results for: 'research-area cell-cycle aurora-kinase-a'

Search results for: 'research-area cell-cycle aurora-kinase-a'

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Items 21-30 of 1086

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  1. Rigosertib sodium salt
    A1404 Rigosertib sodium salt
     1 Citation
    Target: PLK
    Summary: Plk1 inhibitor
      ≥23.65 mg/mL
  2. Paclitaxel (Taxol)
    A4393 Paclitaxel (Taxol)
     4 Citation
    Target: Microtubules/Tubulins
    Summary: Antineoplastic agent
      ≥42.6955 mg/mL
      ≥31.6 mg/mL
      <4.46 mg/mL
  3. GSK429286A
    A5611 GSK429286A
    Target: ROCK
    Summary: Selective ROCK1/ROCK2 inhibitor
      ≥21.6 mg/mL
      ≥2.73 mg/mL
      <3.56 mg/mL
  4. BI 2536
    A3965 BI 2536
     1 Citation
    Target: PLK|Bromodomain-containing proteins(BRDs)
    Summary: Plk1 inhibitor,potent and ATP-competitive
      ≥13.04 mg/mL
      ≥92.4 mg/mL
      <2.56 mg/mL
  5. Y-27632 dihydrochloride
    A3008 Y-27632 dihydrochloride
     19 Citation
    Target: ROCK
    Summary: ROCK1 inhibitor
      ≥16.013 mg/mL
  6. Ro3280
    A8681 Ro3280
    Target: PLK
    Summary: PLK1 inhibitor,potent and highly selective
      ≥27.2 mg/mL
  7. CHIR-124
    A8394 CHIR-124
    Target: FLT3|GSK-3|Chk|PDGFR
    Summary: Chk1 inhibitor,novel and potent
      ≥10.5 mg/mL
  8. SLx-2119
    A3825 SLx-2119
     1 Citation
    Target: ROCK
    Summary: Selective ROCK2 inhibitor
      ≥22.65 mg/mL
      ≥26.4 mg/mL
      <2.46 mg/mL
  9. ZM 447439
    A4113 ZM 447439
    Target: Aurora Kinases|MEK|Src|Lck
    Summary: Aurora Kinase inhibitor,potent and selective
      ≥25.7 mg/mL
      <2.2 mg/mL
      <1.24 mg/mL
  10. JNJ-7706621
    A4115 JNJ-7706621
     1 Citation
    Target: Cyclin-Dependent Kinases|Aurora Kinases
    Summary: Potent CDK/Aurora kinase inhibitor
      ≥19.7 mg/mL
      <2.28 mg/mL
      <2.36 mg/mL

Items 21-30 of 1086

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  • Amino Acids & Building Blocks 2items
  • Kits 3items
  • Natural Products 24items
  • Protein 1item
  • Signaling Pathways 999items
  • Tag Peptides 4items
Reversibility
  1. Reversible 53 items
  2. Irreversible 30 items
Target
  1. Caspases 12 items
  2. Cyclin-Dependent Kinases 25 items
  3. Adenosine A2A Receptors 6 items
  4. Proteasome 10 items
  5. Cathepsins 12 items
  6. Histone Deacetylases (HDACs) 28 items
  7. Inhibitor of apoptosis proteins (IAP) 3 items
  8. Akt 6 items
  9. Bcl-2 6 items
  10. PI3K 25 items
  11. CXCR 7 items
  12. Raf 10 items
  13. Aurora Kinases 14 items
  14. Bcl-xl 3 items
  15. CSF-1R 2 items
  16. Glycoproteins 1 item
  17. Gap Junctions 3 items
  18. MDM2 2 items
  19. EZH2 6 items
  20. mTOR 15 items
  21. Bromodomains 5 items
  22. AP-1 3 items
  23. MMP 11 items
  24. Thymidine Phosphorylases 1 item
  25. Androgen Receptors 4 items
  26. Peptidylprolyl isomerases 1 item
  27. Acyl coenzyme A: cholesterol acyltransferases 1 item
  28. Myosin II ATPases 1 item
  29. DT-diaphorases 1 item
  30. Voltage-gated Potassium (KV) Channels 1 item
  31. MER 1 item
  32. FLT3 11 items
  33. GSK-3 9 items
  34. Factor Xa 3 items
  35. Farnesoid X receptors (FXRs) 1 item
  36. LPA Receptors 3 items
  37. P-glycoprotein (P-gp) 6 items
  38. PLK 6 items
  39. Chk 8 items
  40. ULK1 1 item
  41. Eph Receptors 3 items
  42. VEGFR 26 items
  43. PDGFR 18 items
  44. c-Kit 6 items
  45. RET 3 items
  46. IRAK 3 items
  47. Bromodomain-containing proteins(BRDs) 1 item
  48. Phosphodiesterases (PDEs) 11 items
  49. Mcl-1 3 items
  50. Hydrolase 1 item
  51. Thymidylate Synthase 2 items
  52. p38 8 items
  53. PKB 1 item
  54. 3-phosphoglycerate dehydrogenase 1 item
  55. JNK 5 items
  56. SGK 2 items
  57. Bcr-Abl 10 items
  58. Kynurenine-3-monooxygenase 1 item
  59. MEK 15 items
  60. PORCN 1 item
  61. DOT1L 3 items
  62. FGFR 9 items
  63. Nrf2 3 items
  64. Insulin-like growth factor receptors(IGFRs) 1 item
  65. CGRP receptors 2 items
  66. Pim 5 items
  67. GABAB Receptors 2 items
  68. Liver X receptors (LXRs) 2 items
  69. Glucagon-like peptide 1 (GLP-1) receptors 2 items
  70. Sir2-like Family Deacetylases (Sirtuins) 3 items
  71. Voltage-gated Sodium (NaV) Channels 6 items
  72. Deubiquitinating enzymes (DUBs) 5 items
  73. PP1 1 item
  74. PP2A 1 item
  75. Smoothened 5 items
  76. Eukaryotic elongation factors 1 item
  77. Ribosomal s6 kinases (RSK) 1 item
  78. Neuraminidases (NA) 2 items
  79. MET 7 items
  80. Glucan synthase 1 item
  81. Ras 1 item
  82. Src 8 items
  83. RARs 9 items
  84. Trk Receptors 7 items
  85. Integrins 1 item
  86. Aminopeptidases 2 items
  87. NMDA Receptors 2 items
  88. STAT 8 items
  89. Endothelin receptors 1 item
  90. ATP Citrate Lyases 1 item
  91. Microtubules/Tubulins 7 items
  92. Estrogen and Related Receptors 5 items
  93. EGFR 14 items
  94. Hedgehog 1 item
  95. Reverse Transcriptases 1 item
  96. ROCK 7 items
  97. BTK 2 items
  98. Purinergic (P2Y) Receptors 1 item
  99. RIP kinases 1 item
  100. Monocyte chemotactic proteins 1 item
  101. PAK 3 items
  102. Hypoxia Inducible Factors (HIFs) 1 item
  103. Tankyrases 1 item
  104. FAK 5 items
  105. BMP and Other Activin Receptors 4 items
  106. JAK 11 items
  107. p300 1 item
  108. Stearoyl-CoA 9-desaturase (SCD-1) 1 item
  109. Syk 6 items
  110. Progesterone Receptors 3 items
  111. EZH1 2 items
  112. DNA-PK 6 items
  113. HSP90 9 items
  114. AMPK 5 items
  115. Gutathione S-transferase 1 item
  116. CCR 2 items
  117. PDHK 1 item
  118. Angiotensin AT2 Receptors 3 items
  119. Notch 1 item
  120. S-nitrosoglutathione reductase 1 item
  121. CFTR 4 items
  122. TNKS 1 item
  123. Topoisomerases 7 items
  124. Cytochrome P450 (CYP450) 10 items
  125. M3 Receptors 2 items
  126. thrombin 1 item
  127. Ksp 1 item
  128. Ribosomes 1 item
  129. Renin 2 items
  130. HIV proteases 1 item
  131. Pepsins 1 item
  132. Influenza viruses 1 item
  133. ErbB 2 items
  134. Ferroptosis 1 item
  135. S6 kinases 1 item
  136. Toll-like receptors (TLRs) 4 items
  137. Adenosine Kinases 2 items
  138. Actin 3 items
  139. DNA Methyltransferases 3 items
  140. Epac 1 item
  141. Calcitonin and Related Receptors 1 item
  142. Survivin 1 item
  143. Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitors (HIF-PHIs) 1 item
  144. ERK 5 items
  145. HMG-CoA Reductases 5 items
  146. Vacuolar-type ATPase 1 item
  147. c-MET 9 items
  148. BMI-1 1 item
  149. PKC 7 items
  150. Calpains 6 items
  151. CysLT1 1 item
  152. Ubiquitin-specific proteases 1 item
  153. M1 Receptors 1 item
  154. HCV Proteases 3 items
  155. Ca2 /calmodulin-dependent protein kinases (CaMKs) 7 items
  156. MLK3 1 item
  157. SMYD2 1 item
  158. O-GlcNAcase 1 item
  159. CREBBP 2 items
  160. EP300 2 items
  161. Protease-Activated Receptors 1 item
  162. Lyn 1 item
  163. SGLT 2 items
  164. Trypsins 1 item
  165. HER2 2 items
  166. Pyk2 3 items
  167. USP 3 items
  168. 5-HT2 Receptors 12 items
  169. LRRK2 4 items
  170. Calcium ionophores 1 item
  171. S1P receptors 3 items
  172. Voltage-gated Calcium Channels (CaV) 6 items
  173. Calcium chelator 1 item
  174. DGAT 2 items
  175. Insulin and Insulin-like Receptors 4 items
  176. Mitochondrial apoptosis-induced channel (MAC) 1 item
  177. PARP 5 items
  178. CB1 Receptors 2 items
  179. Melanocortin (MC) Receptors 1 item
  180. ALK 5 items
  181. ROS1 2 items
  182. Sphingosine kinases (SphKs) 2 items
  183. Trypsin 1 item
  184. Chymotrypsin 1 item
  185. Kallikrein 1 item
  186. Trypsinogen 1 item
  187. KRAS G12C 1 item
  188. GTPases 1 item
  189. Monocarboxylate transporters (MCTs) 1 item
  190. CETP 2 items
  191. NK1 Receptors 1 item
  192. Dehydrogenase 1 item
  193. PKG 1 item
  194. PKA 1 item
  195. Myosin light chain kinases (MLCKs) 2 items
  196. GPR30 2 items
  197. HIV-1 gp120 1 item
  198. D1 and D5 Receptors 5 items
  199. D2 Receptors 9 items
  200. D3 Receptors 5 items
  201. 5-HT1 Receptors 7 items
  202. 5-HT7 Receptors 2 items
  203. CaM-KK 1 item
  204. Valosin-containing protein (VCP) 1 item
  205. AdipoR1 1 item
  206. AdipoR2 2 items
  207. MELK 1 item
  208. Serotonin reuptake 1 item
  209. Insulin-like growth factors (IGFs) 1 item
  210. AMPA 1 item
  211. Clk 1 item
  212. TBK1 1 item
  213. MARK1 1 item
  214. NUAK1 2 items
  215. Integrin-ligand interactions 1 item
  216. Bromodomain and Extra-Terminal motif (BET) 1 item
  217. NUAK2 1 item
  218. Adenylate cyclase 1 item
  219. Lactate Dehydrogenases (LDH) 1 item
  220. MK2 2 items
  221. Fatty-acid-binding proteins (FABPs) 1 item
  222. 5-HT3 Receptors 3 items
  223. 5-HT6 Receptors 1 item
  224. Angiotensin-Converting Enzymes (ACEs) 4 items
  225. Tie-2 4 items
  226. RSK 2 items
  227. p70 S6K 1 item
  228. Granzyme B 1 item
  229. Free Fatty Acid Receptors 3 items
  230. phosphatases 2 items
  231. ROS and Other Gaseous Donors 1 item
  232. Autophagy 3 items
  233. ATM/ATR 7 items
  234. Acetylcholine 1 item
  235. COX 7 items
  236. C5a receptors 1 item
  237. Folate Analogue 1 item
  238. YAP 1 item
  239. CK1 1 item
  240. IDH2 1 item
  241. Histamine H4 Receptors 2 items
  242. Farnesyl Diphosphate Synthases 1 item
  243. CK2 3 items
  244. HIPK2 1 item
  245. HIPK3 1 item
  246. HIV Integrases 2 items
  247. Pregnane X Receptors 1 item
  248. G-quadruplexes 1 item
  249. Squalene epoxidases 2 items
  250. Delayed rectifier outward potassium current (IKr) 1 item
  251. GpIIb/IIIa receptor 1 item
  252. Melatonin Receptors 2 items
  253. 20S proteasomal chymotrypsin 1 item
  254. Geranylgeranyltransferase I 1 item
  255. Farnesyltransferase 1 item
  256. Peroxynitrite 1 item
  257. Nampt 2 items
  258. eIF4F 1 item
  259. Cdc42 1 item
  260. P2X Receptors 2 items
  261. Carbonic Anhydrases 7 items
  262. Ron 1 item
  263. AP endonucleases 1 item
  264. G9a 2 items
  265. BLM 1 item
  266. HSV 1 item
  267. Adenosine A2B Receptors 1 item
  268. NADPH Oxidases 2 items
  269. Glutamate (Metabotropic) Group I Receptors 3 items
  270. Calcium-activated chloride channels (CaCC) 1 item
  271. GPR35 1 item
  272. Aldehyde Dehydrogenases 2 items
  273. Synthases/Synthetases 5 items
  274. MAGL 2 items
  275. NPY Receptors 1 item
  276. c-Fyn 1 item
  277. Leukotriene and Related Receptors 1 item
  278. TAK1 1 item
  279. Histamine H1 Receptors 11 items
  280. RAR/RXR 1 item
  281. Sigma Receptors 1 item
  282. Na /K ATPases 2 items
  283. Nur77 1 item
  284. P110 1 item
  285. Hck 1 item
  286. Inositol-requiring enzyme 1 (IRE1) 1 item
  287. SETD7 1 item
  288. Na /K /Cl- Symporters (NKCCs) 1 item
  289. GABAA Receptors 2 items
  290. iNOS 1 item
  291. Opioid receptors 1 item
  292. Histamine H2 Receptors 1 item
  293. Phospholipases 2 items
  294. Monoamine oxidases (MAOs) 1 item
  295. Organic anion transporters (OATs) 1 item
  296. TRP Channel 4 items
  297. RNA Polymerases 3 items
  298. DYRK 1 item
  299. Norepinephrine transporter 1 item
  300. 5-HT Transporters 3 items
  301. Ionophores 1 item
  302. Xanthine oxidoreductases 1 item
  303. Dihydroorotate dehydrogenase 1 item
  304. Guanylyl Cyclases 1 item
  305. FoxM1 1 item
  306. Histone Demethylases 2 items
  307. Apoptosis Inducers 1 item
  308. MNK 1 item
  309. 5-Lipoxygenases 1 item
  310. NO Donors / Precursors 2 items
  311. CB2 Receptors 3 items
  312. Glucocorticoid Receptors 5 items
  313. Adenosine A1 Receptors 1 item
  314. IL Receptors 2 items
  315. CCL2 1 item
  316. Para-aminobenzoic acid 1 item
  317. Noradrenaline reuptake 1 item
  318. Norepinephrine transporters 1 item
  319. 15-lipoxygenases 1 item
  320. Calcium-Activated Potassium (KCa) Channels 3 items
  321. 5-HT4 Receptors 1 item
  322. AChE 2 items
  323. Insulin Receptors 1 item
  324. IRG-1R 1 item
  325. Proton Pump 1 item
  326. Cdc2-like kinase (Clk) 1 item
  327. eEF-2 1 item
  328. Inward Rectifier Potassium (Kir) Channels 5 items
  329. Arp2/3 complex 1 item
  330. Peptidoglycan synthesis 2 items
  331. Tetrahydrofolate dehydrogenase 1 item
  332. CRTH2 1 item
  333. Cdc7 2 items
  334. Nuclear Receptors 1 item
  335. CMV 2 items
  336. ZAP-70 1 item
  337. Catechol O-Methyltransferase (COMT) 2 items
  338. fibrinolysis 1 item
  339. Angiotensin AT1 Receptors 3 items
  340. D4 Receptors 2 items
  341. O6-methylguanine-DNA-methyl-transferase (MGMT) 1 item
  342. Aldosterone receptor 1 item
  343. HBV Proteases 1 item
  344. Hydroxylases 1 item
  345. Flk-1 1 item
  346. Adenine receptors 1 item
  347. Antioxidants 1 item
  348. Papains 1 item
  349. RNA synthesis 1 item
  350. Na /Ca2 Exchangers (NCXs) 1 item
  351. NAE 2 items
  352. Ubiquitin-activating Enzyme E1 1 item
  353. SUMOylation 1 item
  354. ATGL 1 item
  355. BACE 1 item
  356. Cytidine deaminases 1 item
  357. GPR40 1 item
  358. Adenylyl Cyclases 1 item
  359. angiogenesis 1 item
  360. Glucagon Receptors 1 item
  361. 15-PGDH 1 item
  362. DPP-4 4 items
  363. DREADD Ligands 1 item
  364. PP4 1 item
  365. c-RET 1 item
  366. Nonstructural protein 5B (NS5B) 1 item
  367. ETA Receptors 2 items
  368. ETB Receptors 1 item
  369. p70 rsk 1 item
  370. FPTase 1 item
  371. Retinoic acid-related Orphan Receptors (RORs) 1 item
  372. ADAMs 1 item
  373. TAM kinase 1 item
  374. p53-MDM2 interaction 1 item
  375. nuclear export 1 item
  376. CRM1 1 item
  377. endothelin receptor 1 item
  378. PARs 1 item
  379. AXL 1 item
  380. Protein polybromo-1 1 item
  381. SMARCA4 1 item
  382. SMARCA2 1 item
  383. adrenoceptor 2 items
  384. HDAC 1 item
  385. 5-HT6 Receptor 1 item
  386. c-Fms tyrosine kinase 1 item
  387. PAR 1 item
  388. human lyase 1 item
  389. Ub-conjugating enzyme (E2) complex 1 item
  390. PPAR 2 items
  391. STK 1 item
  392. IKK 1 item
  393. MSK 1 item
  394. HCV polymerase 2 items
  395. Lyn kinase 1 item
  396. Ftase 1 item
  397. PC-PLC 1 item
  398. Elastases 1 item
  399. P97 ATPase 1 item
  400. cannabinoid receptor 1 item
  401. Calcium-Sensing Receptors (CaSRs) 1 item
  402. Rev-Erb Receptors 1 item
  403. telomerase 1 item
  404. Prostanoid Receptors 1 item
  405. Histone Acetyltransferases (HATs) 1 item
  406. Retinoid X receptors (RXR) 1 item
  407. F1 Fo-ATPase 1 item
  408. Glutamate (EAAT) Transporters 1 item
  409. ITK 1 item
  410. NOD1 1 item
  411. NUAK 1 item
  412. DCLK2 1 item
  413. FAAH 1 item
  414. Lck 1 item
  415. NOP Receptors 1 item
  416. Aromatases 1 item
  417. PKD 1 item
  418. MCL1 1 item
  419. Bcl-w 1 item
  420. LSD 1 item
  421. GLP 1 item
  422. SK 1 item
  423. MST 1 item
  424. IDO 1 item
  425. FXR 1 item
  426. Serotonin (5-HT) reuptake 1 item
  427. Androgen Receptor 1 item
  428. Substance P/NK1 Receptor 1 item
  429. gp120/CD4 1 item
  430. ATM 2 items
  431. Sirtuin 1 item
  432. NE 1 item
  433. CRF1 Receptors 1 item
  434. PIKfyve 1 item
  435. Glycogen Phosphorylases 1 item
  436. RGS 1 item
  437. MTH1 1 item
  438. Insulin Receptor 1 item
Reported Experiments
  1. Animal Experiments 934 items
  2. Cell Experiments 651 items
Related Disease
  1. Abscesses And Esophageal Candidiasis 1 item
  2. Acne 1 item
  3. Acute Disseminated Candidiasis 1 item
  4. Acute Kidney Injury 2 items
  5. Acute Lung Injury 1 item
  6. Acute Myelogenous Leukemia 6 items
  7. Acute Myeloid Leukemia 28 items
  8. Acute Renal Failure 1 item
  9. Adrenocortical Carcinoma 3 items
  10. Advanced Renal Cell Carcinoma 1 item
  11. Autoimmune Diseases 1 item
  12. Bacteria Infection 1 item
  13. Bacterial Infectios 1 item
  14. Biliary Cancer 1 item
  15. Bladder Cancer 12 items
  16. Bladder Carcinoma 3 items
  17. Bladder Diseases 2 items
  18. B-lymphoid Malignancies 1 item
  19. Brain Injuries Studies 3 items
  20. Breast Cancer 134 items
  21. Cancer 506 items
  22. Candida Peritonitis 1 item
  23. Candidemia 1 item
  24. Castration-resistant Prostate Cancer 1 item
  25. Cervical Cancer 6 items
  26. Cholangiocarcinoma 2 items
  27. Chronic Lymphocytic Leukemia 7 items
  28. Chronic Myeloproliferative Disorders 1 item
  29. Clear Cell Renal Cell Carcinoma 2 items
  30. Cocaine Abuse 1 item
  31. Cocaine-Related Disorders 3 items
  32. Colon Cancer 50 items
  33. Colon Carcinoma 6 items
  34. Colorectal Cancer 46 items
  35. Depression 4 items
  36. Diabetes 9 items
  37. Diffuse Large B-cell Lymphoma 1 item
  38. Dyskinesia 1 item
  39. Dyslipidemia 2 items
  40. Epilepsy 4 items
  41. Erectile Dysfunction 3 items
  42. Friedreich's Ataxia 2 items
  43. Fungal Infection 3 items
  44. Glioblastoma 35 items
  45. Glioma 16 items
  46. HCV 3 items
  47. Heart Failure 1 item
  48. Hepatic Cancer 2 items
  49. Hepatitis C 3 items
  50. Hepatocellular Carcinoma 10 items
  51. HIV 6 items
  52. HIV Infections 12 items
  53. Hypercholesterolemia 2 items
  54. Immunological Diseases 1 item
  55. Immunosuppressive Therapy 1 item
  56. Inflammation 1 item
  57. Inflammatory Bowel Disease 1 item
  58. Inflammatory Diseases 30 items
  59. Influenza 2 items
  60. Kidney Injury Studies 3 items
  61. Leukemia 33 items
  62. Liver Cancer 6 items
  63. Lung Cancer 52 items
  64. Lung Carcinoma 4 items
  65. Lymphoma 39 items
  66. Mantle Cell Lymphoma 2 items
  67. Medulloblastoma 1 item
  68. Melanoma 42 items
  69. Mixed Lineage Leukemia 3 items
  70. Multidrug Resistance Studies 1 item
  71. Multiple Myeloma 25 items
  72. Myelofibrosis 2 items
  73. Myeloma 7 items
  74. Narcolepsy 1 item
  75. Neuroblastoma 15 items
  76. Neurocognitive Disorders 1 item
  77. Neuronal Protection 1 item
  78. Non-small Cell Lung Cancer 26 items
  79. Non-small Cell Lung Carcinoma 3 items
  80. Obsessive-Compulsive Disorder 1 item
  81. Osteoporosis 3 items
  82. Ovarian Cancer 43 items
  83. Pain Relief 1 item
  84. Pancreatic Cancer 51 items
  85. Pancreatic Carcinoma 3 items
  86. Prostate Cancer 64 items
  87. Psoriasis 6 items
  88. Psoriasis Vulgaris 1 item
  89. Pulmonary Arterial Hypertension 2 items
  90. Pulmonary Fibrosis 2 items
  91. Renal Cancer 5 items
  92. Renal Cell Carcinoma 13 items
  93. Rheumatoid Arthritis 15 items
  94. Sarcoma 1 item
  95. Schizophrenia 13 items
  96. Sleep Disorders 2 items
  97. Soft Tissue Sarcoma 1 item
  98. Squamous Cell Carcinoma 3 items
  99. Testicular Cancer 2 items
  100. Thyroid Cancer 6 items
  101. Tuberculosis 2 items
  102. Type 2 Diabetes 28 items