Search results for: 'hsp'
- HSP990 (NVP-HSP990)Catalog No. :B4797Hsp90 inhibitor, potent and selectiveHSP990 (NVP-HSP990) is a potent and selective inhibitor of HSP90 with IC50 values of 0.6, 0.8 and 8.5 nM for Hsp90α, Hsp90β and Grp94, respectively .
- Heat Shock Protein 90 (Hsp90), human recombinant proteinCatalog No. :P1070Heat Shock Protein 90, expressed in Sf9 cells, suitable for cell culture.
Hsp90 (heat shock protein 90) is a molecular chaperone with a mass molecular of roughly 83.1 kDa.
- Ganetespib (STA-9090)Catalog No. :A4385Hsp90 inhibitor,non-geldanamycin
Ganetespib (also known as STA-9090), 5-[2,4-dihydroxy-5-(1 methylethyl)phenyl]-2,4 dihydro-4-(1-methyl-1H indol-5 yl)-3H-1,2,4 triazole-3-one, is a potent small-molecule inhibitor of heat shock protein 90 (Hsp90), which binds to the ATP pocket in the N-terminus of Hsp90 resulting in down-regulation of Hsp90 client protein levels.
- RetaspimycinCatalog No. :A3756HSP90 inhibitor,antiproliferative and antineoplasticRetaspimycin is a water-soluble hydroquinone hydrochloride salt inhibitor of Hsp90 .
- XL-888Catalog No. :A4388Hsp90 inhibitor
XL-888 is a novel and orally-bioavailable inhibitor of heat shock protein 90 (HSP90) that selectively inhibits HSP90α and HSP90β with values of 50% inhibition concentration IC50 of 22 nM and 44 nM respectively.
- VER 155008Catalog No. :A4387HSP 70 inhibitor,adenosine-derived
VER 155008 is a potent inhibitor of heat shock protein 70 (Hsp70) family of chaperones, which have been shown to contribute to cancer cell survival via anti-apoptotic functions, that inhibits Hsp70 (with the value of 50% inhibition concentration IC50 of 0.5 μM) as well as heat shock cognate 71 kDa protein (Hsc70) and 78 kDa glucose-regulated protein (Grp78) but to a lesser extent.
- SNX-2112Catalog No. :A4068Hsp90 inhibitor,ATP-competitve,potent and selectiveSNX-2112 is a potent inhibitor of synthetic heat shock protein (Hsp 90) with IC50 value of 30 nM.
- PF-04929113 (SNX-5422)Catalog No. :A4065Hsp90 inhibitor,potent and selectivePF-04929113 is an inhibitor of Hsp90 .
- NVP-BEP800Catalog No. :A4064Oral Hsp90β inhibitor, novel, fully syntheticNVP-BEP800 is a fully synthetic, orally bioavailable inhibitor of Hsp90 with IC50 value of 58nM .
- KW-2478Catalog No. :A4062Potent Hsp90 inhibitor, novel, non-ansamycin,KW-2478 is a novel and potent nonansamycin inhibitor of heat shock protein 90 (Hsp90) to overcome the limitations, including low water solubility and hepatotoxicity, of 17-allylamino-17-demethoxygeldanamycin (17-AAG).