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Search results for: 'research area cell cycle rad51'

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  1. R547
    A8642 R547
     2 Citation
    Target: Cyclin-Dependent Kinases
    Summary: CDK1/2/4 inhibitor,ATP-competitive
      soluble in dmso
  2. BS-181 HCl
    A5700 BS-181 HCl
    Target: Cyclin-Dependent Kinases
    Summary: CDK7 inhibitor,highly selective
      ≥20.85 mg/mL
      ≥6.49 mg/mL
      insoluble in h2o
  3. AZD-5438
    A8326 AZD-5438
     2 Citation
    Target: Cyclin-Dependent Kinases
    Summary: Potent CDK1/2/9 inhibitor
      ≥18.55 mg/mL
  4. AT7519 Hydrochloride
    A3197 AT7519 Hydrochloride
    Target: Cyclin-Dependent Kinases
    Summary: Multi-CDK inhibitor
      ≥43.3 mg/mL
      ≥8.82 mg/mL
      ≥29.93 mg/mL
  5. LEE011
    A8641 LEE011
    Target: Cyclin-Dependent Kinases
    Summary: CDK4/6 inhibitor
      ≥10.88 mg/mL
  6. Dinaciclib (SCH727965)
    A8412 Dinaciclib (SCH727965)
     2 Citation
    Target: Cyclin-Dependent Kinases
    Summary: Potent CDK inhibitor
      ≥17.15 mg/mL
  7. BMS265246
    A8385 BMS265246
    Target: Cyclin-Dependent Kinases
    Summary: CDK1/2 inhibitor,potent and selective
      ≥17.25 mg/mL
  8. PHA-848125
    A8501 PHA-848125
    Target: Cyclin-Dependent Kinases
    Summary: CDK inhibitor,potent and ATP-competitive
      ≥23.05 mg/mL
  9. Palbociclib (PD0332991) Isethionate
    A8335 Palbociclib (PD0332991) Isethionate
     1 Citation
    Target: Cyclin-Dependent Kinases
    Summary: CDK4/6 inhibitor,highly selective
      ≥28.7 mg/mL
  10. PD 0332991 (Palbociclib) HCl
    A8316 PD 0332991 (Palbociclib) HCl
     5 Citation
    Target: Cyclin-Dependent Kinases
    Summary: CDK4/6 inhibitor,highly selective
      ≥2.4 mg/mL
      ≥2.79 mg/mL
      ≥24.2 mg/mL

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Category
Specificity
  1. Selective 14 items
Target
  1. Caspases 8 items
  2. Cyclin-Dependent Kinases 17 items
  3. Proteasome 7 items
  4. Cathepsins 1 item
  5. Histone Deacetylases (HDACs) 16 items
  6. Inhibitor of apoptosis proteins (IAP) 1 item
  7. Akt 1 item
  8. Bcl-2 2 items
  9. PI3K 5 items
  10. Raf 2 items
  11. Aurora Kinases 6 items
  12. Bcl-xl 1 item
  13. Glycoproteins 1 item
  14. MDM2 1 item
  15. EZH2 3 items
  16. mTOR 2 items
  17. Bromodomains 1 item
  18. AP-1 2 items
  19. MMP 1 item
  20. Myosin II ATPases 1 item
  21. FLT3 2 items
  22. GSK-3 4 items
  23. LPA Receptors 1 item
  24. P-glycoprotein (P-gp) 3 items
  25. PLK 7 items
  26. Chk 4 items
  27. VEGFR 4 items
  28. PDGFR 3 items
  29. c-Kit 1 item
  30. Bromodomain-containing proteins(BRDs) 1 item
  31. Phosphodiesterases (PDEs) 2 items
  32. Hydrolase 1 item
  33. p38 1 item
  34. Bcr-Abl 1 item
  35. MEK 2 items
  36. PORCN 1 item
  37. DOT1L 1 item
  38. FGFR 2 items
  39. Glucagon-like peptide 1 (GLP-1) receptors 1 item
  40. Sir2-like Family Deacetylases (Sirtuins) 1 item
  41. Deubiquitinating enzymes (DUBs) 1 item
  42. Smoothened 2 items
  43. Eukaryotic elongation factors 1 item
  44. Ras 1 item
  45. Src 2 items
  46. Trk Receptors 2 items
  47. STAT 5 items
  48. Microtubules/Tubulins 4 items
  49. Estrogen and Related Receptors 1 item
  50. EGFR 8 items
  51. Hedgehog 1 item
  52. Reverse Transcriptases 1 item
  53. ROCK 7 items
  54. FAK 4 items
  55. JAK 5 items
  56. p300 1 item
  57. Stearoyl-CoA 9-desaturase (SCD-1) 1 item
  58. Syk 1 item
  59. DNA-PK 2 items
  60. HSP90 1 item
  61. AMPK 2 items
  62. CFTR 3 items
  63. TNKS 1 item
  64. Cytochrome P450 (CYP450) 1 item
  65. ErbB 2 items
  66. Toll-like receptors (TLRs) 2 items
  67. DNA Methyltransferases 1 item
  68. Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitors (HIF-PHIs) 1 item
  69. ERK 1 item
  70. BMI-1 1 item
  71. PKC 5 items
  72. Calpains 1 item
  73. Ca2 /calmodulin-dependent protein kinases (CaMKs) 2 items
  74. Lyn 1 item
  75. SGLT 1 item
  76. RAD51 2 items
  77. Pyk2 3 items
  78. USP 1 item
  79. LRRK2 2 items
  80. Voltage-gated Calcium Channels (CaV) 1 item
  81. Insulin and Insulin-like Receptors 1 item
  82. ALK 3 items
  83. Sphingosine kinases (SphKs) 1 item
  84. GTPases 1 item
  85. PKA 3 items
  86. Fatty-acid-binding proteins (FABPs) 1 item
  87. Tie-2 1 item
  88. Granzyme B 1 item
  89. Free Fatty Acid Receptors 1 item
  90. phosphatases 1 item
  91. Autophagy 2 items
  92. ATM/ATR 5 items
  93. CK1 1 item
  94. Farnesyl Diphosphate Synthases 1 item
  95. HIV Integrases 1 item
  96. Melatonin Receptors 1 item
  97. Peroxynitrite 1 item
  98. MAGL 1 item
  99. NPY Receptors 1 item
  100. c-Fyn 1 item
  101. Histamine H1 Receptors 3 items
  102. RAR/RXR 1 item
  103. TRP Channel 1 item
  104. DYRK 1 item
  105. Apoptosis Inducers 1 item
  106. MNK 1 item
  107. NO Donors / Precursors 1 item
  108. Glucocorticoid Receptors 1 item
  109. IL Receptors 1 item
  110. 15-lipoxygenases 1 item
  111. Inward Rectifier Potassium (Kir) Channels 2 items
  112. Peptidoglycan synthesis 1 item
  113. O6-methylguanine-DNA-methyl-transferase (MGMT) 1 item
  114. NMDA receptor 1 item
  115. Aldosterone receptor 1 item
  116. RNA synthesis 1 item
  117. DPP-4 1 item
  118. DREADD Ligands 1 item
  119. p70 rsk 1 item
  120. Microtubule/Tubulin 2 items
  121. p53-MDM2 interaction 1 item
  122. KDR 1 item
  123. p53 3 items
  124. c-Fms tyrosine kinase 1 item
  125. insulin 1 item
  126. Ub-conjugating enzyme (E2) complex 1 item
  127. Smoothened receptor 1 item
  128. PPAR 1 item
  129. HDM2 ubiquitin ligase 1 item
  130. Glucosidases 1 item
  131. Vitamin D receptors (VDRs) 1 item
  132. Antibiotic 1 item
  133. DNA Alkylating 1 item
  134. GLI 1 item
  135. Stem Cell Differentiation 1 item
  136. PP2A/Nkd interaction 1 item
  137. adrenergic receptor 1 item
  138. Ribonucleotide Reductases 1 item
  139. Aryl hydrocarbon receptors (AHRs) 1 item
  140. DCLK2 1 item
  141. phosphatidylinositol kinase 1 item
  142. Lck 1 item
  143. Adenosine Deaminases 1 item
  144. Histamine receptors 1 item
  145. GluR 1 item
  146. 5-HT receptor 1 item
  147. dopamine receptors 1 item
  148. AMPA receptor 1 item
  149. Flk1 1 item
  150. p21 1 item
  151. RHA 1 item
  152. TRPC channel 1 item
  153. FKBP 1 item
  154. Bcl-w 1 item
  155. PPK 1 item
  156. c-Syk 1 item
  157. CDK1/CyclinB 1 item
  158. glucose uptake 1 item
  159. FXR 1 item
  160. Vascular Disrupting Agents (VDA) 1 item
  161. ATM 1 item
  162. Sirtuin 1 item
  163. PIKfyve 1 item
  164. Bax 1 item
  165. NS3/4a Proteases 1 item
  166. p90 S6K 1 item
Reported Experiments
  1. Animal Experiments 14 items
  2. Cell Experiments 9 items
Related Disease
  1. Acute Myeloid Leukemia 3 items
  2. B-lymphoid Malignancies 1 item
  3. Breast Cancer 5 items
  4. Cancer 15 items
  5. Chronic Lymphocytic Leukemia 1 item
  6. Colon Cancer 2 items
  7. Glioblastoma 2 items
  8. Lymphoma 1 item
  9. Mantle Cell Lymphoma 1 item
  10. Melanoma 1 item
  11. Multiple Myeloma 1 item
  12. Neuroblastoma 1 item
  13. Ovarian Cancer 3 items
  14. Pancreatic Cancer 2 items